Zobrazeno 1 - 10
of 1 317
pro vyhledávání: '"Cytoplasmic polyadenylation"'
Publikováno v:
Regenerative Therapy, Vol 20, Iss , Pp 107-116 (2022)
Objective: Bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) could mediate the malignancy of tumor cells by transmitting targeted cargo. Therein, this study intends to explore the function of BMSC-Exos transmitting microRNA-425 (miR-425)
Externí odkaz:
https://doaj.org/article/f65f8881b0fd470195fcff5ddbbbae61
Autor:
Ran You, Yanjun Yang, Guowen Yin, Hao Jiang, Yousheng Lu, Liang Gui, Jun Bao, Qingyu Xu, Liang Feng
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1887 (2023)
Hepatocellular carcinoma (HCC) is a prevalent and high-mortality cancer worldwide, and its complexity necessitates novel strategies for drug selection and design. Current approaches primarily focus on reducing gene expression, while promoting gene ov
Externí odkaz:
https://doaj.org/article/4e1686df352d426d9a47aacdc4aac496
Autor:
Rubén Hervás, María del Carmen Fernández-Ramírez, Albert Galera-Prat, Mari Suzuki, Yoshitaka Nagai, Marta Bruix, Margarita Menéndez, Douglas V. Laurents, Mariano Carrión-Vázquez
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Amyloids are ordered, insoluble protein aggregates, characterized by a cross-β sheet quaternary structure in which molecules in a β-strand conformation are stacked along the filament axis via intermolecular interactions. While a
Externí odkaz:
https://doaj.org/article/424f921c44eb4d14bf0ae0e29dc08050
Autor:
Souichi Oe, Shinichi Hayashi, Susumu Tanaka, Taro Koike, Yukie Hirahara, Ryohei Seki-Omura, Rio Kakizaki, Sumika Sakamoto, Yosuke Nakano, Yasuko Noda, Hisao Yamada, Masaaki Kitada
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Fragile X syndrome (FXS) is an inherited intellectual disability caused by a deficiency in Fragile X mental retardation 1 (Fmr1) gene expression. Recent studies have proposed the importance of cytoplasmic polyadenylation element-binding protein 1 (CP
Externí odkaz:
https://doaj.org/article/cb5a6842b2af4a2798eaee3d8190d65a
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Crosstalk between cancer cells and tumor-associated macrophages (TAMs) mediates tumor progression in colorectal cancer (CRC). Cytoplasmic polyadenylation element binding protein 3 (CPEB3) has been shown to exhibit tumor-suppressiv
Externí odkaz:
https://doaj.org/article/2c7184992421439890ffcf339ea72e05
Autor:
Yanlong Wang, Jiyu Yang, Pangtao Chen, Yu Song, Weizheng An, Haoran Zhang, Butegeleqi Butegeleqi, Jinglong Yan
Publikováno v:
Cancer Medicine, Vol 9, Iss 8, Pp 2833-2845 (2020)
Abstract Osteosarcoma is a primary malignant bone tumor, which affects children, adolescents, and young adults commonly. MicroRNAs (miRNAs) have been proved to be dysregulated in different cancers, including osteosarcoma. Although miR‐320a has been
Externí odkaz:
https://doaj.org/article/9f4831b298a444478a090e38b977f4e2
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Akademický článek
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Autor:
Bettina Drisaldi, Luca Colnaghi, Amir Levine, YanYou Huang, Anna M. Snyder, Daniel J. Metzger, Martin Theis, Denise B. Kandel, Eric R. Kandel, Luana Fioriti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
A recurrent and devastating feature of addiction to a drug of abuse is its persistence, which is mediated by maladaptive long-term memories of the highly pleasurable experience initially associated with the consumption of the drug. We have recently f
Externí odkaz:
https://doaj.org/article/eecf03f4d98040a38043da74d23a3a4a