Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Cyrus Karkaria"'
Autor:
Stephen T. Sonis, Brynmor A. Watkins, William J. Larochelle, Cyrus Karkaria, Gulshan Ara, Thomas R Hawthorne, Haihong Zhong
Publikováno v:
International Journal of Radiation Biology. 84:401-412
Velafermin (recombinant human fibroblast growth factor-20, rhFGF-20) has been shown to reduce the severity and duration of mucositis in preclinical acute (single dose) radiation and chemotherapy/radiation models of oral mucositis. Our present study a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af83fa3fe450f96030be8864b9518f41
https://doi.org/10.1080/09553000802007601
https://doi.org/10.1080/09553000802007601
Publikováno v:
International journal of pharmaceutics. 378(1-2)
This study discusses the effect of key factors like containers, buffers and the freeze (controlled vs. flash freezing) and thawing processes on the stability of a therapeutic protein fibroblast growth factor 20 (FGF-20). The freezing profiles monitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1e55a2348a1df2f01b4e4ba86379fe
https://pubmed.ncbi.nlm.nih.gov/19505546
https://pubmed.ncbi.nlm.nih.gov/19505546
Publikováno v:
Current pharmaceutical biotechnology. 10(6)
The purpose of this study was to dramatically enhance the solubility (> 400 fold) and stability of a therapeutic protein (Fibroblast Growth Factor 20) and to perform detailed biophysical characterization for the optimization of its formulation. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a251a4dc96880701b958df957a7293
https://pubmed.ncbi.nlm.nih.gov/19619121
https://pubmed.ncbi.nlm.nih.gov/19619121
Autor:
Firoz Mistry, Scott W. Reid, Jolanda Schreurs, Rashid Syed, Robert M. Stroud, Bradley A. Katz, David J. Matthews, Mark Dreyer, Laura Savel, Karen C. Sitney, Lutz B. Giebel, Joan C. Egrie, Hangjun Zhan, Cuiwei Li, Kirk Hayenga, Cyrus Karkaria, Janet Cheetham, Kenneth H. Aoki, Gary Koe, Beishan Liu
Publikováno v:
Protein engineering. 12(6)
4 To whom correspondence should be addressed The extracellular ligand-binding domain (EPObp) of the human EPO receptor (EPOR) was expressed both in CHO (Chinese Hamster Ovary) cells and in Pichia pastoris. The CHO and yeast expressed receptors showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e075ae637e1734e4dadf9bfc5f1a80
https://pubmed.ncbi.nlm.nih.gov/10388848
https://pubmed.ncbi.nlm.nih.gov/10388848