Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cytomegalovirus Infections/immunology"'
Autor:
Antoine Blancher, Sandrine Sourdet, Nicolas Congy-Jolivet, Kevin Guedj, Francis Roubinet, Bénédicte Puissant-Lubrano, Fati Nourhashemi, Sophie Guyonnet, Pol André Apoil
Publikováno v:
Immunology and Cell Biology
Immunology and Cell Biology, Nature Publishing Group, 2018, 96 (1), pp.114-120. ⟨10.1111/imcb.1004⟩
Immunology and Cell Biology, Nature Publishing Group, 2018, 96 (1), pp.114-120. ⟨10.1111/imcb.1004⟩
International audience; We analyzed the impact of age, sex, and CMV on blood monocyte and dendritic cell (DC) subpopulations in 256 healthy individuals aged from 19 to 96 years. Flow cytometry was performed on whole blood within the 4 h following blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae522a83d91a18d53b482b59de11cf8
https://doi.org/10.1111/imcb.1004
https://doi.org/10.1111/imcb.1004
Autor:
Stempel, Markus, Chan, Baca, Juranić Lisnić, Vanda, Krmpotić, Astrid, Hartung, Josephine, Paludan, Søren R., Füllbrunn, Nadia, Lemmermann, Niels A.W., Brinkmann, Melanie M.
Publikováno v:
The EMBO journal
Stempel, M, Chan, B, Juranić Lisnić, V, Krmpotić, A, Hartung, J, Paludan, S R, Füllbrunn, N, Lemmermann, N A W & Brinkmann, M M 2019, ' The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection ', EMBO Journal, vol. 38, no. 5, e100983 . https://doi.org/10.15252/embj.2018100983
Stempel, M, Chan, B, Juranić Lisnić, V, Krmpotić, A, Hartung, J, Paludan, S R, Füllbrunn, N, Lemmermann, N A W & Brinkmann, M M 2019, ' The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection ', EMBO Journal, vol. 38, no. 5, e100983 . https://doi.org/10.15252/embj.2018100983
Cytomegaloviruses (CMVs) are master manipulators of the host immune response. Here, we reveal that the murine CMV (MCMV) protein m152 specifically targets the type I interferon (IFN) response by binding to stimulator of interferon genes (STING), ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7fa460c44afcc5493733338e6428a20c
https://hdl.handle.net/10033/621687
https://hdl.handle.net/10033/621687
Publikováno v:
Experimental Gerontology. 77:87-95
INTRODUCTION: Immunosenescence is the age-related deterioration of immunocompetence which is reflected in a poorer response to new antigens. This process is characterized by decreases in naïve T cells and increases in memory T cells. The highly prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::c0d10d6d115c084d09f9f27a3ad000f7
https://research.rug.nl/en/publications/864557da-cde6-4076-9ebd-349d4224dcf8
https://research.rug.nl/en/publications/864557da-cde6-4076-9ebd-349d4224dcf8
Publikováno v:
Experimental Gerontology. 77:87-95
Introduction Immunosenescence is the age-related deterioration of immunocompetence which is reflected in a poorer response to new antigens. This process is characterized by decreases in naive T cells and increases in memory T cells. The highly preval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32af887dae2f324adc4c1cf988ae9cee
https://doi.org/10.1016/j.exger.2016.02.005
https://doi.org/10.1016/j.exger.2016.02.005
Autor:
Evelyna Derhovanessian, Karin Hähnel, Andrea B. Maier, Graham Pawelec, Helene Roelofs, Anton J. M. de Craen, Rudi G. J. Westendorp, Sai-Juan Chen
Publikováno v:
The journals of gerontology. Series A : Biological sciences and medical sciences, 70(8), 917-23. Oxford University Press
Journal of Gerontology: Medical Sciences, 70(8), 917-923
Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 70(8), 917-923. Oxford University Press
Derhovanessian, E, Chen, S, Maier, A B, Hähnel, K, de Craen, A J M, Roelofs, H, Westendorp, R & Pawelec, G 2015, ' CCR4+ Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival ', The journals of gerontology. Series A : Biological sciences and medical sciences, vol. 70, no. 8, pp. 917-23 . https://doi.org/10.1093/gerona/glu128
Derhovanessian, E, Chen, S, Maier, A B, Hahnel, K, Craen, A J M, Roelofs, H, Westendorp, R & Pawelec, G 2015, ' CCR4(+) Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival ', Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, vol. 70, no. 8, pp. 917-923 . https://doi.org/10.1093/gerona/glu128
Journal of Gerontology: Medical Sciences, 70(8), 917-923
Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 70(8), 917-923. Oxford University Press
Derhovanessian, E, Chen, S, Maier, A B, Hähnel, K, de Craen, A J M, Roelofs, H, Westendorp, R & Pawelec, G 2015, ' CCR4+ Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival ', The journals of gerontology. Series A : Biological sciences and medical sciences, vol. 70, no. 8, pp. 917-23 . https://doi.org/10.1093/gerona/glu128
Derhovanessian, E, Chen, S, Maier, A B, Hahnel, K, Craen, A J M, Roelofs, H, Westendorp, R & Pawelec, G 2015, ' CCR4(+) Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival ', Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, vol. 70, no. 8, pp. 917-923 . https://doi.org/10.1093/gerona/glu128
