Discovery and Characterization of MaK: A Novel Knottin Antimicrobial Peptide from Monochamus alternatus .

Autor: Han X; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Zhou T; Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China., Hu X; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Zhu Y; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Shi Z; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Chen S; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Liu Y; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Weng X; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Zhang F; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Key Laboratory of Integrated Pest Management in Ecological Forests, Fujian Province University, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Wu S; College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Fujian Colleges and Universities Engineering Research Institute of Conservation and Utilization of Natural Bioresources, Fujian Agriculture and Forestry, Fuzhou 350002, China.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 17; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 17.

Targeting the tumor vasculature with engineered cystine-knot miniproteins

Autor: Bonny Gaby Lui, Nadja Salomon, Joycelyn Wüstehube-Lausch, Matin Daneschdar, Hans-Ulrich Schmoldt, Özlem Türeci, Ugur Sahin

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Cystine-knot miniprotein are small, highly stable, disulfide-rich peptides with increasing potential as drugs and tumor imaging agents. Here the authors develop cystine-knot miniproteins targeting the vascular tumor marker EDB, and use them as probes

Externí odkaz: https://doaj.org/article/c061d37878214c01aa09489f0ac9d33c

Recombinant Production, NMR Solution Structure, and Membrane Interaction of the Phα1β Toxin, a TRPA1 Modulator from the Brazilian Armed Spider Phoneutria nigriventer .

Autor: Lyukmanova EN; Department of Biology, MSU-BIT Shenzhen University, Shenzhen 518172, China.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), 141701 Dolgoprudny, Russia.; Interdisciplinary Scientific and Educational School of Moscow University 'Molecular Technologies of the Living Systems and Synthetic Biology', Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Mironov PA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; Interdisciplinary Scientific and Educational School of Moscow University 'Molecular Technologies of the Living Systems and Synthetic Biology', Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Kulbatskii DS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), 141701 Dolgoprudny, Russia., Shulepko MA; Department of Biology, MSU-BIT Shenzhen University, Shenzhen 518172, China.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia., Paramonov AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia., Chernaya EM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; National Research University Higher School of Economics, 101000 Moscow, Russia., Logashina YA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia., Andreev YA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia., Kirpichnikov MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; Interdisciplinary Scientific and Educational School of Moscow University 'Molecular Technologies of the Living Systems and Synthetic Biology', Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia., Shenkarev ZO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 119997 Moscow, Russia.; Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), 141701 Dolgoprudny, Russia.; International Tomography Center SB RAS, 630090 Novosibirsk, Russia.

Publikováno v: Toxins [Toxins (Basel)] 2023 Jun 03; Vol. 15 (6). Date of Electronic Publication: 2023 Jun 03.

Pilot-phase PET/CT study targeting integrin α v β 6 in pancreatic cancer patients using the cystine-knot peptide-based ¹⁸ F-FP-R 0 1-MG-F2.

Autor: Nakamoto R; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA., Ferri V; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA., Duan H; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA., Hatami N; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA., Goel M; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA., Rosenberg J; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA., Kimura R; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5281, USA., Wardak M; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5281, USA., Haywood T; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5281, USA., Kellow R; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5281, USA., Shen B; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5281, USA., Park W; Division of Gastroenterology and Hepatology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5281, USA., Iagaru A; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA. aiagaru@stanford.edu., Gambhir SS; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA, 94305-5281, USA.; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5281, USA.

Publikováno v: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2022 Dec; Vol. 50 (1), pp. 184-193. Date of Electronic Publication: 2021 Nov 03.

Anti-angiogenic effects of two cystine-knot miniproteins from tomato fruit.

Autor: Cavallini C; Department of Biotechnology, University of Verona, Italy., Trettene M, Degan M, Delva P, Molesini B, Minuz P, Pandolfini T

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2011 Mar; Vol. 162 (6), pp. 1261-73.