Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Cyril Privezentzev"'
Autor:
Matthew A. Sleeman, Jayne Hammersley, Rose Marwood, Vikki Knights, Cyril Privezentzev, Trevor Wilkinson, Catherine Huntington, Jonathan Seaman, Tristan J. Vaughan, David Rider, David C. Lowe, Donna K. Finch, Margareta Ek, Tove Sjögren, Peter Cariuk, Jonna K Hakulinen, Julie A. Douthwaite, Joyce Young, Sudharsan Sridharan
Publikováno v:
mAbs
'mAbs ', vol: 7, pages: 152-166 (2015)
'mAbs ', vol: 7, pages: 152-166 (2015)
Therapeutic monoclonal antibodies targeting G-protein-coupled receptors (GPCRs) are desirable for intervention in a wide range of disease processes. The discovery of such antibodies is challenging due to a lack of stability of many GPCRs as purified
Autor:
Julie Douthwaite, Jacques Moisan, Cyril Privezentzev, Blagoje Soskic, Shereen Sabbah, Suzanne Cohen, Andie Collinson, Elizabeth England, Catherine Huntington, Ben Kemp, Li Zhuang, Suzanne Hudak, D. Gareth Rees, Debbie Goldberg, Chris Barton, Linda Chang, Inna Vainshtein, Meina Liang, Laurie Iciek, Philip Ambery, Mark Peakman, Tristan J. Vaughan, Tim I. M. Tree, David M. Sansom, Michael A. Bowen, Ralph R. Minter, Lutz Jermutus
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(5)
Autor:
Tristan J. Vaughan, Linda Chang, Laurie Iciek, Timothy Tree, Philip Ambery, Elizabeth England, Inna Vainshtein, Debbie Goldberg, Catherine Huntington, Meina Liang, Suzanne Hudak, Suzanne Cohen, Chris Barton, Mark Peakman, Julie A. Douthwaite, Ben Kemp, Blagoje Soskic, Jacques Moisan, Li Zhuang, Ralph Minter, D. Gareth Rees, Andie Collinson, Shereen Sabbah, Michael A. Bowen, Lutz Jermutus, David M. Sansom, Cyril Privezentzev
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(1)
Affinity- and stability-engineered variants of CTLA4-Ig fusion molecules with enhanced pharmacokinetic profiles could yield improved therapies with the potential of higher efficacy and greater convenience to patients. In this study, to our knowledge,