Výsledky vyhledávání

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Real life rates of sustained virological response (SVR) and predictors of relapse following DAA treatment in genotype 3 (GT3) patients with advanced fibrosis/cirrhosis

Autor: Natalia Terreni, Massimiliano Copetti, Ruggero Losappio, Vincenzo Palmieri, Domenico Potenza, Giovanni Cenderello, D. Bacca, Giulio De Stefano, Alessandra Mangia, Rosanna Santoro, Fernando Sogari, Michele Mazzola, Nicola Minerva, Valeria Piazzola

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0200568 (2018)
PLoS ONE

Background Treatment of GT3 remains challenging compared to other genotypes. Aims To explore real life SVR rates and to identify predictors of virological failure across the most recently used Direct acting antiviral (DAA) regimens in a large cohort

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0f05693102060d62294d7e5b08e596
http://europepmc.org/articles/PMC6067691?pdf=render

Zobrazit plný text záznamu

Il28B Cc-Genotype Association with Hla-Dqb1*0301 Allele Increases the Prediction of Spontaneous HCV RNA Clearance in Thalassaemic HCV-Infected Patients

Autor: Rosanna Santoro, D. Bacca, Massimiliano Copetti, Ippazio Stefano, Roberto Sarli, Lazzaro Di Mauro, Michele Sacco, Alessandra Mangia, Leonardo Mottola, Valeria Piazzolla, D. Petruzzellis, G. Lotti, R. Clemente

Publikováno v: Antiviral Therapy. 16:1309-1316

Background A single nucleotide polymorphism (SNP), upstream of the IL28B gene has been recently associated with natural clearance of HCV. In a well-characterized cohort of patients with thalassaemia major exposed to the risk of acquiring HCV infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2b1c92631816a69b2d9923ec53b9df
https://doi.org/10.3851/imp1913

Zobrazit plný text záznamu

Limited use of interleukin 28B in the setting of response-guided treatment with detailed on-treatment virological monitoring

Autor: Massimiliano Copetti, Alexander J. Thompson, D. Bacca, D. Petruzzellis, John G. McHutchison, Rosanna Santoro, Nicola Minerva, Valeria Piazzolla, Alessandra Mangia, Leonardo Mottola

Publikováno v: Hepatology. 54:772-780

A single-nucleotide polymorphism upstream of the interleukin-28B (IL28B) gene is associated with pegylated interferon-alfa–induced viral clearance in hepatitis C virus (HCV) genotype 1 patients. Using a well-characterized cohort of patients randomi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7e00e1cb41b8b78fa9dcabc343194c
https://doi.org/10.1002/hep.24458

Zobrazit plný text záznamu

Ribavirin dosage in patients with HCV genotypes 2 and 3 who completed short therapy with peg-interferon α-2b and ribavirin

Autor: Angelo Andriulli, Valeria Piazzolla, Massimiliano Copetti, D. Bacca, Hans Verbaan, Vito Carretta, Helmer Ring-Larsen, O. Dalgard, Alessandra Mangia, Raffaele Cozzolongo, Leonardo Mottola, Nicola Minerva

Publikováno v: Alimentary Pharmacology & Therapeutics. 31:1346-1353

Aliment Pharmacol Ther 31, 1346–1353 Summary Background The optimal dose of ribavirin to be used in combination with Peg-IFN in patients with HCV genotypes 2 and 3 undergoing short treatment has not been established. Aim To explore the relationship

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc99c16c244e8c8bffc30582121489f1
https://doi.org/10.1111/j.1365-2036.2010.04290.x

Zobrazit plný text záznamu

Plný text ve formátu HTML

Determinants of relapse after a short (12 weeks) course of antiviral therapy and re-treatment efficacy of a prolonged course in patients with chronic hepatitis C virus genotype 2 or 3 infection

Autor: Raffaele Cozzolongo, Gaetano Scotto, Vito Carretta, Mario R. Romano, Francesco Vinelli, Alessandra Mangia, Angelo Andriulli, G.L. Ricci, Fernando Sogari, Ernesto Agostinacchio, Nicola Minerva, D. Bacca, D. Petruzzellis

Publikováno v: Hepatology. 49:358-363

In hepatitis C virus (HCV) genotypes 2 and 3 patients, the high rate of relapse after 12 to 16 weeks of antiviral therapy is the main concern for shortening treatment duration. This study was undertaken to delineate predictors of relapse after short

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e56cbb6f47b249b5feec6fab28da54
https://doi.org/10.1002/hep.22679

Zobrazit plný text záznamu

Peginterferon Alfa-2b and Ribavirin for 12 vs. 24 Weeks in HCV Genotype 2 or 3

Autor: Fulvio Spirito, Angelo Andriulli, D. Bacca, Mario R. Romano, Gaetano Scotto, Marcello Persico, Fernando Sogari, G.L. Ricci, Nicola Minerva, Mauro Annese, Alessandra Mangia, Francesco Vinelli, Rosanna Santoro, Franco Zechini, Vito Carretta

Publikováno v: New England Journal of Medicine. 352:2609-2617

background We hypothesized that in patients with hepatitis C virus (HCV) genotype 2 or 3 in whom HCV RNA is not detectable after 4 weeks of therapy, 12 weeks of treatment is as effective as 24 weeks. methods A total of 283 patients were randomly assi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c43046b0ef065d08e8c77719a00e63
https://doi.org/10.1056/nejmoa042608

Zobrazit plný text záznamu

Treatment of patients with HCV infection with or without liver biopsy

Autor: Angelo Andriulli, D. D. Salvo, Giovanni De Maio, A. Iacobellis, A. Spadaccini, Gioacchino Leandro, Marcello Persico, D. Bacca, Francesco Ventrella, Alessandra Mangia

Publikováno v: Journal of Viral Hepatitis. 11:536-542

Expert consensus recommends liver biopsy before therapy for chronic hepatitis C. A cost effectiveness analysis suggested that the best strategy in the management of patients was to treat without biopsy. We compared therapy in patients who did, or did

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ab97ec7eaaa8fef9092ede365d7291
https://doi.org/10.1111/j.1365-2893.2004.00519.x

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání