Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cyrus Cheung"'
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 4, Iss 5, Pp 401-410 (2024)
Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The disease is characterized by the abnormal accumulation of amyloid β (Aβ) protein creating neuritic plaques, hyperphosphorylated tau (p-tau) protein forming intracellular tang
Externí odkaz:
https://doaj.org/article/2cb8f8113bc0467cbebea2f05de6f393
Autor:
Sanaya N. Shroff, Eric Lowet, Sudiksha Sridhar, Howard J. Gritton, Mohammed Abumuaileq, Hua-An Tseng, Cyrus Cheung, Samuel L. Zhou, Krishnakanth Kondabolu, Xue Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Rhythmic neural network activity has been broadly linked to behavior. However, it is unclear how membrane potentials of individual neurons track behavioral rhythms, even though many neurons exhibit pace-making properties in isolated brain ci
Externí odkaz:
https://doaj.org/article/ccfc97b3d7934471b978e4eb372e7ff0
Autor:
Eric Lowet, Daniel J. Sheehan, Ulises Chialva, Rodrigo De Oliveira Pena, Rebecca A. Mount, Sheng Xiao, Samuel L. Zhou, Hua-an Tseng, Howard Gritton, Sanaya Shroff, Krishnakanth Kondabolu, Cyrus Cheung, Yangyang Wang, Kiryl D. Piatkevich, Edward S. Boyden, Jerome Mertz, Michael E. Hasselmo, Horacio G. Rotstein, Xue Han
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112906- (2023)
Summary: Hippocampal CA1 neurons generate single spikes and stereotyped bursts of spikes. However, it is unclear how individual neurons dynamically switch between these output modes and whether these two spiking outputs relay distinct information. We
Externí odkaz:
https://doaj.org/article/b5652001c01443b4ab56188e0408577e
Hippocampal network activity at theta frequencies (5-10Hz) is important for behavior. However, it remains unclear how behaviorally-relevant network theta rhythms arise and interact with cellular dynamics to dictate spike timing. We performed membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc18bfab3c0b3b688369dda8f2bed9a9
https://doi.org/10.1101/2022.11.14.516448
https://doi.org/10.1101/2022.11.14.516448
Autor:
Eric Lowet, Daniel J. Sheehan, Rebecca A. Mount, Sheng Xiao, Samuel L. Zhou, Hua-an Tseng, Howard Gritton, Sanaya Shroff, Krishnakanth Kondabolu, Cyrus Cheung, Jerome Mertz, Michael E. Hasselmo, Xue Han
Hippocampal neurons generate either single spikes or stereotyped bursts of spikes known as complex spikes. Although single and complex spikes co-occur in the same neuron, their contribution to information processing remains unclear. We analyzed hippo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688fbbc4286f2e48e12b8cd54d3365d9
https://doi.org/10.1101/2022.04.06.487256
https://doi.org/10.1101/2022.04.06.487256
Publikováno v:
Cell reports
SUMMARY Dopamine degeneration in Parkinson’s disease (PD) dysregulates the striatal neural network and causes motor deficits. However, it is unclear how altered striatal circuits relate to dopamine-acetylcholine chemical imbalance and abnormal loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606fc5abe9c59204a5d5c648e8cdefa2
http://europepmc.org/articles/PMC8820590
http://europepmc.org/articles/PMC8820590
The objective of this research is to synthesize core-shell nano-structured metal oxide materials and investigate their structural, electronic and optical properties to understand the microscopic pathways governing the energy conversion process, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb23903a7feab22234eed1145aa6c0f8
https://doi.org/10.2172/1234453
https://doi.org/10.2172/1234453