Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases

Autor: Tse-Hua Tan, Ping-Chiang Lyu, Huai-Chia Chuang, Chih-Hsuan Lai, Co-Chih Chang

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7515, p 7515 (2020)

Cysteine-based protein tyrosine phosphatases (Cys-based PTPs) perform dephosphorylation to regulate signaling pathways in cellular responses. The hydrogen bonding network in their active site plays an important conformational role and supports the ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8de4f15b8ac553db618f4c8b45a23ce
https://doi.org/10.3390/ijms21207515