A phospholipid mimetic targeting LRH-1 ameliorates colitis

Autor: Mays, Suzanne G., D’Agostino, Emma H., Flynn, Autumn R., Huang, Xiangsheng, Wang, Guohui, Liu, Xu, Millings, Elizabeth J., Okafor, C. Denise, Patel, Anamika, Cato, Michael L., Cornelison, Jeffery L., Melchers, Diana, Houtman, René, Moore, David D., Calvert, John W., Jui, Nathan T., Ortlund, Eric A.

Publikováno v: In Cell Chemical Biology 21 July 2022 29(7):1174-1186

Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition

Autor: Cornelison, Jeffery L., Cato, Michael L., Johnson, Alyssa M., D'Agostino, Emma H., Melchers, Diana, Patel, Anamika B., Mays, Suzanne G., Houtman, René, Ortlund, Eric A., Jui, Nathan T.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 15 August 2020 30(16)

Differential Modulation of Nuclear Receptor LRH‑1 through Targeting Buried and Surface Regions of the Binding Pocket.

Autor: Cato, Michael L., Cornelison, Jeffery L., Spurlin, Racheal M., Courouble, Valentine V., Patel, Anamika B., Flynn, Autumn R., Johnson, Alyssa M., Okafor, C. Denise, Frank, Filipp, D'Agostino, Emma H., Griffin, Patrick R., Jui, Nathan T., Ortlund, Eric A.

Publikováno v: Journal of Medicinal Chemistry; 5/12/2022, Vol. 65 Issue 9, p6888-6902, 15p

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Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors.

Autor: D'Agostino EH; Department of Biochemistry and Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Flynn AR; Department of Biochemistry and Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Cornelison JL; Department of Biochemistry and Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Mays SG; Department of Biochemistry and Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Patel A; Department of Biochemistry and Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Jui NT; Department of Biochemistry and Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Ortlund EA; Department of Biochemistry and Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Nov 21; Vol. 11 (3), pp. 365-370. Date of Electronic Publication: 2019 Nov 21 (Print Publication: 2020).