Zobrazeno 1 - 10
of 2 375
pro vyhledávání: '"Cytoprotective"'
Autor:
Meirui Qian, Ziyu Wan, Xue Liang, Lin Jing, Huijie Zhang, Heyao Qin, Wenli Duan, Ruo Chen, Tianjiao Zhang, Qian He, Meng Lu, Jianli Jiang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background/Aims Chemotherapy resistance in liver cancer is a major clinical issue, with CD147 playing a vital role in this process. However, the specific mechanisms underlying these processes remain largely unknown. This study investigates h
Externí odkaz:
https://doaj.org/article/bace4bb2e8e54abbbe828f38d3ab49bf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In response to the growing demand for high-value bioactive compounds, microalgae cultivation has gained a significant acceleration in recent years. Among these compounds, antioxidants have emerged as essential constituents in the food, pharm
Externí odkaz:
https://doaj.org/article/920da6ec2d50405485c9af8a2059aada
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 9215-9233 (2024)
The thymus, a central lymphoid organ in animals, serves as the site for T cell development, differentiation and maturation, vital to adaptive immunity. The thymus is critical for maintaining tissue homeostasis to protect against tumors and tissue dam
Externí odkaz:
https://doaj.org/article/0050ab48368b47eb8fff14ce6dfc3439
Autor:
E. B. Faizuloev, I. A. Leneva, V. S. Smirnov, D. I. Smirnova, A. V. Gracheva, E. R. Korchevaya, D. M. Khokhlova, T. A. Kudryavtseva, S. V. Petlenko, V. A. Zaplutanov
Publikováno v:
Антибиотики и Химиотерапия, Vol 69, Iss 3-4, Pp 31-41 (2024)
Introduction. Rotavirus infection causes more than 250 million episodes of acute gastroenteritis annually, of which approximately 130,000 cases in children under 5 years of age are fatal. In this regard, the search for drugs for the treatment of rota
Externí odkaz:
https://doaj.org/article/18a064049d314da29ab59c3eeffe872a
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34480- (2024)
Exposure to cadmium (Cd) results in bioaccumulation and irreversible damage; this encourages an investigation of alternatives to address Cd toxicity, using natural compounds. Lysiphyllum strychnifolium, a well-known Thai medicinal plant, was investig
Externí odkaz:
https://doaj.org/article/27f60de2b5a44a209d913747c575e1b2
Autor:
Pramote Mahakunakorn, Pimpichaya Sangchart, Panyada Panyatip, Juthamat Ratha, Teerasak Damrongrungruang, Aroonsri Priprem, Ploenthip Puthongking
Publikováno v:
PeerJ, Vol 12, p e17608 (2024)
According to our preliminary study, melatonin and its N-amide derivatives (N-(2-(1-4-bromobenzoyl-5-methoxy-1H-indol-3-yl)ethyl)acetamide (BBM) and 4-bromo-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)benzamide (EBM)) inhibited the marker of acute inflammatio
Externí odkaz:
https://doaj.org/article/fa7bb1abda6b47219e7d1cdbaee55cb4
Autor:
Sara Avilés-Gaxiola, Laura Aracely Contreras-Angulo, Israel García-Aguiar, J. Basilio Heredia
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1367 (2024)
Reactive oxygen species are produced as part of the cellular metabolism. However, lifestyle can promote an excess in their concentration. Free radicals react with DNA, promoting the appearance of cancer cells. Therefore, natural antioxidants have bee
Externí odkaz:
https://doaj.org/article/120cd86db74c4d62abe13f62ec0422af
Autor:
Chrisyella Cendara Purba, Yunika Mayangsari, Widiastuti Setyaningsih, Worrapanit Chansuwan, Nualpun Sirinupong
Publikováno v:
Future Foods, Vol 9, Iss , Pp 100350- (2024)
Citrus hystrix is a fruit native to tropical Southeast Asia and Southern China. The fruits and leaves are well-known spice ingredients in Asian dishes, but the peels are usually discarded, producing a large amount of waste despite the presence of phe
Externí odkaz:
https://doaj.org/article/21c5e086b62548189cb7cb49fea04eda
Autor:
Yuqin Peng, Qingfan Ren, Huanrong Ma, Chuman Lin, Mingjia Yu, Yongchuan Li, Jiancong Chen, Haihao Xu, Peng Zhao, Suyue Pan, Jia Tao, Kaibin Huang
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103106- (2024)
Cytoprotection has emerged as an effective therapeutic strategy for mitigating brain injury following acute ischemic stroke (AIS). The sulfonylurea receptor 1-transient receptor potential M4 (SUR1-TRPM4) channel plays a pivotal role in brain edema an
Externí odkaz:
https://doaj.org/article/e042d005ee6741e19a6f54a4146bc3ac
Publikováno v:
Autophagy Reports, Vol 2, Iss 1, Pp 1-16 (2023)
Topoisomerase I inhibitors represent a widely used class of antineoplastic agents that promote both single-stranded and double-stranded breaks in the DNA of tumor cells, leading to tumor cell death. Topotecan and irinotecan are the clinically relevan
Externí odkaz:
https://doaj.org/article/f71762f0db744e1ca5af4fc997ccbde9