CD4(+) regulatory T cells (Tregs) are a distinct population of T cells involved in maintaining peripheral tolerance to self-antigens. Several studies have shown increased frequency and number of Tregs in the elderly. Whether such an increase has any
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab35a55b73660e461c194fb87383a702
https://doi.org/10.1093/gerona/glu128
https://doi.org/10.1093/gerona/glu128
Publikováno v:
Christensen-Quick, Aaron; Vanpouille, Christophe; Lisco, Andrea; & Gianella, Sara. (2017). Cytomegalovirus and HIV Persistence: Pouring Gas on the Fire. AIDS Research and Human Retroviruses, 33(S1), S23-s30. doi: 10.1089/aid.2017.0145. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/9vn4h9q2
AIDS research and human retroviruses, vol 33, iss S1
AIDS research and human retroviruses, vol 33, iss S1
The inherent stability of a small population of T cells that are latently infected with HIV despite antiretroviral therapy (ART) remains a stubborn obstacle to an HIV cure. By exploiting the memory compartment of our immune system, HIV maintains pers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2555f8c2584b528b56baa106610ca51
https://europepmc.org/articles/PMC5684659/
https://europepmc.org/articles/PMC5684659/
Autor:
Michael P. Dubé, Richard Haubrich, Erick T. Tatro, Sheldon R. Morris, Douglas D. Richman, Davey M. Smith, Sara Gianella, Eric S. Daar, Susan J. Little, M. Vargas
Publikováno v:
Gianella, Sara; Morris, Sheldon R; Tatro, Erick; Vargas, Milenka V; Haubrich, Richard H; Daar, Eric S; et al.(2014). Virologic correlates of anti-CMV IgG levels in HIV-1-infected men.. The Journal of infectious diseases, 209(3), 452-456. doi: 10.1093/infdis/jit434. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/50d847rr
The Journal of infectious diseases, vol 209, iss 3
The Journal of infectious diseases, vol 209, iss 3
In human immunodeficiency virus (HIV)-infected individuals, higher levels of anti-cytomegalovirus (CMV) immunoglobulin G (IgG) antibody have been associated with increased immune activation, increased HIV transmission, cardiovascular complications, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702c55d6a6cc0ada971c65fd98b0c9b7
http://www.escholarship.org/uc/item/50d847rr
http://www.escholarship.org/uc/item/50d847rr
Autor:
Tomić, Adriana, Varanasi, Pavankumar R., Golemac, Mijo, Malić, Suzana, Riese, Peggy, Mischak-Weissinger, Eva, Guzman, CA, Krmpotić, Astrid, Jonjić, Stipan, Messerle, Martin
Publikováno v:
PLoS Pathogens
Volume 12
Issue 12
ournals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006015
Volume 12
Issue 12
ournals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006015
Development of an effective vaccine against human cytomegalovirus (HCMV) is a need of utmost medical importance. Generally, it is believed that a live attenuated vaccine would best provide protective immunity against this tenacious pathogen. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a767dbb83e559997bff0d60b01e26adc
https://repository.medri.uniri.hr/islandora/object/medri:1382
https://repository.medri.uniri.hr/islandora/object/medri:1382
Autor:
Daniel E. Speiser, Leticia Barba, Amandine Legat, Lukas Baitsch, Nathalie Rufer, Hanifa Bouzourene, Sunil K. Raghav, Petra Baumgaertner, Pedro Romero, Bart Deplancke, Sébastien Wieckowski, Estelle Devevre
Publikováno v:
Journal of Clinical Investigation, vol. 121, no. 6, pp. 2350-2360
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (6), pp.2350-2360. ⟨10.1172/JCI46102⟩
The Journal of clinical investigation
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (6), pp.2350-2360. ⟨10.1172/JCI46102⟩
The Journal of clinical investigation
International audience; In chronic viral infections, CD8⁺ T cells become functionally deficient and display multiple molecular alterations. In contrast, only little is known of self- and tumor-specific CD8⁺ T cells from mice and humans. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fae003bc650a938f54e2ed5ba1e640
https://doi.org/10.1172/jci46102
https://doi.org/10.1172/jci46102
Autor:
Tessa Braeckman, Kirsten Van Camp, Pierre Van Damme, Barbara Stein, Amaryllis H. Van Craenenbroeck, Griet Nijs, Nathalie Cools, Zwi N. Berneman, Gert A. Verpooten, Ann Van de Velde, Sébastien Anguille, Evelien Smits, Herman Goossens, Viggo Van Tendeloo, Margareta Ieven
Publikováno v:
Transplantation
Background Infection with human cytomegalovirus (CMV) is a significant cause of morbidity and mortality in solid organ and hematopoietic stem cell transplant (HSCT) recipients. Methods The present study explored the safety, feasibility, and immunogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fc2bdd54f48c5a40dbd0a34a9d46d3
https://biblio.vub.ac.be/vubir/induction-of-cytomegalovirusspecific-t-cell-responses-in-healthy-volunteers-and-allogeneic-stem-cell-recipients-using-vaccination-with-messenger-rnatransfected-dendritic-cells(21b38f07-f12b-419b-ab2d-5ee5b50e862e).html
https://biblio.vub.ac.be/vubir/induction-of-cytomegalovirusspecific-t-cell-responses-in-healthy-volunteers-and-allogeneic-stem-cell-recipients-using-vaccination-with-messenger-rnatransfected-dendritic-cells(21b38f07-f12b-419b-ab2d-5ee5b50e862e).html