Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cytotoxicity, Immunologic/*immunology"'
Autor:
Susannah Williams, Alberto Nassi, Philippe Hantraye, Aurore Bugi, Marie Michael, Sophie Lecourtois, Caroline Jan, Emanuele Cozzi, Antoine Blancher, Anselme L. Perrier, Romina Aron Badin, Marta Vadori
Publikováno v:
Nature Communications
Nature Communications, In press, 10, pp.4357. ⟨10.1038/s41467-019-12324-0⟩
Nature Communications, Nature Publishing Group, 2019, 10, pp.4357. ⟨10.1038/s41467-019-12324-0⟩
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, In press, 10, pp.4357. ⟨10.1038/s41467-019-12324-0⟩
Nature Communications, Nature Publishing Group, 2019, 10, pp.4357. ⟨10.1038/s41467-019-12324-0⟩
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Cell therapy products (CTP) derived from pluripotent stem cells (iPSCs) may constitute a renewable, specifically differentiated source of cells to potentially cure patients with neurodegenerative disorders. However, the immunogenicity of CTP remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588ddf3c7a3ff145b06c0db45b983fe1
https://hal-cea.archives-ouvertes.fr/cea-02997553
https://hal-cea.archives-ouvertes.fr/cea-02997553
Autor:
Nicolet, Benoît P, Guislain, Aurélie, van Alphen, Floris P J, Gomez-Eerland, Raquel, Schumacher, Ton N M, van den Biggelaar, Maartje, Wolkers, Monika C, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6686. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6686-6696. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6686-6696. National Academy of Sciences
Cytotoxic CD8 + T cells can effectively kill target cells by producing cytokines, chemokines, and granzymes. Expression of these effector molecules is however highly divergent, and tools that identify and preselect CD8 + T cells with a cytotoxic expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73343329c79085b81488bf22e53a8251
https://hdl.handle.net/1874/411318
https://hdl.handle.net/1874/411318
Autor:
James P. Di Santo, Sophia Maschalidi, Fernando E. Sepulveda, Geneviève de Saint Basile, Gaël Ménasché, Alain Fischer, Christian A. J. Vosshenrich, Mathieu Kurowska, Alexandrine Garrigue
Publikováno v:
Blood
Blood, American Society of Hematology, 2015, 125 (9), pp.1427-34. ⟨10.1182/blood-2014-09-602946⟩
Blood, 2015, 125 (9), pp.1427-34. ⟨10.1182/blood-2014-09-602946⟩
Blood, American Society of Hematology, 2015, 125 (9), pp.1427-1434. ⟨10.1182/blood-2014-09-602946⟩
Blood, American Society of Hematology, 2015, 125 (9), pp.1427-34. ⟨10.1182/blood-2014-09-602946⟩
Blood, 2015, 125 (9), pp.1427-34. ⟨10.1182/blood-2014-09-602946⟩
Blood, American Society of Hematology, 2015, 125 (9), pp.1427-1434. ⟨10.1182/blood-2014-09-602946⟩
International audience; The impairment of cytotoxic activity of lymphocytes disturbs immune surveillance and leads to the development of hemophagocytic lymphohistiocytic syndrome (HLH). Although cytotoxic T lymphocyte (CTL) control of HLH development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c775810d37acc20400567fa4d50a93ae
https://doi.org/10.1182/blood-2014-09-602946
https://doi.org/10.1182/blood-2014-09-602946
Autor:
Eckhard Wolf, Anjan K. Bongoni, Robert Rieben, Gisella Puga Yung, David Ayares, Mihai A. Constantinescu, Amandine Pradier, Riccardo Sfriso, Natacha Madelon, Jorg Dieter Seebach, Maria Papaserafeim, Nikolai Klymiuk, David Kiermeir, Andrea Bähr, Esther Voegelin, Hansjörg Jenni
Publikováno v:
Xenotransplantation, Vol. 25, No 1 (2018)
Background: In pig-to-human xenotransplantation, interactions between human natural killer (NK) cells and porcine endothelial cells (pEC) are characterized by recruitment and cytotoxicity. Protection from xenogeneic NK cytotoxicity can be achieved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713152d11f203d854205e5a2f6ce5b86
Autor:
Cedric Bandelier, Laure Valloton, Pierre-Yves Martin, Yannick Avila, Leo Buhler, Sylvie Ferrari-Lacraz, Casimir de Rham, Giuseppe Pantaleo, Manuel Pascual, Karine Hadaya, Jean Villard
Publikováno v:
Clinical Immunology, Vol. 137, No 2 (2010) pp. 250-260
