Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Cyrus M Ghajar"'
Autor:
Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Anson T Ku, Scott Wilkinson, Hanbing Song, Nicholas J Brady, Robert A Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H Bielas, Raphael Gottardo, David S Rickman, Franklin W Huang, Cyrus M Ghajar, Peter S Nelson, Adam G Sowalsky, Manu Setty, Andrew C Hsieh
Publikováno v:
eLife, Vol 11 (2022)
Advanced prostate malignancies are a leading cause of cancer-related deaths in men, in large part due to our incomplete understanding of cellular drivers of disease progression. We investigate prostate cancer cell dynamics at single-cell resolution f
Externí odkaz:
https://doaj.org/article/df92bed0fdd1409a988b59a78b4ffbca
Autor:
Ryann E. Shor, Jinxiang Dai, Sun‐Young Lee, Laura Pisarsky, Irina Matei, Serena Lucotti, David Lyden, Mina J. Bissell, Cyrus M. Ghajar
Publikováno v:
Molecular Oncology, Vol 16, Iss 1, Pp 130-147 (2022)
Dormant, disseminated tumor cells (DTCs) are thought to be the source of breast cancer metastases several years or even decades after initial treatment. To date, a selective therapy that leads to their elimination has not been discovered. While dorma
Externí odkaz:
https://doaj.org/article/a3a3a49dc68740cfb9870a78fd1324e9
Autor:
Candice A. Grzelak, Cyrus M. Ghajar
Publikováno v:
ImmunoHorizons. 7:64-70
The human ubiquitin C promoter (UBC)–driven GFP-transgenic mouse (UBC-GFP) transgene integration site was mapped recently to chromosome 17, linked closely to the MHC locus. In this study, we demonstrate a functional consequence of this insertion si
Autor:
David Lyden, Cyrus M. Ghajar, Ana Luísa Correia, Julio A. Aguirre-Ghiso, Shang Cai, Maria Rescigno, Peiyuan Zhang, Guohong Hu, Sarah-Maria Fendt, Adrienne Boire, Ralph R. Weichselbaum, Rohan R. Katipally
Publikováno v:
Cancer Cell
Metastasis, the major cause of cancer death, represents one of the major challenges in oncology. Scientists are still trying to understand the biological basis underlying the dissemination and outgrowth of tumor cells, why these cells can remain dorm
Autor:
Sarah B. Crist, Travis Nemkov, Ruth F. Dumpit, Jinxiang Dai, Stephen J. Tapscott, Lawrence D. True, Alexander Swarbrick, Lucas B. Sullivan, Peter S. Nelson, Kirk C. Hansen, Cyrus M. Ghajar
Publikováno v:
Nature Cell Biology. 24:538-553
Autor:
Candice Alexandra Grzelak, Kamya Rajaram, Jinxiang Dai, Ryann E Shor, Alister P W Funnell, Emma E Lederer, Andrea R. Lim, Slobodan Beronja, Cyrus M. Ghajar, Erica T. Goddard, Jeanna Kim
Publikováno v:
Cancer cell. 40(1)
Autor:
Jinxiang Dai, Patrick J. Cimino, Kenneth H. Gouin, Candice A. Grzelak, Alexander Barrett, Andrea R. Lim, Annalyssa Long, Stephanie Weaver, Lindsey T. Saldin, Aiyedun Uzamere, Vera Schulte, Nigel Clegg, Laura Pisarsky, David Lyden, Mina J. Bissell, Simon Knott, Alana L. Welm, Jason H. Bielas, Kirk C. Hansen, Frank Winkler, Eric C. Holland, Cyrus M. Ghajar
Publikováno v:
Nature Cancer. 3:25-42
Although dormancy is thought to play a key role in the metastasis of breast tumor cells to the brain, our knowledge of the molecular mechanisms regulating disseminated tumor cell (DTC) dormancy in this organ is limited. Here using serial intravital i
Autor:
Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Anson T Ku, Scott Wilkinson, Hanbing Song, Nicholas J Brady, Robert A Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H Bielas, Raphael Gottardo, David S Rickman, Franklin W Huang, Cyrus M Ghajar, Peter S Nelson, Adam G Sowalsky, Manu Setty, Andrew C Hsieh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f4bfb2220e32e7121b164ee228d7fc3
https://doi.org/10.7554/elife.79076.sa2
https://doi.org/10.7554/elife.79076.sa2
Autor:
David Lyden, Laura Pisarsky, Cyrus M. Ghajar, Irina Matei, Sun-Young Lee, Serena Lucotti, Mina J. Bissell, Jinxiang Dai, Ryann E Shor
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 16, Iss 1, Pp 130-147 (2022)
Molecular Oncology, Vol 16, Iss 1, Pp 130-147 (2022)
Dormant, disseminated tumor cells (DTCs) are thought to be the source of breast cancer metastases several years or even decades after initial treatment. To date, a selective therapy that leads to their elimination has not been discovered. While dorma
Autor:
Alexandre A. Germanos, Sonali Arora, Ye Zheng, Erica T. Goddard, Ilsa M. Coleman, Anson T. Ku, Scott Wilkinson, Robert A. Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H. Bielas, Raphael Gottardo, Cyrus M. Ghajar, Peter S. Nelson, Adam G. Sowalsky, Manu Setty, Andrew C. Hsieh
SummaryAdvanced prostate malignancies are a leading cause of cancer-related deaths in men, in large part due to our incomplete understanding of cellular drivers of disease progression. We investigated prostate cancer cell dynamics at single-cell reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585809df8017aebd0426274fec2c7f71
https://doi.org/10.1101/2022.03.02.482711
https://doi.org/10.1101/2022.03.02.482711