Zobrazeno 1 - 10
of 887
pro vyhledávání: '"D, Chow"'
Autor:
Shelley Warner, Luciana Lerendegui, Monica D. Chow, David Lasko, Miguel Castellan, Felipe Pedroso
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 109, Iss , Pp 102856- (2024)
Introduction: Cloacal exstrophy is a rare birth defect that affects both the genitourinary and gastrointestinal tract, with an estimated incidence between 1:200,000 and 1:400,000 live births. The exact mechanism that leads to this defect is still unk
Externí odkaz:
https://doaj.org/article/f4d3447278224f6e9bb2f8ed68eb18fc
Autor:
Seok-Jin Heo, Lauren D. Enriquez, Scot Federman, Amy Y. Chang, Rachel Mace, Kaivalya Shevade, Phuong Nguyen, Adam J. Litterman, Shawn Shafer, Laralynne Przybyla, Eric D. Chow
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-20 (2024)
Abstract CRISPR genome editing approaches theoretically enable researchers to define the function of each human gene in specific cell types, but challenges remain to efficiently perform genetic perturbations in relevant models. In this work, we devel
Externí odkaz:
https://doaj.org/article/5f026eebf6b34406bec636b6eb2f851a
Autor:
Jennifer S. Chen, Michael J. Murphy, Katelyn Singh, Alice Wang, Ryan D. Chow, Sa Rang Kim, Jeffrey M. Cohen, Christine J. Ko, William Damsky
Publikováno v:
JID Innovations, Vol 3, Iss 4, Pp 100189- (2023)
Acral dermatoses, including hyperkeratotic palmoplantar eczema (HPE), palmoplantar psoriasis (PP), and mycosis fungoides palmaris et plantaris (MFPP), can be challenging to diagnose clinically and histopathologically. In this setting, cytokine biomar
Externí odkaz:
https://doaj.org/article/c84df0b20401449bb6e498fec9e0e197
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Autor:
Madison S Strine, Wesley L Cai, Jin Wei, Mia Madel Alfajaro, Renata B Filler, Scott B Biering, Sylvia Sarnik, Ryan D Chow, Ajinkya Patil, Kasey S Cervantes, Clayton K Collings, Peter C DeWeirdt, Ruth E Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G Doench, Patrick D Hsu, Cigall Kadoch, Qin Yan, Craig B Wilen
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002097 (2023)
Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of Coronavirus Disease 2019 (COVID-19). We previously performed a genome-wi
Externí odkaz:
https://doaj.org/article/c10dd58b10dd439eb9610eccf28fbb91
Autor:
Lei Peng, Yingxia Hu, Madeleine C. Mankowski, Ping Ren, Rita E. Chen, Jin Wei, Min Zhao, Tongqing Li, Therese Tripler, Lupeng Ye, Ryan D. Chow, Zhenhao Fang, Chunxiang Wu, Matthew B. Dong, Matthew Cook, Guilin Wang, Paul Clark, Bryce Nelson, Daryl Klein, Richard Sutton, Michael S. Diamond, Craig B. Wilen, Yong Xiong, Sidi Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Despite effective vaccines against SARS-CoV-2, therapeutic options such as anti-virals and neutralizing antibodies are critical in treating disease, especially given the breakthrough infections of emerging VOCs. Here, Peng et al. generate two potent
Externí odkaz:
https://doaj.org/article/3c2da467436042e1868fd384b454c96c
Autor:
Jaewon Song, Ryan D Chow, Mario A Peña-Hernández, Li Zhang, Skylar A Loeb, Eui-Young So, Olin D Liang, Ping Ren, Sidi Chen, Craig B Wilen, Sanghyun Lee
Publikováno v:
PLoS Biology, Vol 20, Iss 10, p e3001805 (2022)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is mediated by the entry receptor angiotensin-converting enzyme 2 (ACE2). Although attachment factors and coreceptors facilitating entry are extensively studied, cellular entry fa
Externí odkaz:
https://doaj.org/article/9ca0a77538664cbb885e8018fda703f5
Autor:
Salahuddin Nasir, Moustafa Abou Areda, Elise L. Ma, Robert D. Chow, Avelino Verceles, Carol Chiung-Hui Peng
Publikováno v:
Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 1, Pp 147-151 (2021)
A 21-year-old male presented with a 2-week history of nausea and non-bloody, non-bilious vomiting, accompanied by diffuse chronic myalgia. The patient endorsed headaches, dizziness, and diplopia that had started one day prior to admission. The patien
Externí odkaz:
https://doaj.org/article/ee4ae199307443ccbb5b7b92e63c5e16
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Age is one of the strongest risk factors for severe illness from COVID-19. By integrating human lung transcriptomes with experimental data on SARS-CoV-2, the authors pinpoint specific age-associated factors that could contribute to the heightened sev
Externí odkaz:
https://doaj.org/article/1ac48135f6d342e19f2405cc2d35983e
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Purpose(1) To determine the impact of transcranial direct current stimulation (tDCS) applied alone or combined with other therapies on the recovery of motor function after stroke and (2) To determine tDCS dosage effect.MethodsRandomized controlled tr
Externí odkaz:
https://doaj.org/article/465bae1207034a66813def147d9ba2a2
Publikováno v:
Case Reports in Medicine, Vol 2022 (2022)
Edema resulting from the initiation of insulin therapy or intensification of glycemic control is a rare and under-recognized complication. In this report, we present a case of a 46-year-old patient with insulin-dependent diabetes mellitus (IDDM) who
Externí odkaz:
https://doaj.org/article/54feaace598b48ccb34c20db76e39e7c