Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Cytochrome P-450 CYP2C8 Inhibitors"'
Autor:
Templeton IE; Certara, UK Ltd. (Simcyp Division), Sheffield, UK., Rowland-Yeo K; Certara, UK Ltd. (Simcyp Division), Sheffield, UK., Jones HM; Certara, UK Ltd. (Simcyp Division), Sheffield, UK., Endres CJ; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA., Topletz-Erickson AR; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA., Sun H; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA., Lee AJ; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA.
Publikováno v:
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Feb; Vol. 115 (2), pp. 299-308. Date of Electronic Publication: 2023 Dec 08.
Autor:
Iga K; Pharmaceutical Research and Technology Unit, R & D Division, Pre-formulation Department, Towa Pharmaceutical Co., Ltd, Kyoto Research Park KISTIC #202, 134, Chudoji Minami-machi, Shimogyo-ku, Kyoto, 600-8813, Japan. kiga2020@outlook.jp., Kiriyama A; Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kodo Kyotanabe-shi, Kyoto, 610-0395, Japan.
Publikováno v:
Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Jan; Vol. 63 (1), pp. 43-56. Date of Electronic Publication: 2023 Nov 03.
Autor:
Chen J; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Wu J; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Guo N; CSPC Zhongqi Pharmaceutical Technology (SJZ) Co., Ltd., Shijiazhuang, Hebei Province, China., Song Y; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Li L; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Wang B; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Li J; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Hou M; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Yin H; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Zhang M; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Kong Y; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Wu X; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Li R; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Wu L; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Gao Q; Beijing Friendship Hospital, Capital Medical University, Beijing, China., Dong R; Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Publikováno v:
Clinical and translational science [Clin Transl Sci] 2024 Nov; Vol. 17 (11), pp. e70063.
Autor:
Bi YA; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., Jordan S; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., King-Ahmad A; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., West MA; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., Varma MVS; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA.
Publikováno v:
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Jun; Vol. 115 (6), pp. 1336-1345. Date of Electronic Publication: 2024 Feb 26.
Autor:
Di Paolo V; Laboratory of Drug Metabolism, Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. Electronic address: veronica.dipaolo@unipd.it., Ferrari FM; Department R&D, MeteRSit, Padova, Italy., Veronese D; Laboratory of Drug Metabolism, Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Poggesi I; Clinical Pharmacology, Modeling and Simulation, GlaxoSmithKline S.p.A., Verona, Italy., Quintieri L; Laboratory of Drug Metabolism, Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. Electronic address: luigi.quintieri@unipd.it.
Publikováno v:
Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 May-Jun; Vol. 127, pp. 107516. Date of Electronic Publication: 2024 May 20.
Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity.
Autor:
Qiu H; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Ali Z; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Bowlan J; Repare Therapeutics, 1 Broadway, 15th Floor, Cambridge, MA, 02142, USA., Caldwell R; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Gardberg A; Constellation Pharmaceuticals, 215 First Street, Suite 200, Cambridge, MA, 02142, USA., Glaser N; Merck KGaA, Frankfurter Str. 250, Darmstadt, 64293, Germany., Goutopoulos A; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Head J; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Johnson T; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Maurer C; Merck KGaA, Frankfurter Str. 250, Darmstadt, 64293, Germany., Georgi K; Merck KGaA, Frankfurter Str. 250, Darmstadt, 64293, Germany., Grenningloh R; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Fang Z; Merck KGaA, Frankfurter Str. 250, Darmstadt, 64293, Germany., Morandi F; Cellular Enzymology, F. Hoffmann-La Roche AG, Konzern-Hauptsitz, Grenzacherstrasse 124, 4070, Basel, Switzerland., Rohdich F; Merck KGaA, Frankfurter Str. 250, Darmstadt, 64293, Germany., Schmidt R; Merck KGaA, Frankfurter Str. 250, Darmstadt, 64293, Germany., Follis AV; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA., Sherer B; EMD Serono Research & Development Institute, 45 A Middlesex Turnpike, Billerica, MA, 01821, USA.
Publikováno v:
ChemMedChem [ChemMedChem] 2021 Dec 14; Vol. 16 (24), pp. 3653-3662. Date of Electronic Publication: 2021 Oct 08.
Autor:
Di Paolo V; Laboratory of Drug Metabolism, Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Ferrari FM; Department R&D, Polidoro S.p.A, Schio, Italy., Poggesi I; Department Clinical Pharmacology and Pharmacometrics, Janssen-Cilag S.p.A, Cologno Monzese, Italy., Quintieri L; Laboratory of Drug Metabolism, Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Publikováno v:
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Nov; Vol. 17 (11), pp. 1345-1352. Date of Electronic Publication: 2021 Nov 02.
Autor:
Kawahara B; Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California 95064, United States., Faull KF; Pasarow Mass Spectrometry Laboratory, Jane and Terry Semel Institute for Neuroscience and Human Behavior and Department of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California 90024, United States., Janzen C; Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California 90095, United States., Mascharak PK; Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California 95064, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 Jun 24; Vol. 64 (12), pp. 8437-8446. Date of Electronic Publication: 2021 Jun 07.
Autor:
Takita H; Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Laboratory for Safety Assessment and ADME, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, Shizuoka, Japan., Scotcher D; Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Chinnadurai R; Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Kalra PA; Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Galetin A; Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Publikováno v:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2020 Dec; Vol. 9 (12), pp. 695-706. Date of Electronic Publication: 2020 Nov 23.
Autor:
Kito T; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan., Ito S; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan., Mizuno T; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan., Maeda K; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan., Kusuhara H; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan. Electronic address: kusuhara@mol.f.u-tokyo.ac.jp.
Publikováno v:
Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2019 Feb; Vol. 34 (1), pp. 87-94. Date of Electronic Publication: 2018 Sep 20.