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pro vyhledávání: '"Cyrus Tabatabay"'
Publikováno v:
Biopharmaceutics of Ocular Drug Delivery ISBN: 9780429284755
Biopharmaceutics of Ocular Drug Delivery
Biopharmaceutics of Ocular Drug Delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90a0de824aecc913df8caf5d1c6bccc2
https://doi.org/10.1201/9780429284755-7
https://doi.org/10.1201/9780429284755-7
Autor:
Jorge Heller, M. Savoldelli, Cyrus Tabatabay, R.A. Bejjani, François D'Hermies, Francine Behar-Cohen, Robert Gurny, Stéphanie Ponsart, Suzanne Einmahl
Publikováno v:
Journal of Biomedical Materials Research. :44-53
The biocompatibility of autocatalyzed poly(ortho ester) (POE70LA30), a viscous, hydrophobic, bioerodible polymer, was investigated. POE70LA30 was synthesized, sterilized by gamma irradiation, and injected in rabbit eyes at adequate volumes through su
Publikováno v:
Macromolecular Symposia. 172:73-86
A poly(ortho ester) (POE) has been investigated as a carrier for controlled delivery in intraocular therapy. The intraocular biocompatibility of POE was assessed in the rabbit after intravitreal as well as suprachoroidal injections. In both cases, th
Autor:
Suzanne Einmahl, Robert Gurny, François D'Hermies, M. Savoldelli, Cyrus Tabatabay, Francine Behar-Cohen, J. Heller, D. Chauvaud
Publikováno v:
Journal of Biomedical Materials Research. 50:566-573
The biocompatibility of a viscous, hydrophobic, bioerodible poly(ortho ester) (POE) intended for intraocular application was investigated. POE was evaluated as a blank carrier and as containing modulators of degradation. Each formulation was injected
Autor:
James M. Anderson, Robert Gurny, Monia Zignani, Cyrus Tabatabay, S. F. Bernatchez, T. Le Minh
Publikováno v:
Journal of Biomedical Materials Research. 39:277-285
The biocompatibility of a viscous poly(ortho ester) (POE) intended for prolonged intraocular drug delivery was studied. This hydrophobic and bioerodable carrier was subconjunctivally injected in rabbits and evaluated both clinically and histologicall
Publikováno v:
Progress in Polymer Science. 23:563-580
Autor:
J. Heller, S. F. Bernatchez, Monia Zignani, Alain Merkli, Robert Gurny, Martina Barbara Sintzel, Werner Kloeti, Cyrus Tabatabay
Publikováno v:
Journal of Controlled Release. 48:115-129
After a brief historical overview of the development of three families of poly(ortho esters) (POEs), the physico-chemical characteristics, drug release properties and biocompatibility of the third generation is discussed. Its synthesis is based on a
Publikováno v:
Drug Development and Industrial Pharmacy, Vol. 23, No 9 (1997) pp. 857-878
A survey was made of the influence of irradiation sterilization on relevant natural, semisynthetic, and synthetic polymers used for drug carrier system. The first part of the review deals with some general aspects of irradiation treatment and its use
Publikováno v:
Advanced Drug Delivery Reviews, Vol. 16 (1995) pp. 51-60
The efficacy of ophthalmic semi-solid hydrogels is mostly based on an increase of ocular residence time, via enhanced viscosity and mucoadhesive properties. Preformed and in particular in situ gelling systems improve bioavailability and decrease the
Publikováno v:
Journal of Controlled Release. 33:415-421
Semi-solid poly(ortho esters) (POE) prepared by a transesterification reaction between trimethyl orthoacetate and 1,2,6-hexanetriol were investigated as injectable bioerodible polymers for the controlled release of 5-fluorouracil (5-FU) and mitomycin