Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cyrus F. Khambatta"'
Autor:
Scott M. Turner, Lindsay S. Roberts, Marc K. Hellerstein, Nicholas A. Floreani, John C. Price, William E. Holmes, Mahalakshmi Shankaran, Cyrus F. Khambatta, Kelvin W. Li, Matthew D. Bruss, Marcy Dalidd
Publikováno v:
Molecular & Cellular Proteomics : MCP
Calorie restriction (CR) promotes longevity. A prevalent mechanistic hypothesis explaining this effect suggests that protein degradation, including mitochondrial autophagy, is increased with CR, removing damaged proteins and improving cellular fitnes
Autor:
Marc K. Hellerstein, Cyrus F. Khambatta, Airlia C. S. Thompson, Ishita Aggarwal, Matthew D. Bruss
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 300:E735-E745
Calorie restriction (CR) reduces the rate of cell proliferation in mitotic tissues. It has been suggested that this reduction in cell proliferation may mediate CR-induced increases in longevity. However, the mechanisms that lead to CR-induced reducti
Autor:
William E. Holmes, Cyrus F. Khambatta, Clinton M. Astle, Matthew D. Bruss, Airlia C. S. Thompson, Marc Colangelo, Marcy Dalidd, John C. Price, Lindsay S. Roberts, Marc K. Hellerstein, David E. Harrison
Publikováno v:
Aging Cell
Summary Combating the social and economic consequences of a growing elderly population will require the identification of interventions that slow the development of age‐related diseases. Preserved cellular homeostasis and delayed aging have been pr
Autor:
D. J. Roohk, Marc K. Hellerstein, Ho Leung, Charles A. Harris, Smita Mascharak, Cyrus F. Khambatta
Publikováno v:
Endocrinology. 154(4)
The glucocorticoid (GC) receptor (GR) has multiple effector mechanisms, including dimerization-mediated transactivation of target genes via DNA binding and transcriptional repression mediated by protein-protein interactions. Much attention has been f
Publikováno v:
The FASEB Journal. 24
Calorie restriction (CR) increases longevity and retards the development of many chronic diseases, but the underlying metabolic signals are poorly understood. Increased fatty acid (FA) oxidation and reduced FA synthesis have been hypothesized to be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d996b5885a94964a1bb8d4f8bf55de7
https://europepmc.org/articles/PMC4056782/
https://europepmc.org/articles/PMC4056782/