Zobrazeno 1 - 10
of 10 252
pro vyhledávání: '"Cytokine secretion"'
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Human papillomavirus (HPV) 11/16 E6/E7 proteins have been recognized to be pivotal in viral pathogenesis. This study sought to uncover the potential mechanisms of how HPV11/16 E6/E7-transfected keratinocytes inhibit cytokine secretion in per
Externí odkaz:
https://doaj.org/article/19dbee687ccb4686ba5c9ec2725e88e9
Autor:
Julia Jolibois, Alison Domingues, Divina El Hamaoui, Raphaël Awaida, Mathilde Berger-de-Gaillardo, Daniel Guérin, David M Smadja, Perrine Marquet-DeRougé, Isabelle Margaill, Elisa Rossi, Valérie Nivet-Antoine
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background This study explores the potential role of Thioredoxin-interacting protein (TXNIP) silencing in endothelial colony-forming cells (ECFCs) within the scope of age-related comorbidities and impaired vascular repair. We aim to elucidat
Externí odkaz:
https://doaj.org/article/23f9a1a27f634f52abc59e9518de0b30
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 3173-3185 (2024)
Wenbin Li,1,2,* Haohan Zhang,3,* Zuo You,4 Baozhu Guo5 1Department of Clinical Oncology, Qianjiang Hospital Affiliated to Renmin Hospital of Wuhan University, Qianjiang, Hubei, People’s Republic of China; 2Department of Clinical Oncology, Q
Externí odkaz:
https://doaj.org/article/1086b8ff6ae04cb0bd51b38a28e49e47
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHuman peripheral blood mononuclear cells (hPBMCs) are widely used in fundamental research and clinical applications as studying their responses to in vitro activation is an effective way to uncover functional alterations and disease assoc
Externí odkaz:
https://doaj.org/article/d952adcff0a74943aa1d9ffd17680477
Publikováno v:
eLife, Vol 12 (2024)
Cytokine polyfunctionality is a well-established concept in immune cells, especially T cells, and their ability to concurrently produce multiple cytokines has been associated with better immunological disease control and subsequent effectiveness duri
Externí odkaz:
https://doaj.org/article/abaf4b1673fd4ced98865c12f61c7736
Autor:
Putri Mandasari, Claudia Hollmann, Rehan-Haider Zaidi, Samira Löw, Jann Schrama, Dominik Wigger, Fabian Schumacher, Burkhard Kleuser, Niklas Beyersdorf
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acid ceramidase (Ac) is a lysosomal enzyme catalyzing the generation of sphingosine from ceramide, and Ac inhibitors are currently being investigated as potential cancer therapeutics. Yet, the role of the Ac in immune responses, particularly anti-vir
Externí odkaz:
https://doaj.org/article/37b2a7f242774e8abceb030bf1d4fd91
Functional and Multi-Omics Effects of an Optimized CRISPR-Mediated FURIN Depletion in U937 Monocytes
Publikováno v:
Cells, Vol 13, Iss 7, p 588 (2024)
The pro-protein convertase FURIN (PCSK3) is implicated in a wide range of normal and pathological biological processes such as infectious diseases, cancer and cardiovascular diseases. Previously, we performed a systemic inhibition of FURIN in a mouse
Externí odkaz:
https://doaj.org/article/de9bf4418c2e4b10921cfa1c2b0c5e82
Publikováno v:
Microorganisms, Vol 11, Iss 12, p 2942 (2023)
This study delves into the temporal dynamics of bacterial interactions in the gastrointestinal tract, focusing on how probiotic strains and pathogenic bacteria influence each other and human health. This research explores adhesion, competitive exclus
Externí odkaz:
https://doaj.org/article/c2e1216d18e14918b1628b362c84087d
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