Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Cytoplasmic hybrid"'
Autor:
Mei Qing, Rong Wang, Xiuxin Deng, Wen-Wu Guo, Xiao-Meng Wu, Chao-Chao Li, Kai-Dong Xie, Yan-Ni Fang
Publikováno v:
Plant Physiology. 183:1681-1695
MicroRNA399 (miR399) regulates phosphate homeostasis in plants by down-regulating the expression of PHOSPHATE2 (PHO2, or UBC24 encoding the ubiquitin-conjugating E2 enzyme). We previously identified CsmiR399a.1 in a small RNA sequencing screen of a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2db9a05bc3612e243d7ac5e33a51f08a
https://doi.org/10.1104/pp.20.00129
https://doi.org/10.1104/pp.20.00129
Mitochondria are organelles that produce cellular energy in the form of ATP through oxidative phosphorylation, and this primary function is conserved between many taxa. Locomotion is a trait that is highly reliant on metabolic function and expected t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017dc5beffa8e2a4789d00eea0b17d45
https://doi.org/10.1101/2021.10.30.464953
https://doi.org/10.1101/2021.10.30.464953
Autor:
Marine Bouhier, Emmanuel Tetaud, Elodie Sardin, Déborah Tribouillard-Tanvier, Malgorzata Rak, Huimei Chen, Bénédicte Salin, Xin Su, Jean-Paul di Rago, François Godard, Kewin Gombeau, Derek Caetano-Anollés
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2019, 28 (22), pp.3792-3804. ⟨10.1093/hmg/ddz160⟩
Human Molecular Genetics, Oxford University Press (OUP), 2019, ⟨10.1093/hmg/ddz160⟩
Human Molecular Genetics, Oxford University Press (OUP), 2019, 28 (22), pp.3792-3804. ⟨10.1093/hmg/ddz160⟩
Human Molecular Genetics, Oxford University Press (OUP), 2019, ⟨10.1093/hmg/ddz160⟩
The m.8993T>G mutation of the mitochondrial MT-ATP6 gene has been associated with numerous cases of neuropathy, ataxia and retinitis pigmentosa and maternally inherited Leigh syndrome, which are diseases known to result from abnormalities affecting m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed524c64b6c39a053bab73cbfde17afc
https://doi.org/10.1093/hmg/ddz160
https://doi.org/10.1093/hmg/ddz160
Publikováno v:
J Alzheimers Dis
Background: Mitochondrial dysfunction, bioenergetic deficit, and extensive oxidative stress underlie neuronal perturbation during the early stage of Alzheimer’s disease (AD). Previously, we demonstrated that decreased PTEN-induced putative kinase 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2caf9bf85de94dd27ab0db8504ec976
https://pubmed.ncbi.nlm.nih.gov/33998543
https://pubmed.ncbi.nlm.nih.gov/33998543
Autor:
Rachael A Lawson, Adam S. Butterworth, Emanuele Di Angelantonio, Klaudia Walter, Joanna M M Howson, Lixin Li, Caroline H. Williams-Gray, Ekaterina Yonova-Doing, Zoe J. Golder, Marta Camacho, Aurora Gomez-Duran, Peter M. Rothwell, Kousik Kundu, Na Cai, Maik Pietzner, Nicholas J. Wareham, John Danesh, Annette I. Burgess, Willem H. Ouwehand, Oliver Stegle, Marc Jan Bonder, Claudia Calabrese, Claudia Langenberg, Nicole Soranzo, Nicholas A. Watkins, Patrick F. Chinnery, David J. Roberts, Isobel D. Stewart
Publikováno v:
Nat. Med. 27, 1564-1575 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
47 p.-11 fig.
Mitochondrial DNA (mtDNA) variants influence the risk of late-onset human diseases, but the reasons for this are poorly understood. Undertaking a hypothesis-free analysis of 5,689 blood-derived biomarkers with mtDNA variants in 16,
Mitochondrial DNA (mtDNA) variants influence the risk of late-onset human diseases, but the reasons for this are poorly understood. Undertaking a hypothesis-free analysis of 5,689 blood-derived biomarkers with mtDNA variants in 16,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbb642b213962af1110ef829139d354
https://pubmed.ncbi.nlm.nih.gov/34663981
https://pubmed.ncbi.nlm.nih.gov/34663981
Autor:
Chen-Jui Ho, Chung-Wen Kuo, Pei-Wen Wang, Jiin-Haur Chuang, Meng-Han Tsai, Tsu-Kung Lin, Chia-Wei Liou
Publikováno v:
Cells
Volume 9
Issue 8
Cells, Vol 9, Iss 1885, p 1885 (2020)
Volume 9
Issue 8
Cells, Vol 9, Iss 1885, p 1885 (2020)
Mitochondrial dysfunction is involved in the pathogenesis of atherosclerosis, the primary risk factor for ischemic stroke. This study aims to explore the role of mitochondrial genomic variations in ischemic stroke, and to uncover the nuclear genes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af50c24817caeedfac5535bd62540ccf
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics, Vol 11 (2020)
Mitochondrial DNA (mtDNA) haplogroups have been associated with functional impairments (i.e., decreased gait speed and grip strength, frailty), which are risk factors of disability. However, the association between mtDNA haplogroups and ADL disabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913f57f5e2864d151ed686f9b4307c0a
https://pubmed.ncbi.nlm.nih.gov/33193696
https://pubmed.ncbi.nlm.nih.gov/33193696
Autor:
Hezhi Fang, Jianxin Lyu, Xiaoting Lou, Xiujuan Wei, Huaibin Zhou, Jie Xie, Qiongya Zhao, Qinxia Han, Lijun Shen, Yanling Yang, Deyu Chen, Xueyun Li, Jingting Xiong
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 5, Pp n/a-n/a (2020)
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine
Background The m.14487T>C mutation is recognized as a diagnostic mutation of mitochondrial disease during the past 16 years, emerging evidence suggests that mutant loads of m.14487T>C and disease phenotype are not closely correlated. Methods Immortal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d5ccbe4b902318a1e627d2e16c490c
https://doaj.org/article/cdc985e62e854be8bd38ef4c18ddddcd
https://doaj.org/article/cdc985e62e854be8bd38ef4c18ddddcd
Autor:
Anuradha Kalani, Lewis Hutfles, Blaise W. Menta, Ian Weidling, Russell H. Swerdlow, Heather M. Wilkins, Benjamin J. Ryan, Judit Perez-Ortiz, Xiaowan Wang, T. Chris Gamblin, Scott J. Koppel
Publikováno v:
J Alzheimers Dis
Background: Mitochondrial dysfunction and tau aggregation occur in Alzheimer’s disease (AD), and exposing cells or rodents to mitochondrial toxins alters their tau. Objective: To further explore how mitochondria influence tau, we measured tau oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31f313af9a48d2607c56c4d0adaf2c0
https://europepmc.org/articles/PMC7962146/
https://europepmc.org/articles/PMC7962146/
Autor:
Haiying Li, Pingping Jiang, Ling Xue, Zhi Lin, Meng Wang, Mi Zhou, Xiaofen Jin, Min-Xin Guan, Wenwen Shi, Yaru Chen, Qiufen He
Publikováno v:
Journal of Biological Chemistry. 292:13934-13946
Several mitochondrial tRNA mutations have been associated with hypertension, but their pathophysiology remains poorly understood. In this report, we identified a novel homoplasmic 3253T→C mutation in the mitochondrial tRNALeu(UUR) gene in a Han Chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d815968e736d641d0c5b6c408972b26a
https://doi.org/10.1074/jbc.m117.787028
https://doi.org/10.1074/jbc.m117.787028