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Antimicrobial Activity of Different Antimicrobial Peptides (AMPs) Against Clinical Methicillin-resistant Staphylococcus aureus (MRSA)

Autor: Wojciech Kamysz, Gianluca Morroni, Wally Baffone, D. Arzeni, Eleonora Ciandrini, Oscar Cirioni, Elżbieta Kamysz, Damian Neubauer, Raffaella Campana, Lucia Brescini

Publikováno v: Current Topics in Medicinal Chemistry. 18:2116-2126

Background: Antimicrobial research is being focused to look for more effective therapeutics against antibiotic-resistant infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In this direction, antimicrobial peptides (AMP) appear a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4976b9d888e028979bddb0add5a0988
https://doi.org/10.2174/1568026618666181022140348

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In vitro activity and in vivo efficacy of tigecycline alone and in combination with daptomycin and rifampin against Gram-positive cocci isolated from surgical wound infection

Autor: Carmela Silvestri, D. Arzeni, Mauro Provinciali, Fiorenza Orlando, Andrea Giacometti, Silvia Staffolani, Giulia Ganzetti, A. M. Offidani, Lucia Brescini, Roberto Ghiselli, Oscar Cirioni, Mario Guerrieri, Oriana Simonetti

Publikováno v: European Journal of Clinical Microbiology & Infectious Diseases. 31:1759-1764

The aim of this work was to determine the in vitro activity of tigecycline and its bactericidal effect for a large number of Gram-positive cocci, as well as to investigate its in vitro interaction with six clinically used antibiotics. In vivo, a woun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d90c5d111273ebac5880bd74d7f803
https://doi.org/10.1007/s10096-011-1498-1

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In vitroactivity of the lipopeptide derivative (Pal-lys-lys-NH2), alone and in combination with antifungal agents, against clinical isolates of dermatophytes

Autor: Wojciech Kamysz, E. Gabrielli, Elżbieta Kamysz, Francesco Barchiesi, A. M. Offidani, Sefora Castelletti, Giulia Ganzetti, Oscar Cirioni, D. Arzeni, Giorgio Scalise, Oriana Simonetti, Carmela Silvestri

Publikováno v: British Journal of Dermatology. 161:249-252

Summary Background An increasing number of antimycotics have become available for the treatment of dermatophytoses; however, there are reports suggesting recalcitrance to therapy or resistance of a dermatophyte against conventional treatment. Lipopep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63e5f7e1a80efee6abbcf5262b336c87
https://doi.org/10.1111/j.1365-2133.2009.09166.x

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In vitro activity of the synthetic lipopeptide PAL-Lys-Lys-NH2 alone and in combination with antifungal agents against clinical isolates of Cryptococcus neoformans

Autor: Elżbieta Kamysz, Alessandra Abbruzzetti, Giorgio Scalise, Alessandra Riva, D. Arzeni, Andrea Giacometti, Oscar Cirioni, Carmela Silvestri, Wojciech Kamysz, Francesco Barchiesi

Publikováno v: Peptides. 28:1509-1513

The in vitro activity of the lipopeptide PAL-Lys-Lys-NH(2) (PAL), alone or combined with either fluconazole (FLU) or amphotericin B (AMB), was investigated against 14 Cryptococcus neoformans isolates. PAL MICs ranged from 1.0 to 4.0 microg/ml. Fungic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba14ec3c34b218b64ef36b0b7d51c983
https://doi.org/10.1016/j.peptides.2007.07.010

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Effects of Caspofungin against Candida guilliermondii and Candida parapsilosis

Autor: Agnese Della Vittoria, D. Arzeni, Serena Tomassetti, Esther Manso, Francesco Barchiesi, Giorgio Scalise, Elisabetta Spreghini

Publikováno v: Antimicrobial Agents and Chemotherapy. 50:2719-2727

The in vitro activity of caspofungin (CAS) was investigated against 28 yeast isolates belonging to Candida albicans ( n = 5), Candida guilliermondii ( n = 10), and Candida parapsilosis ( n = 13). CAS MICs obtained by broth dilution and Etest methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c0decc1d0907383453e01238125730
https://doi.org/10.1128/aac.00111-06

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Comparison of the Fungicidal Activities of Caspofungin and Amphotericin B against Candida glabrata

Autor: D. Arzeni, Giorgio Scalise, Elisabetta Spreghini, Daniele Giannini, Serena Tomassetti, Francesco Barchiesi

Publikováno v: Antimicrobial Agents and Chemotherapy. 49:4989-4992

We investigated the fungicidal activity of caspofungin (CAS) and amphotericin B (AMB) against 16 clinical isolates of Candida glabrata . The minimum fungicidal concentrations (MFCs) of CAS were similar to those of AMB, ranging from 2.0 to >8.0 μg/ml

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc6799e7825c2b3b83596c1c7d61d77
https://doi.org/10.1128/aac.49.12.4989-4992.2005

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Caspofungin in Combination with Amphotericin B against Candida glabrata

Autor: Elisabetta Spreghini, Francesco Barchiesi, Michael G. Rinaldi, D. Arzeni, Daniele Giannini, Gianfranco Greganti, Giorgio Scalise, Annette W. Fothergill

Publikováno v: Antimicrobial Agents and Chemotherapy. 49:2546-2549

The effects of caspofungin combined with amphotericin B were investigated with Candida glabrata . Although in vitro experiments showed an indifferent interaction, the combination regimen was the only therapeutic approach yielding organ sterilization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cff9871299a6063f91b9f3b81fc8b6
https://doi.org/10.1128/aac.49.6.2546-2549.2005

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Epidemiology of onychomycosis and paronychia in the area of ANCONA (ITALY) over a period of 5 years

Autor: D. Arzeni, A. M. Offidani, Francesco Barchiesi, Andreina Cellini, Maria Luisa Bernardini, Oriana Simonetti

Publikováno v: Mycopathologia. 158:271-274

We retrospectively evaluated the epidemiology of onychomycosis and/or paronychia in 172 patients attending the Clinic of Dermatology and Venereology over a 5 year period. Although yeast isolates, belonging to the Candida species, represented the most

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f27021851d5678f6e805c7074c98007
https://doi.org/10.1007/s11046-004-9615-7

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Autor: Giorgio Scalise, Andreina Cellini, Andrea Giacometti, D. Arzeni, Francesca Caselli, Oriana Simonetti, A. M. Offidani, L Falconi Di Francesco, Francesco Barchiesi

Publikováno v: Mycopathologia. 149:117-121

Forty-six isolates of Candida parapsilosis, each from a single patient, were collected from July 1993 through March 1999 at the University of Ancona Hospitals and Clinics. Twenty-eight strains were isolated from superficial lesioned sites, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68636ef9c750a30b5be2aa200db2c2bf
https://doi.org/10.1023/a:1007279213485

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In-vitro interactions of itraconazole with flucytosine against clinical isolates of Cryptococcus neoformans

Autor: Francesco Barchiesi, D. Arzeni, Andrea Giacometti, Domenico Gallo, Giorgio Scalise, Luigi Falconi Di Francesco, Francesca Caselli

Publikováno v: Journal of Antimicrobial Chemotherapy. 44:65-70

Treatment failures can occur in AIDS patients infected with Cryptococcus neoformans, despite aggressive antifungal therapy. Combination regimens with additive or synergic drugs could provide additional options for treating cryptococcosis. We studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e75343f6f19318a98e6d03cd2ea8625
https://doi.org/10.1093/jac/44.1.65

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