Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cytokine redundancy"'
Autor:
Renate Burger, Matthias Peipp, Martin Gramatzki, John Wijdenes, Katja Klausz, Matthias Staudinger, Andreas Günther, Stefan Rose-John, Eva Maria Murga Penas
Publikováno v:
Haematologica. 102:381-390
Interleukin-6 has an important role in the pathophysiology of multiple myeloma where it supports the growth and survival of the malignant plasma cells in the bone marrow. It belongs to a family of cytokines which use the glycoprotein 130 chain for si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7be47d76e26617af630af22d7ba1e0
https://doi.org/10.3324/haematol.2016.145060
https://doi.org/10.3324/haematol.2016.145060
Autor:
Frances A. Lemckert, Jonathon D. Sedgwick, D. Sean Riminton, John D. Pollard, Deborah H. Strickland, Heinrich Körner
Publikováno v:
The Journal of Experimental Medicine
Lymphotoxin (LT) is widely regarded as a proinflammatory cytokine with activities equivalent to tumor necrosis factor (TNF). The contribution of LT to experimental autoimmune encephalomyelitis (EAE) was examined using TNF/LTα−/− mice, TNF−/−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dbfadf5a9866036be092f17184f2b8
http://europepmc.org/articles/PMC2212266
http://europepmc.org/articles/PMC2212266
Autor:
Li Zhou, Michael Friedmann, Eda T. Bloom, Warren J. Leonard, Jian-Xin Lin, James A. Weatherbee, Akira Yamauchi, Thi-Sau Migone, Monica Tseng, Judy A. Mietz, Susan D. John
Publikováno v:
Immunity. 2(4):331-339
To understand the molecular bases for cytokine redundancy and plelotropy, we have compared the Stat proteins activated in peripheral blood lymphocytes (PBLs) by cytokines with shared and distinct actions. Interleukin-2 (IL-2) rapidly activated Stat5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c34b8a3d642e984ba97a47d0749dec1
Autor:
Warren J. Leonard, Jian-Xin Lin
Publikováno v:
The Journal of allergy and clinical immunology. 105(5)
Cytokines represent a diverse group of molecules that transmit intercellular signals. These signals may either be autocrine (where the same cell both produces the cytokine and responds to it) or paracrine (where the cytokine is made by one cell and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e85f4744616d2f347fca98b526443c
https://pubmed.ncbi.nlm.nih.gov/10808165
https://pubmed.ncbi.nlm.nih.gov/10808165
Autor:
Anne Kelso
Publikováno v:
Immunology and cell biology. 72(1)
The redundancy of many cytokine functions that was first noted in vitro has now been confirmed in vivo with the demonstration that some of these functions can occur in mice rendered deficient in a cytokine or cytokine receptor by gene inactivation. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb276b529390b3bd7d4b937da811db7
https://pubmed.ncbi.nlm.nih.gov/8157291
https://pubmed.ncbi.nlm.nih.gov/8157291
Autor:
J T Whicher, S W Evans
Publikováno v:
Advances in Clinical Chemistry Volume 30 ISBN: 9780120103300
Publisher Summary This chapter discusses the physiological and pathophysiological aspects of cytokines. Despite the fact that many of the molecules are described on the basis of a single biological function, several molecules subsequently turned out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3bb89a63aeefe4288a3087f86ac864
https://doi.org/10.1016/s0065-2423(08)60194-8
https://doi.org/10.1016/s0065-2423(08)60194-8
