Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Cyrus Levinthal"'
Publikováno v:
Science. 259:960-963
To investigate the mechanism of interaction of the toxin colicin E1 with membranes, three cysteine substitution mutants and the wild type of the channel-forming fragment were spin labeled at the unique thiol. Time-resolved interaction of these labele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172ef1345b07ac465ca53ecfd1470a5c
https://doi.org/10.1126/science.8382373
https://doi.org/10.1126/science.8382373
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 11:254-262
The molecularity of the ion channel formed by peptide fragments of colicin has taken on particular significance since the length of the active peptide has been shown to be less than 90 amino acids and the lumen size at least 8 A. Cell survival experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e880e8a2fc1ce4183a54ed2c7552bc
https://doi.org/10.1002/prot.340110404
https://doi.org/10.1002/prot.340110404
Autor:
Huajun Wang, Cyrus Levinthal
Publikováno v:
Journal of Computational Chemistry. 12:868-871
An algorithm is presented for calculating the solvent accessible surface area of proteins using a three-dimensional grid. Since it requires only calculations based on single atomic positions, the algorithm is easy to be vectorized. It has been implem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d29afe3c7432f5aedc154131f8a4d6
https://doi.org/10.1002/jcc.540120712
https://doi.org/10.1002/jcc.540120712
Publikováno v:
Proteins. 11(4)
We describe the design, construction, and performance of a special purpose, hardwired accelerator for molecular mechanical calculations called FASTRUN. The processor was designed at Columbia University in 1984, constructed in the Instrumentation Divi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3cdd7882a909a49e8f917b02001ce4
https://pubmed.ncbi.nlm.nih.gov/1758880
https://pubmed.ncbi.nlm.nih.gov/1758880
Autor:
Cyrus Levinthal, Barry A. Allen
Publikováno v:
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 14(5)
The paper describes the history of tracing activities in the Levinthal lab from 1965 to the present. It also focuses on the evolution of electron micrograph (EM) tracing from early hand tracing reconstruction to the current, nearly fully automated CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e01058a77d44537f0769a8039448acc
https://pubmed.ncbi.nlm.nih.gov/2224830
https://pubmed.ncbi.nlm.nih.gov/2224830
Publikováno v:
Microvascular Research. 27:96-109
Graph theory methods were used to analyze the topology of the renal glomerular capillary network using data both from a serial reconstruction of a rat glomerulus and from the literature. The graphs obtained were tested for planarity, and all but one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b58f4600fbfc80690c34d122069d43
https://doi.org/10.1016/0026-2862(84)90044-x
https://doi.org/10.1016/0026-2862(84)90044-x
Publikováno v:
Neuron. 1:367-376
To search for genes involved in determining the morphology of individual neuronal types, a cDNA library was constructed from postnatal day 13 mouse cerebellum. From this library, 2 clones, L7 and L19, were isolated by a differential hybridization pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3493a01545228c95da46fa0c96344f3
https://doi.org/10.1016/0896-6273(88)90186-9
https://doi.org/10.1016/0896-6273(88)90186-9
Autor:
George L. Wilcox, Stephen C. Harvey, Florante A. Quiocho, Gerald M. Maggiora, Cyrus Levinthal, J. Andrew McCammon
Publikováno v:
Journal of Computer-Aided Molecular Design. 1:271-281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7b0bfe165e82e9c3895f44466f1561
https://doi.org/10.1007/bf01677276
https://doi.org/10.1007/bf01677276
Autor:
Cyrus Levinthal
Publikováno v:
Annals of the New York Academy of Sciences. 426:171-180
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69022c13e56ee97a470bccd1cdc15db9
https://doi.org/10.1111/j.1749-6632.1984.tb16519.x
https://doi.org/10.1111/j.1749-6632.1984.tb16519.x
Publikováno v:
Proteins: Structure, Function, and Genetics. 6:294-305
Colicin E1 is an E. coli plasmid-encoded water-soluble protein that spontaneously inserts into lipid membranes to form a voltage-gated ion channel. We have employed a novel approach in which site-directed mutagenesis is used to provide highly specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ba9bad4924960d8b56733b56d513c2
https://doi.org/10.1002/prot.340060312
https://doi.org/10.1002/prot.340060312