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Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women

Autor: D Baylink, Clifford J. Rosen, Richard L. Prince, Amanda Devine, S Mohan

Publikováno v: Scopus-Elsevier

Insulin-like growth factor I (IGF-I) is a critical factor in the regulation of various physiologic effects, including bone formation and protein metabolism. Nutrient intake is a main regulator of circulating IGF-I. The relation of zinc status and IGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884cdb9934a4134e50bcf93d4f841dd3
https://doi.org/10.1093/ajcn/68.1.200

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A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group

Autor: C H, Chesnut, S, Silverman, K, Andriano, H, Genant, A, Gimona, S, Harris, D, Kiel, M, LeBoff, M, Maricic, P, Miller, C, Moniz, M, Peacock, P, Richardson, N, Watts, D, Baylink

Publikováno v: The American journal of medicine. 109(4)

We conducted a 5-year, double-blind, randomized, placebo-controlled study to determine whether salmon calcitonin nasal spray reduced the risk of new vertebral fractures in postmenopausal women with osteoporosis.A total of 1,255 postmenopausal women w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::623caea416a51f1ae530632cbecd63bc
https://pubmed.ncbi.nlm.nih.gov/10996586

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Concentrations of insulin-like growth factor (IGF)-I, -II, and IGF binding protein-4, and -5 in human bone cell conditioned medium do not change with age

Autor: Reinhard Ziegler, D Baylink, E.M Schuster, Ingo J. Diel, Johannes Pfeilschifter, T Klöppinger, S Balbach, S Mohan, Hanadi Bismar

Publikováno v: Mechanisms of ageing and development. 117(1-3)

We examined the effects of age on the secretion of insulin-like growth factor (IGF)-I, -II, and IGF binding protein-4, and -5 in long-term bone cell cultures from 71 female donors, aged 28-79 years. Our results suggest that under basal conditions, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5b5cab0439acaae0e3f4b8f51c018a
https://pubmed.ncbi.nlm.nih.gov/10958927

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Transforming Growth Factor Beta Mediates the Estrogen Induced Inhibition of Umr106 Cell Growth

Autor: T. K. Gray, T. Linkhart, Barbara D. Lipes, D. Baylink, S. Mohan

Publikováno v: Connective Tissue Research. 20:23-32

A mitogenic response to transforming growth factor beta (TGF) occurred in the UMR106 cells cultured in serum-free medium and exposed serially to estradiol and TGF. This mitogenic response was lost when insulin was removed from the medium. TGF inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed9f5b04d191d7115d4b52388947bf4
https://doi.org/10.3109/03008208909023871

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