Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Cyrille Orset"'
Autor:
Daniel Bormann, Michael Knoflach, Emilia Poreba, Christian J. Riedl, Giulia Testa, Cyrille Orset, Anthony Levilly, Andréa Cottereau, Philipp Jauk, Simon Hametner, Nadine Stranzl, Bahar Golabi, Dragan Copic, Katharina Klas, Martin Direder, Hannes Kühtreiber, Melanie Salek, Stephanie zur Nedden, Gabriele Baier-Bitterlich, Stefan Kiechl, Carmen Haider, Verena Endmayr, Romana Höftberger, Hendrik J. Ankersmit, Michael Mildner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Neuroglia critically shape the brain´s response to ischemic stroke. However, their phenotypic heterogeneity impedes a holistic understanding of the cellular composition of the early ischemic lesion. Here we present a single cell resolution
Externí odkaz:
https://doaj.org/article/fb00e8b02b67459685bfb29a2e9fa2ce
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Early diagnosis is a critical part of the emergency care of cerebral hemorrhages and ischemia. A rapid and accurate diagnosis of strokes reduces the delays to appropriate treatments and a better functional recovery. Currently, CTscan and MRI
Externí odkaz:
https://doaj.org/article/59960e99a95443d28ee7bf9e42c07b23
Autor:
Héloïse Lebas, Alexandre Boutigny, Clémence Maupu, Jonas Salfati, Cyrille Orset, Mikael Mazighi, Philippe Bonnin, Yacine Boulaftali
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 2 (2023)
Background During the past few decades, several pathophysiological processes contributing to intracranial aneurysm (IA) rupture have been identified, including irregular IA shape, altered hemodynamic stress within the IA, and vessel wall inflammation
Externí odkaz:
https://doaj.org/article/985c077590a940f7bee93165c7aca8d6
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract In acute ischemic stroke, the only FDA-approved drug; recombinant tissue plasminogen activator (rt-PA) is limited by restricted time-window due to an enhanced risk of hemorrhagic transformation which is thought to be caused by metalloprotein
Externí odkaz:
https://doaj.org/article/49c1907db9404eb5a063005ab022e9b9
Autor:
LeeAnn Ramsay, Marie‐Lise Quillé, Cyrille Orset, Pierre de laGrange, Estelle Rousselet, Claude Férec, Gérald Le Gac, Emmanuelle Génin, Serge Timsit
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 9, Pp 1681-1695 (2019)
Abstract Objectives Blood biomarkers for cerebral tissue ischemia are lacking. The goal was to identify a blood transcriptomic signature jointly identified in the ischemic brain. Methods A nonhuman primate model with middle cerebral artery (MCA) terr
Externí odkaz:
https://doaj.org/article/c6cf0ce2bb62404e9a0a42db45ae0385
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/04d1273dc473490aa5a1afab1cf4feeb
Autor:
Sabine François, Stanislas Mondot, Quentin Gerard, Rosalie Bel, Julie Knoertzer, Asma Berriche, Sophie Cavallero, Rachid Baati, Cyrille Orset, Gregory Dal Bo, Karine Thibault
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1167 (2022)
Anxiety disorder is one of the most reported complications following organophosphorus (OP) nerve agent (NA) exposure. The goal of this study was to characterize the long-term behavioral impact of a single low dose exposure to 4-nitrophenyl isopropyl
Externí odkaz:
https://doaj.org/article/fe6a20bca88f4ebeb691f36446f45b67
Autor:
Nadine Felizitas Binder, Mohamad El Amki, Chaim Glück, William Middleham, Anna Maria Reuss, Adrien Bertolo, Patrick Thurner, Thomas Deffieux, Hannah-Lea Handelsmann, Philipp Baumgartner, Cyrille Orset, Philipp Bethge, Zsolt Kulcsar, Adriano Aguzzi, Mickael Tanter, Denis Vivien, Matthias T. Wyss, Andreas Luft, Michael Weller, Bruno Weber, Susanne Wegener
Recanalization is the mainstay of ischemic stroke treatment. However, even with timely clot removal, many stroke patients recover poorly. Leptomeningeal collaterals (LMCs) are pial anastomotic vessels with yet unknown functions. Utilizing a thrombin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0d27bbd41e203c030ab20079552ec71
https://doi.org/10.1101/2023.02.25.529915
https://doi.org/10.1101/2023.02.25.529915
Autor:
Nane Griem-Krey, Anders B Klein, Bettina H Clausen, Mathias RJ Namini, Pernille V Nielsen, Mozammel Bhuiyan, Raghavendra Y Nagaraja, T Michael De Silva, Christopher G Sobey, Heung-Chin Cheng, Cyrille Orset, Denis Vivien, Kate L Lambertsen, Andrew N Clarkson, Petrine Wellendorph
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. :0271678X2311679
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a major contributor to physiological and pathological glutamate-mediated Ca2+ signals, and its involvement in various critical cellular pathways demands specific pharmacological strategi
Autor:
Victor Llombart, Anna Penalba, Leire Azurmendi, Cyrille Orset, Marc Ribo, Alba Simats, Oriol Ventura, Emili Pecharroman, Denis Vivien, Joan Montaner, Alejandro Bustamante, Jean-Charles Sanchez
Publikováno v:
Neurology. 96:e1928-e1939
ObjectiveTo validate a panel of blood biomarkers to differentiate between ischemic stroke (IS) and intracerebral hemorrhage (ICH) in patients with suspected stroke.MethodsPatients with suspected stroke admitted within 4.5 hours after onset were enrol