Effects of indirubin and isatin on cell viability, mutagenicity, genotoxicity and BAX/ERCC1 gene expression

Autor: Manoela Viar Fogaça, Priscila de Matos Cândido-Bacani, Lucas Milanez Benicio, Lara Martinelli Zapata, Priscilla de Freitas Cardoso, Marcelo Tempesta de Oliveira, Tamara Regina Calvo, Eliana Aparecida Varanda, Wagner Vilegas, Ilce Mara de Syllos Cólus

Publikováno v: Pharmaceutical Biology, Vol 55, Iss 1, Pp 2005-2014 (2017)

Context: Indigofera suffruticosa Miller (Fabaceae) and I. truxillensis Kunth produce compounds, such as isatin (ISA) and indirubin (IRN), which possess antitumour properties. Their effects in mammalian cells are still not very well understood. Object

Externí odkaz: https://doaj.org/article/61056a3a62eb4099a13754b8c083efe3

Application of the micronucleus assay performed by different scorers in case of large-scale radiation accidents

Autor: Rawojć Kamila, Tarnawska Dorota M., Miszczyk Justyna U., Swakoń Jan, Stolarczyk Liliana, Rydygier Marzena

Publikováno v: Nukleonika, Vol 60, Iss 3, Pp 643-649 (2015)

Mass casualty scenarios of radiation exposure require high throughput biological dosimetry techniques for population triage, in order to rapidly identify individuals, who require clinical treatment. Accurate dose estimates can be made by biological d

Externí odkaz: https://doaj.org/article/38e57be803654828995ead40394f5c07

Assessment of Cytogenetic Damage and Cholinesterases’ Activity in Workers Occupationally Exposed to Pesticides in Zamora-Jacona, Michoacan, Mexico

Autor: Rafael Valencia-Quintana, Mirta Milić, M. Urióstegui-Acosta, Rosa María López-Durán, José Luis Gómez-Olivares, Juana Sánchez-Alarcón, Ma Antonieta Ochoa-Ocaña, Guillermo Alejandro Pérez-Flores, Stefano Bonassi

Publikováno v: International Journal of Environmental Research and Public Health, Vol 18, Iss 6269, p 6269 (2021)
International Journal of Environmental Research and Public Health
Volume 18
Issue 12

Pesticides have been considered as potential chemical mutagens
however, little is known about toxic and genotoxic effects during pesticide application in Zamora-Jacona, Michoacan State in Mexico. This study sought to determine DNA damage and cho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d886c6aa0642d68eb040c96481fe505
https://www.mdpi.com/1660-4601/18/12/6269

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Application of the micronucleus assay performed by different scorers in case of large-scale radiation accidents

Autor: Jan Swakoń, Dorota M. Tarnawska, Justyna Miszczyk, K. Rawojć, Liliana Stolarczyk, Marzena Rydygier

Publikováno v: Nukleonika, Vol 60, Iss 3, Pp 643-649 (2015)

Mass casualty scenarios of radiation exposure require high throughput biological dosimetry techniques for population triage, in order to rapidly identify individuals, who require clinical treatment. Accurate dose estimates can be made by biological d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d087de975de394359c4e6b973778ed
https://doaj.org/article/38e57be803654828995ead40394f5c07