Polyclonal rabbit anti-thymocyte globulin (rATG) is widely used in solid organ transplantation (SOT) as induction therapy or to treat corticosteroid-resistant rejection. In vivo, the effect of rATG on natural killer (NK) cells has not been studied. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329cd6d2645ab6405f6a63b67664ffda
https://doi.org/10.1016/j.clim.2010.07.004
https://doi.org/10.1016/j.clim.2010.07.004
Autor:
Balimkiz Senman, E. Ashley Moseman, Michael P Flynn, Philip W. Askenase, Silke Paust, Marian Szczepanik, Bao-Zhong Wang, Amalio Telenti, Harvinder S. Gill, Ulrich H. von Andrian, Richard W. Compans
Publikováno v:
Nature immunology
Nature immunology, vol. 11, no. 12, pp. 1127-1135
Nature immunology, vol. 11, no. 12, pp. 1127-1135
Hepatic natural killer (NK) cells mediate antigen-specific contact hypersensitivity (CHS) in mice deficient in T cells and B cells. We report here that hepatic NK cells, but not splenic or naive NK cells, also developed specific memory of vaccines co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8422915f39066e539773e18185d1bd15
Autor:
Paul W. H. I. Parren, Inger S. Nijhof, Tuna Mutis, Yannis Morel, Henk M. Lokhorst, Pascale Andre, Berris van Kessel, Niels W.C.J. van de Donk, Jeroen J. Lammerts van Bueren
Publikováno v:
Haematologica, 100(2), 263-268. Ferrata Storti Foundation
Nijhof, I S, Lammerts van Bueren, J J, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W, Parren, P W & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Nijhof, I S, van Bueren, J J L, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W C J, Parren, P W H I & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Nijhof, I S, Lammerts van Bueren, J J, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W, Parren, P W & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Nijhof, I S, van Bueren, J J L, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W C J, Parren, P W H I & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Despite recent treatment improvements, multiple myeloma remains an incurable disease. Since antibody-dependent cell-mediated cytotoxicity is an important effector mechanism of daratumumab, we explored the possibility of improving daratumumab-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caef03c61a2f59fe0389a1b8d611779c
https://research.vumc.nl/en/publications/c13eee17-fa2a-4fa7-8efe-a25eee378540
https://research.vumc.nl/en/publications/c13eee17-fa2a-4fa7-8efe-a25eee378540
Autor:
Sachiko Okamoto, Sacha Gnjatic, Lloyd J. Old, Kunle Odunsi, Hiroshi Shiku, Protul Shrikant, Junko Matsuzaki, Immanuel F. Luescher, Junichi Mineno, Takemasa Tsuji
Publikováno v:
Scientific Reports, vol. 5, pp. 14896
Scientific Reports
Scientific Reports
Tumor antigen-specific CD4+ T cells generally orchestrate and regulate immune cells to provide immune surveillance against malignancy. However, activation of antigen-specific CD4+ T cells is restricted at local tumor sites where antigen-presenting ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283b68bfd7b485f9797e49109efb088e
https://serval.unil.ch/notice/serval:BIB_3E00A45B9B00
https://serval.unil.ch/notice/serval:BIB_3E00A45B9B00
Autor:
Vermijlen, David, Brouwer, Margreet, Donner, Catherine, Liesnard, Corinne, Tackoen, Marie, Van Rysselberge, Michel, Twite, Nicolas, Goldman, Michel, Marchant, Arnaud, Willems, Fabienne
Publikováno v:
The Journal of experimental medicine, 207 (4
The fetus and infant are highly susceptible to viral infections. Several viruses, including human cytomegalovirus (CMV), cause more severe disease in early life compared with later life. It is generally accepted that this is a result of the immaturit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2101::643040196419ef6c0712795e1c7b3cf9
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/116305
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/116305
Publikováno v:
Xenotransplantation, Vol. 16, No 1 (2009) pp. 19-26
BACKGROUND: Human natural killer (NK) cell-mediated cytotoxicity represents a hurdle in pig-to-human xenotransplantation. It was previously reported that the expression of human major histocompatibility complex class I molecules, including HLA-B27, -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d3b221b12f01882c82385c8a8d2510
https://pubmed.ncbi.nlm.nih.gov/19243557
https://pubmed.ncbi.nlm.nih.gov/19243557