Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Cyrine E Haidar"'
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/5b86d78c843c43108c539809f2da76de
Autor:
Amy J. Turner, Cyrine E. Haidar, Wenjian Yang, Erin C. Boone, Steven M. Offer, Philip E. Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 1, Pp n/a-n/a (2024)
Abstract The DPYD gene encodes dihydropyrimidine dehydrogenase, the rate‐limiting enzyme for the metabolism of fluoropyrimidines 5‐fluorouracil and capecitabine. Genetic variants in DPYD have been associated with altered enzyme activity, therefor
Externí odkaz:
https://doaj.org/article/5ba0596362e44f6ea49932ac67879e47
Autor:
Kelly E. Caudle, Katrin Sangkuhl, Michelle Whirl‐Carrillo, Jesse J. Swen, Cyrine E. Haidar, Teri E. Klein, Roseann S. Gammal, Mary V. Relling, Stuart A. Scott, Daniel L. Hertz, Henk‐Jan Guchelaar, Andrea Gaedigk
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 1, Pp 116-124 (2020)
Translating CYP2D6 genotype to metabolizer phenotype is not standardized across clinical laboratories offering pharmacogenetic (PGx) testing and PGx clinical practice guidelines, such as the Clinical Pharmacogenetics Implementation Consortium (CPIC)
Externí odkaz:
https://doaj.org/article/eaaeaa1c4346425da8183e2137c63c57
Autor:
Dylan E. Graetz, Elizabeth Sniderman, Cesar Villegas, Iman Ragab, Aliaksandra Laptsevich, Biemba Maliti, Gita Naidu, Hui Zhang, Pascale Gassant, Luciana Nunes, Daniela Arce, Jacqueline Montoya Vasquez, Ramandeep S Arora, Ana P Alcasabas, Desy Rusmawatiningtyas, Muhammad Rafie Raza, Syed A Hamid, Pablo Velasco, Joyce Kambugu, Anna Vinitsky, Nancy S. Bolous, Cyrine E. Haidar, Laure Bihannic, Diana Sa da Bandeira, Jade X Wang, Dongfang Li, Flavia Graca, Aksana Vasilyeva, Harry Lesmana, Carlos R Galindo, Asya Agulnik, Daniel C. Moreira
Publikováno v:
Global Qualitative Nursing Research, Vol 9 (2022)
Historically, qualitative research has complemented quantitative biologic and epidemiologic studies to provide a more complete understanding of pandemics. The COVID-19 pandemic has generated unique and novel challenges for qualitative researchers, wh
Externí odkaz:
https://doaj.org/article/83916d5ad5354259831cabfbec29cb58
Autor:
Jenny Q Nguyen, Kristine R Crews, Ben T Moore, Nancy M Kornegay, Donald K Baker, Murad Hasan, Patrick K Campbell, Shannon M Dean, Mary V Relling, James M Hoffman, Cyrine E Haidar
Publikováno v:
Journal of the American Medical Informatics Association. 30:132-138
Thoughtful integration of interruptive clinical decision support (CDS) alerts within the electronic health record is essential to guide clinicians on the application of pharmacogenomic results at point of care. St. Jude Children’s Research Hospital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70eb0a75678696f752f57c6a09417300
https://doi.org/10.1093/jamia/ocac187
https://doi.org/10.1093/jamia/ocac187
Publikováno v:
Annual Review of Genomics and Human Genetics. 23:449-473
Pharmacogenomic testing can be an effective tool to enhance medication safety and efficacy. Pharmacogenomically actionable medications are widely used, and approximately 90–95% of individuals have an actionable genotype for at least one pharmacogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bffba0e19dca379e32901f6ea0c487d
https://doi.org/10.1146/annurev-genom-111621-102737
https://doi.org/10.1146/annurev-genom-111621-102737
Autor:
Sarah A. Morris, Wenjian Yang, Mary V. Relling, Donald K. Baker, Randall T. Hayden, Ulrich Broeckel, Kristine R. Crews, Cyrine E. Haidar, Clifford M. Takemoto
Publikováno v:
Pharmacogenet Genomics
Glucose-6-phosphate-dehydrogenase (G6PD) deficiency is a common X-linked enzyme disorder associated with hemolytic anemia after exposure to fava beans or certain medications. Activity testing is the gold standard for detecting G6PD deficiency; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f1455180ae595e369b971ba1c9e65b
https://doi.org/10.1097/fpc.0000000000000456
https://doi.org/10.1097/fpc.0000000000000456
Autor:
Caroline Flora Samer, Larisa H. Cavallari, Andrew A. Monte, Andrew A. Somogyi, Rachel Huddart, Evan D. Kharasch, Kelly E. Caudle, Gualberto Ruaño, J. Steven Leeder, Andrea Gaedigk, Sara L. Van Driest, Cynthia A. Prows, Kristine R. Crews, Teri E. Klein, Todd C. Skaar, Henry M. Dunnenberger, Cyrine E. Haidar, Daniel J. Müller, John T. Callaghan, Mohamed Nagy, Katrin Sangkuhl
Publikováno v:
Clin Pharmacol Ther
Clinical Pharmacology and Therapeutics (2021)
Clinical Pharmacology and Therapeutics (2021)
Opioids are mainly used to treat both acute and chronic pain. Several opioids are metabolized to some extent by CYP2D6 (codeine, tramadol, hydrocodone, oxycodone, and methadone). Polymorphisms in CYP2D6 have been studied for an association with the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec025355c1679cbc2986e0e2e94990d
https://doi.org/10.1002/cpt.2149
https://doi.org/10.1002/cpt.2149
Autor:
Liza-Marie Johnson, Katianne M. Howard Sharp, Lynn W. Harrison, Leslie Taylor, Belinda N. Mandrell, Kayla V. Hamilton, Elsie L. Gerhardt, Mary V. Relling, Regina Nuccio, Anusha Sunkara, Cyrine E. Haidar, Michelle Pritchard, Jami S. Gattuso, Chimene Kesserwan, Emily Quinn, Rose B. McGee, Annastasia A. Ouma, Guolian Kang, Kim E. Nichols, Niki Jurbergs, Stacy Hines-Dowell
Publikováno v:
JCO Precis Oncol
PURPOSEFor the advances of pediatric oncology next-generation sequencing (NGS) research to equitably benefit all children, a diverse and representative sample of participants is needed. However, little is known about demographic and clinical characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05b2e820acddf860e04b33f69f0945c
https://doi.org/10.1200/po.19.00213
https://doi.org/10.1200/po.19.00213
Autor:
Elizabeth R. Sniderman, Dylan E. Graetz, Asya Agulnik, Radhikesh Ranadive, Yuvanesh Vedaraju, Yichen Chen, Meenakshi Devidas, Guillermo L. Chantada, Laila Hessissen, Rashmi Dalvi, Kathy Pritchard‐Jones, Carlos Rodriguez‐Galindo, Daniel C. Moreira, Nancy S. Bolous, Cyrine E. Haidar, Laure Bihannic, Diana Sa da Bandeira, Jade Xiaoqing Wang, Dongfang Li, Flavia Graca, Aksana Vasilyeva, Harry Lesmana
Publikováno v:
Cancer. 128(7)
Coronavirus disease 2019 (COVID-19) disrupted pediatric oncology care globally, increasing demands on health care providers (HCPs) who adapted to continue care. This study sought to characterize the pandemic's impact on pediatric oncology HCPs worldw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea7ba472304afae109d575c156ddf05
https://pubmed.ncbi.nlm.nih.gov/35067925
https://pubmed.ncbi.nlm.nih.gov/35067925