Zobrazeno 1 - 10
of 482
pro vyhledávání: '"Cytotoxic T lymphocyte antigen-4"'
Autor:
Y. Moskalenko
Publikováno v:
Regulatory Mechanisms in Biosystems, Vol 15, Iss 1, Pp 83-91 (2024)
Immune checkpoint inhibitors have opened up new possibilities in clinical oncology. Monoclonal antibodies have shown their high clinical efficiency. They block CTLA-4, PD-1, and PD-L1 receptors and activate the immune response. Many patients have sta
Externí odkaz:
https://doaj.org/article/80400fda34464c32807af8c0299bc9cf
Autor:
ZHENG Yang, Patiguli Aerxiding
Publikováno v:
Zhongguo linchuang yanjiu, Vol 36, Iss 6, Pp 805-809 (2023)
Small cell lung cancer (SCLC) is a highly aggressive malignancy with rapid disease progression, easy recurrence in the short term and extremely poor prognosis. SCLC is recognized as a refractory disease by the National Cancer Institute. In recent yea
Externí odkaz:
https://doaj.org/article/74dd64da2e1541218a324fad85d57b94
Publikováno v:
International Journal of General Medicine, Vol Volume 16, Pp 1513-1525 (2023)
Lang Wang,1,2,* Zhiqi Zhang,1,3,* Xingxiang Chen,1 Fang Yu,4 Hai Huang,4 Xue Shen,4 Yujie Tan,4 Qingqing Wu4 1Department of Microbiology and Immunology, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, People’s Re
Externí odkaz:
https://doaj.org/article/e35abacb637f42838287b628cfb892d3
Publikováno v:
Indian Journal of Health Sciences and Biomedical Research KLEU, Vol 16, Iss 2, Pp 192-198 (2023)
The most frequent consequence of pregnancy is a miscarriage, which occurs when a pregnancy terminates before the fetus achieves viability. Fifteen percent of clinically confirmed pregnancies result in miscarriage, and overall reproductive losses are
Externí odkaz:
https://doaj.org/article/8fc74e746f5d45b0b75be74c7a9d50a8
Publikováno v:
Dental Journal, Vol 55, Iss 4, Pp 194-199 (2022)
Background: One of the benign salivary gland tumors is Warthin’s tumor, which is a benign tumor consisting of a papillary cystic structure covered by a double epithelial layer cells and lymphoid stroma with germinal center. Several cases have repor
Externí odkaz:
https://doaj.org/article/974d8d04c59c473098408de6ce6fc75d
Autor:
Ting-Wei Lin, Ya-Chiao Hu, Yao-Hsu Yang, Yin-Hsiu Chien, Ni-Chung Lee, Hsin-Hui Yu, Bor-Luen Chiang, Li-Chieh Wang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 3, Pp 545-548 (2022)
We reported a patient with autoimmunity (multiple sclerosis), immunodeficiency (hypogammaglobulinemia with severe infections), enteropathy (diarrhea with intestinal inflammation), splenomegaly, lymphadenopathy and lymphocytic infiltration of non-lymp
Externí odkaz:
https://doaj.org/article/40130c37e7684f4cbcf39547f0f4bff1
Autor:
Kun Hee Lee, So Jung Kim, Jin Seok Woo, Seung Yoon Lee, Jooyeon Jhun, Jeonghyeon Moon, Yoon Ju Jung, Mi-La Cho, Kyo Young Song
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAlthough tumor, node, metastasis (TNM) staging has been used for prognostic assessment of gastric cancer (GC), the prognosis may vary among patients with the same TNM stage. Recently, the TNM-Immune (TNM-I) classification staging system h
Externí odkaz:
https://doaj.org/article/869574abaed341f6951763c74306fce2
Autor:
Yuichiro Iwamoto, Tomohiko Kimura, Hideyuki Iwamoto, Junpei Sanada, Yoshiro Fushimi, Yukino Katakura, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundImmune checkpoint inhibitors (ICIs), such as cytotoxic T lymphocyte antigen-4 (CTLA-4) inhibitors, programmed cell death protein 1 (PD-1) inhibitors, and programmed cell death protein 1 ligand 1 (PD-L1) inhibitors, are often used to treat a
Externí odkaz:
https://doaj.org/article/d67aa2bc227f40018a0db8cfad481d6e
Autor:
Wu Wang, Xi Wang, Wenli Yang, Kai Zhong, Na He, Xuexia Li, Yanyang Pang, Zi Lu, Aiqun Liu, Xiaoling Lu
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Cytokine-induced killer cells induced with tumor antigen-pulsed dendritic cells (DC-CIK) immunotherapy is a promising strategy for the treatment of malignant tumors. However, itsefficacy isrestricted by the immunosuppression, whic
Externí odkaz:
https://doaj.org/article/281bbb81ffca4916990afe5d80e2d14d
Publikováno v:
Frontiers in Applied Mathematics and Statistics, Vol 8 (2022)
Anti CTLA-4 therapy is aimed at blocking the Cytotoxic T-lymphocyte antigen-4 (CTLA-4), a key cancer immunity cycle checkpoint. The mechanism of action of CTLA-4 may be described as a dynamic competition for the B7 ligand which, subsequently, interfe
Externí odkaz:
https://doaj.org/article/40dafde082c041508077a8aed1990c1e