Zobrazeno 1 - 10
of 108
pro vyhledávání: '"D, Baubichon"'
Publikováno v:
Annales Pharmaceutiques Françaises. 62:247-252
Amongst organophosphate compounds, both pesticides and warfare neurotoxics are probably the most representative. These compounds are irreversible acetylcholinesterase inhibitors. Usual clinical signs observed after acute poisoning are mainly respirat
Publikováno v:
Annales pharmaceutiques francaises. 62(4)
Amongst organophosphate compounds, both pesticides and warfare neurotoxics are probably the most representative. These compounds are irreversible acetylcholinesterase inhibitors. Usual clinical signs observed after acute poisoning are mainly respirat
Publikováno v:
Toxicology Letters. 196:S245-S246
Autor:
P, Filliat, D, Baubichon, M F, Burckhart, I, Pernot-Marino, A, Foquin, C, Masqueliez, C, Perrichon, P, Carpentier, G, Lallement
Publikováno v:
Neurotoxicology. 20(4)
The effects of soman, a potent irreversible inhibitor of acetylcholinesterase, on central neuropathology in rats were studied in relation with subsequent spatial memory impairments. In a first step, it was found that, without treatment, neuropatholog
Publikováno v:
Neurotoxicology. 20(4)
Today, organophosphorus nerve agents are still considered as potential threats in both military or terrorism situations. These agents act as potent irreversible inhibitors of acetylcholinesterase in both central and peripheral nervous systems. Conven
Publikováno v:
Neurotoxicology. 19(6)
Stress due to forced swimming was recently shown to allow penetration of pyridostigmine (PYR) into the brain of mice. Accordingly, it was suggested that in troops exposed to emotional stress under conditions of war, as during the Gulf War, the BBB ma
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 316(10)
The objective of the present study was to evaluate the anticonvulsant and neuroprotective activities of propentofylline against soman, an irreversible acetylcholinesterase inhibitor. In a first step, the ability of propentofylline to inhibit in vitro
Publikováno v:
Neuroreport. 4(10)
In the present study we investigated the role of the cholinergic pathway in phosphoinositide metabolism activation observed during soman-induced convulsions. We thus studied the effect of atropine sulphate, a muscarinic antagonist (20 mg kg-1, i.p.),
Publikováno v:
Neurotoxicology. 13(4)
The effects of the organophosphate acetylcholinesterase (AChE) inhibitor soman were investigated on different receptors coupled to phosphoinositide (PPI) breakdown on hippocampal slices in vitro. We observed that muscarinic receptor subtypes M1 and M
Publikováno v:
Neurotoxicology. 13(3)
Extracellular acetylcholine (ACh) levels were determined, by intracranial microdialysis, in medial septum, amygdala and hippocampus (CA1, CA3, dentate gyrus) of rats during seizures induced by systemic administration of soman (pinacolyl methylphospho