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pro vyhledávání: '"Cys, cysteine"'
Akademický článek
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Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44
http://www.sciencedirect.com/science/article/pii/S2211383521001775
http://www.sciencedirect.com/science/article/pii/S2211383521001775
Publikováno v:
Current Research in Toxicology
Current Research in Toxicology, Vol 2, Iss, Pp 72-81 (2021)
Current Research in Toxicology, Vol 2, Iss, Pp 72-81 (2021)
Graphical abstract
Highlights • The widely used medicinal herb Withania somnifera (Ashwagandha) has been recently reported to cause liver damage. • Withanone is a major metabolite of Ashwagandha. • Withanone was found to cause DNA damage.
Highlights • The widely used medicinal herb Withania somnifera (Ashwagandha) has been recently reported to cause liver damage. • Withanone is a major metabolite of Ashwagandha. • Withanone was found to cause DNA damage.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c0382a427d8e9bd988eba87ffbd1cc
https://doi.org/10.1016/j.crtox.2021.02.002
https://doi.org/10.1016/j.crtox.2021.02.002
Autor:
Prem Rajak, Sumedha Roy, Achintya Kumar Pal, Manas Paramanik, Moumita Dutta, Sayanti Podder, Saurabh Sarkar, Abhratanu Ganguly, Moutushi Mandi, Anik Dutta, Kanchana Das, Siddhartha Ghanty, Salma Khatun
Publikováno v:
Current Research in Toxicology, Vol 2, Iss, Pp 411-423 (2021)
Current Research in Toxicology
CURRENT RESEARCH IN TOXICOLOGY
Current Research in Toxicology
CURRENT RESEARCH IN TOXICOLOGY
Graphical abstract
Highlights • Inhalation of rotenone exposes lung surfactant proteins (SP) to this pesticide. • SP-A and SP-D provides protection from microbial infection. • SP-B and SP-C maintain structure and respiratory function of lu
Highlights • Inhalation of rotenone exposes lung surfactant proteins (SP) to this pesticide. • SP-A and SP-D provides protection from microbial infection. • SP-B and SP-C maintain structure and respiratory function of lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f2cd79baf46b999beeed39c977274d
http://www.sciencedirect.com/science/article/pii/S2666027X21000414
http://www.sciencedirect.com/science/article/pii/S2666027X21000414
Autor:
Terry B. Ruskoski, Amie K. Boal
Publikováno v:
The Journal of Biological Chemistry
In most organisms, transition metal ions are necessary cofactors of ribonucleotide reductase (RNR), the enzyme responsible for biosynthesis of the 2′-deoxynucleotide building blocks of DNA. The metal ion generates an oxidant for an active site cyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09cecf12ddc55c7368f1020d6a618d2
http://europepmc.org/articles/PMC8463856
http://europepmc.org/articles/PMC8463856
Autor:
Kavita Bhagat, Preet Mohinder Singh Bedi, Atamjit Singh, Amit Duggal, Puja Gulati, Komalpreet Kaur, Shilpa Dudhal, Harmandeep Kaur Gulati, Jatinder Vir Singh, Jaspreet Kaur, Harbinder Singh, Nitish Kumar
Publikováno v:
Phytomedicine Plus
Phytomedicine Plus, Vol 1, Iss 4, Pp 100083-(2021)
Phytomedicine Plus, Vol 1, Iss 4, Pp 100083-(2021)
Background Lack of treatment of novel Coronavirus disease led to the search of specific antivirals that are capable to inhibit the replication of the virus. The plant kingdom has demonstrated to be an important source of new molecules with antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939ef681815567886f1f3e386c85714b
http://europepmc.org/articles/PMC8180089
http://europepmc.org/articles/PMC8180089
Autor:
Adesh K. Saini, Ashu Mohammad, Reena V. Saini, Deepak Sharma, Christine C. Winterbourn, Rakesh Kumar, Arpit Gupta, Neeraj K. Saini, Priyanka Thakur
Publikováno v:
Redox Biology
Redox Biology, Vol 37, Iss, Pp 101738-(2020)
Redox Biology, Vol 37, Iss, Pp 101738-(2020)
Peroxiredoxins (Prxs) are antioxidant proteins that are involved in cellular defence against reactive oxygen species and reactive nitrogen species. Humans have six peroxiredoxins, hPrxI-VI, out of which hPrxI and hPrxII belongs to the typical 2-Cys c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e078256bef804b260818a42b673e244e
http://europepmc.org/articles/PMC7530344
http://europepmc.org/articles/PMC7530344
Autor:
Hangel, Gilbert, Cadrien, Cornelius, Lazen, Philipp, Furtner, Julia, Lipka, Alexandra, Hečková, Eva, Hingerl, Lukas, Motyka, Stanislav, Gruber, Stephan, Strasser, Bernhard, Kiesel, Barbara, Mischkulnig, Mario, Preusser, Matthias, Roetzer, Thomas, Wöhrer, Adelheid, Widhalm, Georg, Rössler, Karl, Trattnig, Siegfried, Bogner, Wolfgang
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss, Pp 102433-(2020)
NeuroImage : Clinical
NeuroImage : Clinical
Graphical abstract
Highlights • We demonstrated reliable and fast whole-brain 3D-MRSI of high-grade gliomas at 7T. • tCho, Gln, and Gly were increased in contrast-enhancing tumor tissue. • Results corresponded well to clinical data, but sh
Highlights • We demonstrated reliable and fast whole-brain 3D-MRSI of high-grade gliomas at 7T. • tCho, Gln, and Gly were increased in contrast-enhancing tumor tissue. • Results corresponded well to clinical data, but sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::28bb3c72f0f60bade3cf746269e3a9c2
http://www.sciencedirect.com/science/article/pii/S2213158220302709
http://www.sciencedirect.com/science/article/pii/S2213158220302709
Autor:
Rocco Pizzarelli, Andrea Barberis, Antonino Cattaneo, Enrico Cherubini, Enrica Maria Petrini, Marilena Griguoli, Paola Zacchi
Publikováno v:
Neuroscience
To be highly reliable, synaptic transmission needs postsynaptic receptors (Rs) in precise apposition to the presynaptic release sites. At inhibitory synapses, the postsynaptic protein gephyrin self-assembles to form a scaffold that anchors glycine an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90608b4dcd3ea52993f032731e6b4192
https://hdl.handle.net/11384/126845
https://hdl.handle.net/11384/126845
Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications
Autor:
Valentina Villalobos Coa, Lissette Jiménez, Vito Lubes, Giuseppe Lubes, Carlos Ciangherotti, Edgar Del Carpio, Lino Hernández
Publikováno v:
Coordination Chemistry Reviews
Highlights • Vanadium history and industrial applications. • Recent research on metal vanadium complexes with amino acids. • Vanadium complexes with amino acids and their properties. • Vanadium complexes are promising candidates as metallopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7069072523dc8edd6a7a45ad1672583b
https://doi.org/10.1016/j.ccr.2018.06.002
https://doi.org/10.1016/j.ccr.2018.06.002