Platelet toll-like receptors in thromboinflammation

Autor: D' Atri Lp, Schattner M

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Besides their undiscussed role in hemostasis and thrombosis, platelets are also key effector cells capable of assisting and modulating inflammatory reactions and immune responses. Platelets play a sentinel role in immune surveillance by recognizing d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329171b6ff18fadd9f06b6000e363bd9
https://pubmed.ncbi.nlm.nih.gov/28410150

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Activation of toll-like receptors 2 and 4 on CD34 ⁺ cells increases human megakaryo/thrombopoiesis induced by thrombopoietin.

Autor: D'Atri LP; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina., Rodríguez CS; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina., Miguel CP; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina., Pozner RG; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina., Ortiz Wilczyñski JM; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina., Negrotto S; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina., Carrera-Silva EA; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina., Heller PG; Institute of Medical Research Dr. Alfredo Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.; Department of Hematology Research, National Scientific and Technical Research Council (CONICET), University of Buenos Aires, Institute of Medical Research (IDIM), Buenos Aires, Argentina., Schattner M; Laboratory of Experimental Thrombosis, Institute of Experimental Medicine-CONICET-National Academy of Medicine, Buenos Aires, Argentina.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2019 Dec; Vol. 17 (12), pp. 2196-2210. Date of Electronic Publication: 2019 Sep 13.

Mediators and molecular pathways involved in the regulation of neutrophil extracellular trap formation mediated by activated platelets.

Autor: Carestia A; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., Kaufman T; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., Rivadeneyra L; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., Landoni VI; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., Pozner RG; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., Negrotto S; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., D'Atri LP; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., Gómez RM; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina., Schattner M; Laboratory of Experimental Thrombosis and Laboratory of the Inflammatory Process, Institute of Experimental Medicine-CONICET, National Academy of Medicine. Buenos Aires, Argentina; Biotechnology and Molecular Biology Institute, CONICET-UNLP, La Plata, Argentina mschattner@hotmail.com.

Publikováno v: Journal of leukocyte biology [J Leukoc Biol] 2016 Jan; Vol. 99 (1), pp. 153-62. Date of Electronic Publication: 2015 Aug 28.

Acidosis downregulates platelet haemostatic functions and promotes neutrophil proinflammatory responses mediated by platelets.

Autor: Etulain J; Thrombosis I Laboratory, National Academy of Medicine, CONICET, Buenos Aires, Argentina., Negrotto S, Carestia A, Pozner RG, Romaniuk MA, D'Atri LP, Klement GL, Schattner M

Publikováno v: Thrombosis and haemostasis [Thromb Haemost] 2012 Jan; Vol. 107 (1), pp. 99-110. Date of Electronic Publication: 2011 Dec 08.