Výsledky vyhledávání - "Cyrille Amegashie"

Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers

Autor: Chris Focht, Gregory A. Deye, Cyrille Amegashie, Evan J. Anderson, Allison Beck, Terry L. Bowlin, Nadine Rouphael, Selwyn J. Hurwitz, Blaire L. Osborn, Shu Yi Cai, Mari Hart, Mark J. Mulligan, Jennifer Brooks

Publikováno v: Antimicrobial agents and chemotherapy. 63(9)

Filociclovir (MBX-400, cyclopropavir) is an antiviral agent with activity against cytomegalovirus (CMV). A phase 1, double-blind, randomized, placebo-controlled (3:1 ratio), single-center, multiple-ascending-dose trial was conducted to assess the saf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd7dcf9992ee2a5f03954ec0483fb61
https://pubmed.ncbi.nlm.nih.gov/31285228

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Safety and efficacy of a cytomegalovirus glycoprotein B (gB) vaccine in adolescent girls: A randomized clinical trial

Autor: Lawrence R. Stanberry, Sylvie Pichon, Richard E. Rupp, Flor M. Munoz, Susan H. Wootton, Shital M. Patel, Cyrille Amegashie, S. Todd Callahan, Christine B. Turley, Kathryn M. Edwards, David I. Bernstein, Monica M. McNeal, Abbie R. Bellamy

Publikováno v: Vaccine. 34:313-319

Cytomegalovirus (CMV) is a leading cause of congenital infection and an important target for vaccine development.CMV seronegative girls between 12 and 17 years of age received CMV glycoprotein B (gB) vaccine with MF59 or saline placebo at 0, 1 and 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d603c905e1183f5a09d46b89027a0d
https://doi.org/10.1016/j.vaccine.2015.11.056

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A randomized, placebo-controlled phase I trial of live, attenuated herpes zoster vaccine in subjects with end-stage renal disease immunized prior to renal transplantation

Autor: Cyrille Amegashie, Geraldine G. Miller, Heidi M. Schaefer, Michael R. Wierzbicki, Rachel Miller, Patricia L. Winokur, David K. Klassen, Karen L. Kotloff, Kathryn M. Edwards, Sandra M. Yoder

Publikováno v: Transplant Infectious Disease. 20:e12874

Background Solid organ transplant recipients are at increased risk for reactivation of herpes zoster, or shingles, and have a higher frequency of serious complications including post-herpetic neuralgia. A live, attenuated shingles vaccine is effectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d58de70b75849190c6827868f04f76
https://doi.org/10.1111/tid.12874

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