Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Cyrus Vaziri"'
Autor:
Xing Cheng, Jing An, Jitong Lou, Qisheng Gu, Weimin Ding, Gaith Nabil Droby, Yilin Wang, Chenghao Wang, Yanzhe Gao, Jay Ramanlal Anand, Abigail Shelton, Andrew Benson Satterlee, Breanna Mann, Yun-Chung Hsiao, Chih-Wei Liu, Kun Lu, Shawn Hingtgen, Jiguang Wang, Zhaoliang Liu, C. Ryan Miller, Di Wu, Cyrus Vaziri, Yang Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Almost all Glioblastoma (GBM) are either intrinsically resistant to the chemotherapeutical drug temozolomide (TMZ) or acquire therapy-induced mutations that cause chemoresistance and recurrence. The genome maintenance mechanisms responsible
Externí odkaz:
https://doaj.org/article/30b03460503c40948e61ba53f8ff91ba
Autor:
Ye S. Lee, Jennifer E. Klomp, Clint A. Stalnecker, Craig M. Goodwin, Yanzhe Gao, Gaith N. Droby, Cyrus Vaziri, Kirsten L. Bryant, Channing J. Der, Adrienne D. Cox
Publikováno v:
Genes & Cancer. 14:30-49
Autor:
Melissa A. Troester, Katherine A. Hoadley, Cyrus Vaziri, Charles M. Perou, Gaorav P. Gupta, Michael I. Love, Erin L. Kirk, Alina M. Hamilton, Xiaohua Gao, Alex Lockhart, Markia A. Smith, Linnea T. Olsson, Sarah C. Van Alsten, Andrea Walens
Background:Aberrant expression of DNA repair pathways such as homologous recombination (HR) can lead to DNA repair imbalance, genomic instability, and altered chemotherapy response. DNA repair imbalance may predict prognosis, but variation in DNA rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26082be2ddd4e39d8e04cca6b3b9f150
https://doi.org/10.1158/1055-9965.c.6660312.v1
https://doi.org/10.1158/1055-9965.c.6660312.v1
Autor:
Melissa A. Troester, Katherine A. Hoadley, Cyrus Vaziri, Charles M. Perou, Gaorav P. Gupta, Michael I. Love, Erin L. Kirk, Alina M. Hamilton, Xiaohua Gao, Alex Lockhart, Markia A. Smith, Linnea T. Olsson, Sarah C. Van Alsten, Andrea Walens
Supplementary Figure from RNA-Based Classification of Homologous Recombination Deficiency in Racially Diverse Patients with Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cd3e65fc8112cd41e42cf4195fbcb1
https://doi.org/10.1158/1055-9965.23099349.v1
https://doi.org/10.1158/1055-9965.23099349.v1
Autor:
Matthew C. Fleming, Lilly F. Chiou, Percy P. Tumbale, Gaith N. Droby, Jiwoong Lim, Jacqueline L. Norris-Drouin, Jason G. Williams, Kenneth H. Pearce, R. Scott Williams, Cyrus Vaziri, Albert A. Bowers
Publikováno v:
J Med Chem
MAGE proteins are well-known cancer testis antigens (CTAs) that are selectively expressed in cancer and germline cells. Characterized by the highly conserved MAGE homology domain (MHD), MAGEs are increasingly reported to play pivotal roles in promoti
Autor:
Yanzhe Gao, Elizabeth Mutter-Rottmayer, Alicia M. Greenwalt, Dennis Goldfarb, Feng Yan, Yang Yang, Raquel C. Martinez-Chacin, Kenneth H. Pearce, Satoshi Tateishi, Michael B. Major, Cyrus Vaziri
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
RAD18 is an important protein in trans-lesion synthesis, an error-prone damage-tolerant mode of DNA replication. Here the authors show that MAGE-A4 stabilizes RAD18 and allows cancer cells to maintain on-going DNA synthesis in the face of genotoxic i
Externí odkaz:
https://doaj.org/article/0e5d0907f6a14928a23a27cda5802f8e
Autor:
Jay Anand, Lilly Chiou, Carly Sciandra, Xingyuan Zhang, Jiyong Hong, Di Wu, Pei Zhou, Cyrus Vaziri
Publikováno v:
NAR Cancer. 5
DNA damage tolerance and mutagenesis are hallmarks and enabling characteristics of neoplastic cells that drive tumorigenesis and allow cancer cells to resist therapy. The ‘Y-family’ trans-lesion synthesis (TLS) DNA polymerases enable cells to rep
Publikováno v:
Oncogene
Mutagenesis is a key hallmark and enabling characteristic of cancer cells, yet the diverse underlying mutagenic mechanisms that shape cancer genomes are not understood. This review will consider the emerging challenge of determining how DNA damage re
Autor:
Breanna Mann, Xiaopei Zhang, Noah Bell, Adebimpe Adefolaju, Morrent Thang, Rajaneekar Dasari, Krishna Kanchi, Alain Valdivia, Yang Yang, Andrew Buckley, Vivien Lettry, Carolyn Quinsey, Yasmeen Rauf, David Kram, Noah Cassidy, Cyrus Vaziri, David L. Corcoran, Stephen Rego, Yuchao Jiang, Lee M. Graves, Denise Dunn, Scott Floyd, Albert Baldwin, Shawn Hingtgen, Andrew B. Satterlee
Publikováno v:
Cell Reports Medicine. :101042
Autor:
Andrea Walens, Sarah C. Van Alsten, Linnea T. Olsson, Markia A. Smith, Alex Lockhart, Xiaohua Gao, Alina M. Hamilton, Erin L. Kirk, Michael I. Love, Gaorav P. Gupta, Charles M. Perou, Cyrus Vaziri, Katherine A. Hoadley, Melissa A. Troester
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 31(12)
Background: Aberrant expression of DNA repair pathways such as homologous recombination (HR) can lead to DNA repair imbalance, genomic instability, and altered chemotherapy response. DNA repair imbalance may predict prognosis, but variation in DNA re