Zobrazeno 1 - 10
of 425
pro vyhledávání: '"Cytoplasmic polyadenylation element"'
Autor:
Ran You, Yanjun Yang, Guowen Yin, Hao Jiang, Yousheng Lu, Liang Gui, Jun Bao, Qingyu Xu, Liang Feng
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1887 (2023)
Hepatocellular carcinoma (HCC) is a prevalent and high-mortality cancer worldwide, and its complexity necessitates novel strategies for drug selection and design. Current approaches primarily focus on reducing gene expression, while promoting gene ov
Externí odkaz:
https://doaj.org/article/4e1686df352d426d9a47aacdc4aac496
Autor:
Rubén Hervás, María del Carmen Fernández-Ramírez, Albert Galera-Prat, Mari Suzuki, Yoshitaka Nagai, Marta Bruix, Margarita Menéndez, Douglas V. Laurents, Mariano Carrión-Vázquez
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Amyloids are ordered, insoluble protein aggregates, characterized by a cross-β sheet quaternary structure in which molecules in a β-strand conformation are stacked along the filament axis via intermolecular interactions. While a
Externí odkaz:
https://doaj.org/article/424f921c44eb4d14bf0ae0e29dc08050
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Crosstalk between cancer cells and tumor-associated macrophages (TAMs) mediates tumor progression in colorectal cancer (CRC). Cytoplasmic polyadenylation element binding protein 3 (CPEB3) has been shown to exhibit tumor-suppressiv
Externí odkaz:
https://doaj.org/article/2c7184992421439890ffcf339ea72e05
Autor:
Yanlong Wang, Jiyu Yang, Pangtao Chen, Yu Song, Weizheng An, Haoran Zhang, Butegeleqi Butegeleqi, Jinglong Yan
Publikováno v:
Cancer Medicine, Vol 9, Iss 8, Pp 2833-2845 (2020)
Abstract Osteosarcoma is a primary malignant bone tumor, which affects children, adolescents, and young adults commonly. MicroRNAs (miRNAs) have been proved to be dysregulated in different cancers, including osteosarcoma. Although miR‐320a has been
Externí odkaz:
https://doaj.org/article/9f4831b298a444478a090e38b977f4e2
Akademický článek
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Akademický článek
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Autor:
Feng, Ran You, Yanjun Yang, Guowen Yin, Hao Jiang, Yousheng Lu, Liang Gui, Jun Bao, Qingyu Xu, Liang
Publikováno v:
Pharmaceutics; Volume 15; Issue 7; Pages: 1887
Hepatocellular carcinoma (HCC) is a prevalent and high-mortality cancer worldwide, and its complexity necessitates novel strategies for drug selection and design. Current approaches primarily focus on reducing gene expression, while promoting gene ov
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 21 No. 6 (2022); 1147-1152
Purpose: To investigate the differential expression of BCL9 in cervical carcinoma samples, analyze its biological functions in regulating malignant phenotypes of cervical carcinoma cells, and to explore its potential molecular mechanism.Methods: Expr
Publikováno v:
Neurosci Res
A dataset of single-nucleus RNA sequencing (snRNAseq) data was analyzed using Seurat, Sierra, and Ingenuity Pathway Analysis (IPA) programs to assess differentially expressed genes (DEGs) and differential transcript usage (DTU) in mouse hippocampal c
Autor:
Sumika Sakamoto, Yasuko Noda, Shinichi Hayashi, Yukie Hirahara, Taro Koike, Susumu Tanaka, Rio Kakizaki, Hisao Yamada, Souichi Oe, Masaaki Kitada
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 82-94 (2022)
FEBS Open Bio
FEBS Open Bio
Cytoplasmic polyadenylation element binding protein 1 (CPEB1) regulates the translation of numerous mRNAs. We previously showed that AU‐rich binding factor 1 (AUF1) regulates Cpeb1 expression through the 3’ untranslated region (3’UTR). To inves