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Akademický článek
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Autor:
Maria Victoria Silva Elipe, Kyle D. Baucom, Derek B. Brown, Kyle Quasdorf, Seb Caille, James I. Murray
Publikováno v:
The Journal of Organic Chemistry. 87:1977-1985
The ipso nitration of aryl boronic acid derivatives has been developed using fuming nitric acid as the nitrating agent. This facile procedure provides efficient and chemoselective access to a variety of aromatic nitro compounds. While several activat
Autor:
Andrew Cosbie, Kyle D. Baucom, Seb Caille, Maria Victoria Silva Elipe, Kyle Quasdorf, James I. Murray
Publikováno v:
Organic Process Research & Development. 24:1523-1530
During development of a radical benzylic bromination, observation of polymerized by-products and variation in isolated yields warranted an in-depth mechanistic investigation to ensure process under...
Autor:
Jo Anna Robinson, Ayman Allian, Jan Riedel, Michael T. Corbett, Kyle D. Baucom, Wendy Chen, Sheng Cui, Derek B. Brown, Elçin Içten, Parth Patel, Michael A. Lovette, Matthew G. Beaver, Tawnya G. Flick, Alicia Zeng, Xianqing Shi, Ning Yang, Andrew T. Parsons, Shawn D. Walker
Publikováno v:
Organic Process Research & Development. 24:490-499
The development and kilogram-scale demonstration of an improved process for the synthesis of the epoxyketone warhead of carfilzomib is described. Critical to the success of this process was: (1) de...
Publikováno v:
Psychoanalytic Psychotherapy. 32:368-384
This study examined therapist technique and patient change in emotional experiencing and defense mechanisms in the successful and unsuccessful long-term psychoanalytic treatments of two male patients. Two consecutive sessions every 6 months were anal
Akademický článek
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Autor:
Markus Etzkorn, Daniel S. Jones, Maria del Rosario I. Amado Sierra, Amy D. Baucom, Andria D. Harris
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 12, Pp o2270-o2270 (2008)
The title compound, C10H12O2, was synthesized as a candidate for further functionalization. The asymmetric unit comprises two independent molecules, both of which are situated on a center of symmetry. Both molecules are involved in a network of hydro
Externí odkaz:
https://doaj.org/article/e795a30072fb4a11aed561090b165ca2
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 7, Pp o1284-o1284 (2008)
The title compound, C12H8BrN, was prepared as a starting material for a Suzuki cross-coupling reaction with a pinacol ester. The torsion angle about the ring–methylene C—C bond is 30.7 (3)°, such that the N atom is displaced by 1.174 (4) Å from
Externí odkaz:
https://doaj.org/article/58715a240f1a42bc850270d17036f354
Publikováno v:
Organic Letters. 18:560-563
An operationally efficient CDI mediated tandem coupling and cyclization reaction to generate [1,2,4]triazolo[4,3-a]pyridines has been reported. The reaction conditions and scope were investigated, and the methodology was demonstrated in batch mode as
Kniha
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