Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Cytidylyltransferase activity"'
Publikováno v:
Journal of Computer-Aided Molecular Design. 33:419-436
Malaria is a life-threatening mosquito-borne blood disease caused by infection with Plasmodium parasites. Anti-malarial drug resistance is a global threat to control and eliminate malaria and therefore, it is very important to discover and evaluate n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe8a1717f251ef9302a453b298485e3
https://doi.org/10.1007/s10822-019-00191-2
https://doi.org/10.1007/s10822-019-00191-2
Autor:
Marijana Petković, Jürgen Schiller, Snežana Pejić, Dunja Drakulić, Aleksandra Stefanović, Jadranka Miletić Vukajlović, Tihomir V. Ilić
Publikováno v:
Rapid Communications in Mass Spectrometry
Rationale: Changes in lipid composition might be associated with the onset and progression of various neurodegenerative diseases. Herein, we investigated the changes in the plasma phosphatidylcholine (PC)/lysophosphatidylcholine (LPC) ratios in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffd07f1425ccfff4919bb7460dbe4d7
https://vinar.vin.bg.ac.rs/handle/123456789/8476
https://vinar.vin.bg.ac.rs/handle/123456789/8476
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 36:153-161
We reported in a recent publication that hexadecylphosphocholine (HePC), a lysophospholipid analogue, reduces cell proliferation in HepG2 cells and at the same time inhibits the biosynthesis of phosphatidylcholine (PC) via CDP-choline by acting upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb26347b840b1249f7c94c3d0de908bb
https://doi.org/10.1016/s1357-2725(03)00193-6
https://doi.org/10.1016/s1357-2725(03)00193-6
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1044:70-76
Fetal lung fatty-acid synthase and choline-phosphate cytidylyltransferase activities are increased by glucocorticoids. There is evidence that the hormone increases synthesis of fatty-acid synthase but only increases the catalytic activity of the cyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ad5d85c5721c928ccd6ff7dc2ebdb2
https://doi.org/10.1016/0005-2760(90)90220-r
https://doi.org/10.1016/0005-2760(90)90220-r
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 4, Pp 711-722 (1997)
Scopus-Elsevier
Scopus-Elsevier
Phosphatidylcholine (PtdCho) biosynthesis was examined in the sterol regulatory defective (SRD) Chinese hamster ovary (CHO) cell line SRD 6. SRD 6 cells do not display transcriptional activation of sterol-regulated genes and are cholesterol auxotroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ceca11d3088d0910380a1daa3ea031
http://www.sciencedirect.com/science/article/pii/S0022227520372382
http://www.sciencedirect.com/science/article/pii/S0022227520372382
Publikováno v:
Leukemia Research. 20:947-951
Analogs of ether phospholipids have been shown to have selective anti-neoplastic activity. The compounds are known to inhibit phospholipid biosynthesis. This paper examines the effect of the alkyl-lysophospholipid, edelfosine, on the rate-limiting en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3dce94d19a9c4b4d350d756741713d7
https://doi.org/10.1016/s0145-2126(96)00070-7
https://doi.org/10.1016/s0145-2126(96)00070-7
Publikováno v:
Plant Molecular Biology. 31:205-211
CTP:phosphocholine cytidylyltransferase is a rate-limiting enzyme in biosynthesis of phosphatidylcholine in plant cells. We have isolated four cDNAs for the cytidylyltransferase from a root cDNA library of Brassica napus by complementation in a yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455f1a98c12c1356861277c1a9418f9b
https://doi.org/10.1007/bf00021784
https://doi.org/10.1007/bf00021784
Autor:
Dallas P. Veitch, Rosemary B. Cornell
Publikováno v:
Biochemistry. 35:10743-10750
The effect of mutations in the proposed catalytic domain of CTP:phosphocholine cytidylyltransferase was investigated by constructing the single mutants CT-S91 and CT-C114 from the double mutant CT-S91C114, previously shown to have 4-fold lower than w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a698dc077e2cb888bf6cdff9b85b29
https://doi.org/10.1021/bi960402c
https://doi.org/10.1021/bi960402c
Autor:
Yuli Wang, Claudia Kent
Publikováno v:
Journal of Biological Chemistry. 270:17843-17849
To investigate the role of phosphorylation and dephosphorylation in modulating the activity and location of CTP:phosphocholine cytidylyltransferase, we used site-directed mutagenesis to construct four mutant forms of cytidylyltransferase. These forms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b11f0c49b563524b625de9bae43e3c
https://doi.org/10.1074/jbc.270.30.17843
https://doi.org/10.1074/jbc.270.30.17843
Publikováno v:
Neurochemistry International. 26:477-487
In brain tissue in vivo peroxidized according to three model systems, we determined two microsomal enzyme activities involved in phospholipid biosynthesis. The first, short-term model, was based on the i.v. administration to normal rats, twice a day,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b15bd046067fa5df55e0ab87b5a195
https://doi.org/10.1016/0197-0186(94)00152-k
https://doi.org/10.1016/0197-0186(94)00152-k