Zobrazeno 1 - 10
of 1 092
pro vyhledávání: '"Cytochrome P450 enzymes"'
Autor:
Yang Zhang, Xianrun Pan, Tianyu Shi, Zhifeng Gu, Zhaochang Yang, Minghao Liu, Yi Xu, Yu Yang, Liping Ren, Xiaoming Song, Hao Lin, Kejun Deng
Publikováno v:
Journal of Advanced Research, Vol 63, Iss , Pp 35-42 (2024)
Introduction: Cytochrome P450 enzymes (P450s) are recognized as the most versatile catalysts worldwide, playing vital roles in numerous biological metabolism and biosynthesis processes across all kingdoms of life. Despite the vast number of P450 gene
Externí odkaz:
https://doaj.org/article/40ec74566e684926b003352de594d87a
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 1-20 (2024)
Externí odkaz:
https://doaj.org/article/256c91312718416188fb414b89e6df2e
Publikováno v:
Engineering Microbiology, Vol 4, Iss 4, Pp 100166- (2024)
Cytochrome P450 enzymes (CYPs or P450s) and ferredoxins (Fdxs) are ubiquitously distributed in all domains of life. Bacterial P450s are capable of catalyzing various oxidative reactions with two electrons usually donated by Fdxs. Particularly in Stre
Externí odkaz:
https://doaj.org/article/e09da32c648f41f2be003c7ddcbcb874
Autor:
Gajanan R. Jadhav, Pius S. Fasinu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The recent re-emergence and the increasing popularity of nitazenes, a group of new synthetic opioids (NSO) that belong to the benzimidazole chemical class, has raised public health concerns. As a class of potential opioid analgesic agents whose devel
Externí odkaz:
https://doaj.org/article/74232b1e8769465483bb84697e1c0bba
Autor:
Lorenzo Pedroni, Daniel Zocchi Doherty, Chiara Dall’Asta, Gianni Galaverna, Stephen G. Bell, Luca Dellafiora
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 273, Iss , Pp 116167- (2024)
Mycotoxins are known environmental pollutants that may contaminate food and feed chains. Some mycotoxins are regulated in many countries to limit the trading of contaminated and harmful commodities. However, the so-called emerging mycotoxins are poor
Externí odkaz:
https://doaj.org/article/0005564a0c604e4299b51439c97df6b5
Autor:
Li Ma, Tianjian Sun, Yunjie Liu, Yue Zhao, Xiaohui Liu, Yuxuan Li, Xinwei Chen, Lin Cao, Qianqian Kang, Jiawei Guo, Lei Du, Wei Wang, Shengying Li
Publikováno v:
Synthetic and Systems Biotechnology, Vol 8, Iss 3, Pp 452-461 (2023)
Indigoids, a class of bis-indoles, have long been applied in dyeing, food, and pharmaceutical industries. Recently, interest in these ‘old’ molecules has been renewed in the field of organic semiconductors as functional building blocks for organi
Externí odkaz:
https://doaj.org/article/6e1a5288ce6a4117a53aee393ffc910e
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8567 (2024)
During gliotoxin biosynthesis in fungi, the cytochrome P450 GliF enzyme catalyzes an unusual C–N ring-closure step while also an aromatic ring is hydroxylated in the same reaction cycle, which may have relevance to drug synthesis reactions in biote
Externí odkaz:
https://doaj.org/article/56721565c8ee4b70a577335f487a94e5
Autor:
Katreece Feiertag, Mawien Karaca, Benjamin Fischer, Tanja Heise, Denise Bloch, Tobias Opialla, Tewes Tralau, Carsten Kneuer, Philip Marx-Stoelting
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 221-236 (2023)
Plant protection products (PPPs) consist of one or more active substances and several co-formulants. Active substances provide the functionality of the PPP and are consequently evaluated according to standard test methods set by legal data requiremen
Externí odkaz:
https://doaj.org/article/271014a9928b4282a71768cfeea04829
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 1032-1037 (2022)
Context Alpinetin, the major active constitutes of Alpinia katsumata Hayata (Zingiberaceae), has been demonstrated to possess the activity of anti-breast cancer. Cytochrome P450 enzymes (CYP450s) plays vital roles in the biotransformation of various
Externí odkaz:
https://doaj.org/article/e00c131d041a4cb5a370fa4810aaa58a
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundPharmacogenetic analyses can predict interpersonal differences in response to psychopharmacotherapy, which greatly facilitates the selection of the most effective medication at optimal doses. By personalizing therapy in this way, we can min
Externí odkaz:
https://doaj.org/article/f4857c9e31c7497ab8b9806b1019a058