Modulation of prion protein expression through cryptic splice site manipulation

Autor: Gentile, Juliana E., Corridon, Taylor L., Mortberg, Meredith A., D’Souza, Elston Neil, Whiffin, Nicola, Minikel, Eric Vallabh, Vallabh, Sonia M.

Publikováno v: In Journal of Biological Chemistry August 2024 300(8)

Modulation of prion protein expression through cryptic splice site manipulation.

Autor: Gentile JE; McCance Center for Brain Health and Department of Neurology, Massachusetts General Hospital, Boston, MA 02114.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Corridon TL; McCance Center for Brain Health and Department of Neurology, Massachusetts General Hospital, Boston, MA 02114.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Mortberg MA; McCance Center for Brain Health and Department of Neurology, Massachusetts General Hospital, Boston, MA 02114.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142., D'Souza EN; Big Data Institute and Centre for Human Genetics, University of Oxford, Oxford OX3 7LF, UK., Whiffin N; Big Data Institute and Centre for Human Genetics, University of Oxford, Oxford OX3 7LF, UK.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA., Minikel EV; McCance Center for Brain Health and Department of Neurology, Massachusetts General Hospital, Boston, MA 02114.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Vallabh SM; McCance Center for Brain Health and Department of Neurology, Massachusetts General Hospital, Boston, MA 02114.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 19. Date of Electronic Publication: 2023 Dec 19.