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pro vyhledávání: '"Cytosine nucleoside"'
Akademický článek
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Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background Dolutegravir (DTG) monotherapy results in virologic failure and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional mono- or dual therapy with a non-cytosine nucleoside a
Externí odkaz:
https://doaj.org/article/99325f8b0a7245c5bb8e6acf1a28eea3
Autor:
Rolle, Charlotte-Paige1,2 (AUTHOR) crolle@oicorlando.com, Nguyen, Vu3 (AUTHOR), Hinestrosa, Federico1,3 (AUTHOR), DeJesus, Edwin1,3 (AUTHOR) edejesus@oicorlando.com
Publikováno v:
AIDS Research & Therapy. 5/3/2021, Vol. 18 Issue 1, p1-11. 11p.
Akademický článek
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Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-11 (2021)
AIDS Research and Therapy
AIDS Research and Therapy
BackgroundDolutegravir (DTG) monotherapy results in virologic failure and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional mono- or dual therapy with a non-cytosine nucleoside analog (NA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf27c51342d1fa5b379efde0848c393
https://doaj.org/article/99325f8b0a7245c5bb8e6acf1a28eea3
https://doaj.org/article/99325f8b0a7245c5bb8e6acf1a28eea3
Publikováno v:
The Journal of Physical Chemistry B. 126:7975-7980
A triplet excited state can lead to different DNA photolesions, especially in cytosine and its nucleoside/nucleotide as they are hotspots for DNA mutations. However, the triplet state generation mechanism is in controversy, and experimental evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d02f986b234b25ac360b67cf0326d8f
https://doi.org/10.1021/acs.jpcb.2c05865
https://doi.org/10.1021/acs.jpcb.2c05865
Background Dolutegravir (DTG) monotherapy results in unacceptable virologic failure rates and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional monotherapy, or functional dual therapy with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8c2b4059208fa0e690b29776aa10c2
https://doi.org/10.21203/rs.3.rs-74793/v1
https://doi.org/10.21203/rs.3.rs-74793/v1
Autor:
Rolle, Charlotte-Paige M1 (AUTHOR), Bryant, Beth1 (AUTHOR), Tucker, Colton J2 (AUTHOR), Castro, Maria Camila3 (AUTHOR), Nguyen, Vu4 (AUTHOR), Hinestrosa, Federico5 (AUTHOR), DeJesus, Edwin5 (AUTHOR)
Publikováno v:
Open Forum Infectious Diseases. 2019 Supplement, Vol. 6, pS861-S862. 2p.
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 224:117452
Nucleoside drugs are known for their remarkable anticancer and antiviral properties. The development of nucleoside drugs has attracted much attention and generated a great deal of research interest. β-L-cytidine and β-D-cytidine are a pair of cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4fd4ccbba45d1395936da887c4e966
https://doi.org/10.1016/j.saa.2019.117452
https://doi.org/10.1016/j.saa.2019.117452
Autor:
Maria Camila Castro, Vu Nguyen, Colton J Tucker, Edwin DeJesus, Federico Hinestrosa, Beth Bryant, Charlotte-Paige Rolle
Publikováno v:
Open Forum Infectious Diseases
Background Dual dolutegravir (DTG)-containing regimens (DCRs) are currently approved for the treatment of antiretroviral (ARV) naïve and experienced patients with HIV-1 infection. DTG monotherapy has resulted in unacceptable rates of virologic failu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63883460f85653e9a67a633b6d36c713
https://doi.org/10.1093/ofid/ofz360.2164
https://doi.org/10.1093/ofid/ofz360.2164