Zobrazeno 1 - 10
of 187
pro vyhledávání: '"D, Belke"'
Smoothelin-like 1 knockout mice display sex-dependent alterations in blood flow and cardiac function
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 101:27-40
Smoothelin-like 1 (SMTNL1) modulates the contractile performance of smooth muscle and thus has a key role in vascular homeostasis. Elevated vascular tone, recognized as a contributor to the development of progressive cardiac dysfunction, was previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d485a5e039cdbab594065dec357e55f
https://doi.org/10.1139/cjpp-2022-0172
https://doi.org/10.1139/cjpp-2022-0172
Autor:
Holly E.M. Mewhort, MD, PhD, Daniyil A. Svystonyuk, BSc, Jeannine D. Turnbull, BSc, Guoqi Teng, PhD, Darrell D. Belke, PhD, David G. Guzzardi, BSc, Daniel S. Park, BSc, Sean Kang, BSc, Morley D. Hollenberg, MD, PhD, Paul W.M. Fedak, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 4, Pp 450-464 (2017)
Structural cardiac remodeling after ischemic injury can induce a transition to heart failure from progressive loss of cardiac function. Cellular regenerative therapies are promising but face significant translational hurdles. Tissue extracellular mat
Externí odkaz:
https://doaj.org/article/cf90dedf8ce14b09a6a5fae040d08d80
Autor:
Loryn J. Bohne, Hailey J. Jansen, Tristan W. Dorey, Irene M. Daniel, K. Lockhart Jamieson, Darrell D. Belke, Megan D. McRae, Robert A. Rose
Publikováno v:
JACC: Basic to Translational Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80418a540981d35903a7c96190ae1897
https://doi.org/10.1016/j.jacbts.2023.01.005
https://doi.org/10.1016/j.jacbts.2023.01.005
Autor:
Shenghua Zhou, Yuting Cui, Hao Yin, Zhihan Tang, Yu Gui, Shi Tai, Darrell D. Belke, Binjie Yan, Xi-Long Zheng, Yanan Guo, Juan Peng
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:67-86
Objective: PCSK9 (proprotein convertase subtilisin/kexin type 9) plays a critical role in cholesterol metabolism via the PCSK9–LDLR (low-density lipoprotein receptor) axis in the liver; however, evidence indicates that PCSK9 directly contributes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7eeba18accb7a866f2578d9821a0df
https://doi.org/10.1161/atvbaha.121.316902
https://doi.org/10.1161/atvbaha.121.316902
Autor:
Aru Narendran, Aarthi Jayanthan, Darrell D. Belke, Wayne R. Giles, Satbir Thakur, Mohit Jain, Umberto Banderali
Publikováno v:
Current Eye Research. 47:426-435
PURPOSE Retinoblastoma is the most frequent intraocular cancer in children. It is also one of the most common causes for enucleation and carries a significant morbidity rate in affected individuals. Hence, studies on its pathophysiological and growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353d760ae89e4c00cac5181f76a482e3
https://doi.org/10.1080/02713683.2021.1988982
https://doi.org/10.1080/02713683.2021.1988982
Autor:
Andreas Brodehl, Darrell D Belke, Lauren Garnett, Kristina Martens, Nelly Abdelfatah, Marcela Rodriguez, Catherine Diao, Yong-Xiang Chen, Paul M K Gordon, Anders Nygren, Brenda Gerull
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174019 (2017)
BACKGROUND:Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder leading to ventricular arrhythmias and heart failure, mainly as a result of mutations in cardiac desmosomal genes. Desmosomes are cell-cell junctions mediating adhesion of
Externí odkaz:
https://doaj.org/article/218f18dcd14b44eabc6f22086f51cecc
Autor:
V. Vasanthan, A Fatehi Hassanabad, D. Belke, G. Teng, D. Dutta, J. Turnbull, J. Deniset, P. Fedak
Publikováno v:
Canadian Journal of Cardiology. 38:S211-S212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467c9a2c66c834d9494dfcd1d63d200e
https://doi.org/10.1016/j.cjca.2022.08.195
https://doi.org/10.1016/j.cjca.2022.08.195
Autor:
A. Jadli, N. Ballasy, K. Gomes, C. Mackay, M. Meechem, M. Wijesuriya, D. Belke, P. Fedak, V. Patel
Publikováno v:
Canadian Journal of Cardiology. 38:S216-S217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0f5140fa40a71313700db17d36fbe98
https://doi.org/10.1016/j.cjca.2022.08.201
https://doi.org/10.1016/j.cjca.2022.08.201
Autor:
Anshul S Jadli, Noura Ballasy, Karina Gomes, Cameron Mackay, Megan Meechem, Tishani Methsala Wijesuriya, Darrell D Belke, Paul Fedak, Vaibhav B Patel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: Thoracic aortic aneurysm (TAA) involves extracellular matrix (ECM) remodeling of the aortic wall, leading to reduced biomechanical support with risk of aortic dissection and rupture. Elusive pathophysiology of initiation and progression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f23d9aa2f67e907efe2a09b8e7c9f10
https://doi.org/10.1161/atvb.42.suppl_1.348
https://doi.org/10.1161/atvb.42.suppl_1.348
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5778d4437fae2147c0f30607ae32015e
https://doi.org/10.1096/fasebj.2022.36.s1.r2908
https://doi.org/10.1096/fasebj.2022.36.s1.r2908