Zobrazeno 1 - 10
of 322
pro vyhledávání: '"D, Conte Camerino"'
Autor:
J. F. Desaphy, Emanuela Longa, Rizwan Qaisar, Monica Canepari, Valentina Agoni, Roberto Bottinelli, D. Conte Camerino, Manuela Maffei
Publikováno v:
Acta Physiologica. 212:316-329
Aim Notwithstanding the widely accepted idea that following disuse skeletal muscles become faster, an increase in shortening velocity was previously observed mostly in fibres containing type 1 myosin, whereas a decrease was generally found in fibres
Autor:
J. F. Desaphy, D. Conte Camerino, Teresa Costanza, Alfred L. George, Carlo Franchini, Claudio Bruno, Giovanni Lentini, Antonella Dipalma
Publikováno v:
British Journal of Pharmacology. 160:1521-1533
Background and purpose: Pilsicainide, an anti-arrhythmic drug used in Japan, is described as a pure sodium channel blocker. We examined the mechanisms by which it is able to block open channels, because these properties may be especially useful to re
Autor:
Antonella Liantonio, Alessandra Picollo, Michael Pusch, D. Conte Camerino, Viviana Giannuzzi, Elena Babini
Publikováno v:
British Journal of Pharmacology. 150:235-247
Background and purpose: Given the crucial role of the skeletal muscle chloride conductance (gCl), supported by the voltage- gated chloride channel CLC-1, in controlling muscle excitability, the availability of ligands modulating CLC-1 are of potentia
Autor:
Maria Maddalena Cavalluzzi, Vincenzo Tortorella, A. De Luca, D. Conte Camerino, Francesco Rana, Giovanni Lentini, Carlo Franchini, Alessia Catalano, M. De Bellis
Publikováno v:
British Journal of Pharmacology. 149:300-310
Background and purpose: Mexiletine (Mex), an orally effective antiarrhythmic agent used to treat ventricular arrhythmias, has also been found to be effective for myotonia and neuropathic pain. It is extensively metabolized in humans but little inform
Autor:
Michela De Bellis, Carlo Franchini, Jean-François Desaphy, Filomena Corbo, S. Talon, Alessia Catalano, Vincenzo Tortorella, D. Conte-Camerino, Annamaria De Luca, Giovanni Lentini
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 367:318-327
In striated fibers, the activity of mexiletine (Mex)-like sodium channel blockers is strongly modulated by the part of the molecule nearby the asymmetric carbon atom. A lipophilic aromatic phenyl group at this levels, as in 2-(2,6-dimethylphenoxy)-1-
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 434:822-829
In the present work, we have investigated the effects of the aging process on Ca2+-activated K+ channels (KCa2+) of rat skeletal muscle fibres. KCa2+ channels of adult (5-7 months old) and aged (24-26 months old) rats were surveyed by the patch-clamp
Autor:
Valeria A. Sansone, Adele D'Amico, Tiziana Mongini, Simona Portaro, M. Lo Monaco, G. Meola, Lorenzo Maggi, J. F. Desaphy, Serena Pagliarani, Luisa Politano, Maria Trojano, Paola Imbrici, Gabriele Siciliano, D. Conte Camerino, G. Comi, Pia Bernasconi, Sabrina Lucchiari, Elena Pegoraro, Antonio Toscano, Renato Mantegazza
Publikováno v:
Neuromuscular Disorders. 26:S197
Autor:
Francesco Campagna, Giovanni Casini, A. De Luca, D. Conte-Camerino, Sabata Pierno, Angelo Carotti, Fausta Palluotto, Domenico Tricarico
Publikováno v:
ChemInform. 26
A series of amidinosulfonic acids IIIa-f, analogs of taurine and homotaurine, was synthesized by reacting 2-aminoethane or 3-aminopropane sulfonic acid with lactim ethers Ia-c and then cyclized to sultams IVa-c and Vd-f. The effects of some selected
Autor:
D. Conte-Camerino, Rosa Amoroso, Savina Ferorelli, Giancarlo Bettoni, A. De Luca, Fulvio Loiodice, V. Tortorella
Publikováno v:
ChemInform. 29
Autor:
Carlo Franchini, Jean-François Desaphy, Marilena Muraglia, Carla Ghelardini, M. Norcini, Antonella Dipalma, Filomena Corbo, D. Conte Camerino, Marta Nesi, Marco Pistolozzi, Rosanna Matucci, Carlo Bertucci
Publikováno v:
Neuroscience. 169(2)
The role of voltage-gated sodium channels in the transmission of neuropathic pain is well recognized. For instance, genetic evidence recently indicate that the human Nav1.7 sodium channel subtype plays a crucial role in the ability to perceive pain s