Zobrazeno 1 - 10
of 350
pro vyhledávání: '"D, Cooney"'
Autor:
Man K.S. Lee, Olivia D. Cooney, Xuzhu Lin, Shaktypreya Nadarajah, Dragana Dragoljevic, Kevin Huynh, Danise-Ann Onda, Sandra Galic, Peter J. Meikle, Thomas Edlund, Morgan D. Fullerton, Bruce E. Kemp, Andrew J. Murphy, Kim Loh
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101514- (2022)
Objectives: Dysregulation of cholesterol metabolism in the liver and hematopoietic stem and progenitor cells (HSPCs) promotes atherosclerosis development. Previously, it has been shown that HMG-CoA-Reductase (HMGCR), the rate-limiting enzyme in the m
Externí odkaz:
https://doaj.org/article/8e3ca735c9ca4ee3934879d9b15a6a5b
Autor:
Laura A. Regan, Nathan W. Bower, Samuel J. Brown, Craig C. Lundstrom, Gideon Bartov, Matthew D. Cooney
Publikováno v:
Forensic Sciences Research, Vol 6, Iss 1, Pp 42-52 (2021)
Isotopic signatures used in the georeferencing of human remains are largely fixed by spatially distinct geologic and environmental processes. However, location-dependent temporal changes in these isotope ratios should also be considered when determin
Externí odkaz:
https://doaj.org/article/b043cf25c84b4bfc9d7d0e32d297a8ce
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Over the past decade, the use of probiotics to modify the gut microbiome has become a public spotlight in reducing the severity of a number of chronic diseases such as autoimmune disease, diabetes, cancer and cardiovascular disease. Recently, the gut
Externí odkaz:
https://doaj.org/article/c0eadd7d04d846a583942fc14d364690
Autor:
Man K. S. Lee, Annas Al-Sharea, Waled A. Shihata, Camilla Bertuzzo Veiga, Olivia D. Cooney, Andrew J. Fleetwood, Michelle C. Flynn, Ellen Claeson, Clovis S. Palmer, Graeme I. Lancaster, Darren C. Henstridge, John A. Hamilton, Andrew J. Murphy
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation. During acute inflammation CD14+CD16− monocytes are sig
Externí odkaz:
https://doaj.org/article/877fdbb79e87480fa17aaf1845695887
Autor:
Annas Al-Sharea, Man K. S. Lee, Alexandra Whillas, Danielle L. Michell, Waled A. Shihata, Alyce J. Nicholls, Olivia D. Cooney, Michael J. Kraakman, Camilla Bertuzzo Veiga, Ann-Maree Jefferis, Kristy Jackson, Prabhakara R. Nagareddy, Gavin Lambert, Connie H. Y. Wong, Karen L. Andrews, Geoff A. Head, Jaye Chin-Dusting, Andrew J. Murphy
Publikováno v:
Haematologica, Vol 104, Iss 3 (2019)
Hypertension is a major, independent risk factor for atherosclerotic cardiovascular disease. However, this pathology can arise through multiple pathways, which could influence vascular disease through distinct mechanisms. An overactive sympathetic ne
Externí odkaz:
https://doaj.org/article/4e2a37be40d14ab48b844e3e3f467be4
Autor:
Lisa G Crozier, Michelle M McClure, Tim Beechie, Steven J Bograd, David A Boughton, Mark Carr, Thomas D Cooney, Jason B Dunham, Correigh M Greene, Melissa A Haltuch, Elliott L Hazen, Damon M Holzer, David D Huff, Rachel C Johnson, Chris E Jordan, Isaac C Kaplan, Steven T Lindley, Nathan J Mantua, Peter B Moyle, James M Myers, Mark W Nelson, Brian C Spence, Laurie A Weitkamp, Thomas H Williams, Ellen Willis-Norton
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0217711 (2019)
Major ecological realignments are already occurring in response to climate change. To be successful, conservation strategies now need to account for geographical patterns in traits sensitive to climate change, as well as climate threats to species-le
Externí odkaz:
https://doaj.org/article/ca5256e1e1564f4fb5a2d0ae7a8c7f89
Autor:
Ricardo C.T. Aguiar, Heinz Sill, Albert Wölfler, ZhiJun Qiu, Jamie Myers, Avvaru N. Suhasini, Long Wang, Daifeng Jiang, An-Ping Lin, Jeffrey D. Cooney
Cell viability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd43f45cc8d3130c73aa45e5d72c570
https://doi.org/10.1158/1078-0432.22464317.v1
https://doi.org/10.1158/1078-0432.22464317.v1
Autor:
Ricardo C.T. Aguiar, Heinz Sill, Albert Wölfler, ZhiJun Qiu, Jamie Myers, Avvaru N. Suhasini, Long Wang, Daifeng Jiang, An-Ping Lin, Jeffrey D. Cooney
Purpose: Aberrant activation of the B-cell receptor (BCR) is implicated in the pathogenesis of mature B-cell tumors, a concept validated in part by the clinical success of inhibitors of the BCR-related kinases BTK (Bruton's tyrosine kinase) and PI3K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4a51cd21d0de0aac7c04b696156adf
https://doi.org/10.1158/1078-0432.c.6525671.v1
https://doi.org/10.1158/1078-0432.c.6525671.v1
Autor:
Ricardo C.T. Aguiar, Heinz Sill, Albert Wölfler, ZhiJun Qiu, Jamie Myers, Avvaru N. Suhasini, Long Wang, Daifeng Jiang, An-Ping Lin, Jeffrey D. Cooney
CLL features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc3580807f540146307278329fd2098
https://doi.org/10.1158/1078-0432.22464299
https://doi.org/10.1158/1078-0432.22464299