Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Cytosine nucleoside"'
Autor:
Shuai Niu, Yi Liang, Wanying Yue, Yi Zhang, Junbiao Chang, Qingduan Wang, Huiping Chen, Ning Wang, Youmei Peng, Yan Zhang, Fang Ma, Xiang Jing
Publikováno v:
Genes & Genomics. 44:123-131
Previously, we published that 4′-azid-2′-deoxy-2′-fluorarabinoside (FNC), a novel cytosine nucleoside analog, has good anti-viral and anti-tumor activity. This study aimed to further explore the role and molecular mechanism of FNC in non-small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e1d329601deffce0598c283bf2963d
https://doi.org/10.1007/s13258-021-01179-9
https://doi.org/10.1007/s13258-021-01179-9
Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-11 (2021)
AIDS Research and Therapy
AIDS Research and Therapy
BackgroundDolutegravir (DTG) monotherapy results in virologic failure and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional mono- or dual therapy with a non-cytosine nucleoside analog (NA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf27c51342d1fa5b379efde0848c393
https://doaj.org/article/99325f8b0a7245c5bb8e6acf1a28eea3
https://doaj.org/article/99325f8b0a7245c5bb8e6acf1a28eea3
Publikováno v:
Drug Development Research. 81:274-282
In view of the potent anticancer activity of the d-arabino-configured cytosine nucleoside (ara-C), apioarabinofuranosyl pyrimidine nucleosides were designed and synthesized from d-ribose as starting material. The synthetic strategy signifies that tos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce108fd02b50a2084d441c4ebfdf7924
https://doi.org/10.1002/ddr.21613
https://doi.org/10.1002/ddr.21613
Background Dolutegravir (DTG) monotherapy results in unacceptable virologic failure rates and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional monotherapy, or functional dual therapy with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8c2b4059208fa0e690b29776aa10c2
https://doi.org/10.21203/rs.3.rs-74793/v1
https://doi.org/10.21203/rs.3.rs-74793/v1
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 224:117452
Nucleoside drugs are known for their remarkable anticancer and antiviral properties. The development of nucleoside drugs has attracted much attention and generated a great deal of research interest. β-L-cytidine and β-D-cytidine are a pair of cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4fd4ccbba45d1395936da887c4e966
https://doi.org/10.1016/j.saa.2019.117452
https://doi.org/10.1016/j.saa.2019.117452
Autor:
Kristin Freudenberg, Nadja Lindner, Sebastian Dohnke, Annette I. Garbe, Sonja Schallenberg, Karsten Kretschmer
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Front. Immunol. 9, DOI: 10.3389/fimmu.2018.00125 (2018)
Frontiers in Immunology
Front. Immunol. 9, DOI: 10.3389/fimmu.2018.00125 (2018)
Under physiological conditions, CD4(+) regulatory T (Treg) cells expressing the transcription factor Foxp3 are generated in the thymus [thymus-derived Foxp3(+) Treg (tTregs) cells] and extrathymically at peripheral sites [peripherally induced Foxp3(+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d08c696533f2dfc10eb2129dbf07fb
http://journal.frontiersin.org/article/10.3389/fimmu.2018.00125/full
http://journal.frontiersin.org/article/10.3389/fimmu.2018.00125/full
Autor:
Maria Camila Castro, Vu Nguyen, Colton J Tucker, Edwin DeJesus, Federico Hinestrosa, Beth Bryant, Charlotte-Paige Rolle
Publikováno v:
Open Forum Infectious Diseases
Background Dual dolutegravir (DTG)-containing regimens (DCRs) are currently approved for the treatment of antiretroviral (ARV) naïve and experienced patients with HIV-1 infection. DTG monotherapy has resulted in unacceptable rates of virologic failu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63883460f85653e9a67a633b6d36c713
https://doi.org/10.1093/ofid/ofz360.2164
https://doi.org/10.1093/ofid/ofz360.2164
Akademický článek
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Autor:
Ana Maria Oliveira-Brett, Ilanna C. Lopes, Liseta Lemos, Rafael M. Buoro, Silvia H.P. Serrano, Victor C. Diculescu
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The electrochemical behaviour of the cytosine nucleoside analogue and anti-cancer drug gemcitabine (GEM) was investigated at glassy carbon electrode, using cyclic, differential pulse and square wave voltammetry, in different pH supporting electrolyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3549d7685cedc8d4835dcafe7870f3a
https://doi.org/10.1016/j.bioelechem.2014.05.005
https://doi.org/10.1016/j.bioelechem.2014.05.005
Autor:
Varughese Alexander, Jungwon Choi, Sang Kook Lee, Jin-Hee Kim, Jayoung Song, Jinha Yu, Hyuk Woo Lee, Jung Hee Choi, Hea Ok Kim, Lak Shin Jeong
Publikováno v:
European Journal of Medicinal Chemistry. 83:208-225
Based on the potent anticancer activity of the D-arabino-configured cytosine nucleoside ara-C, novel 2′-substituted-4′-selenoarabinofuranosyl pyrimidines 3a–3u, comprising azido, fluoro, and hydroxyl substituents at C-2′ were designed, synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81ebb41445c97b348f21ec89332658e
https://doi.org/10.1016/j.ejmech.2014.06.031
https://doi.org/10.1016/j.ejmech.2014.06.031