Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Cyril Neftel"'
Autor:
Iris Oezen, Michael Kilian, Michael O. Breckwoldt, Mario L. Suvà, Michael C. Burger, Mirco Friedrich, Khwab Sanghvi, Karl H. Plate, Magdalena Kramer, Sevin Turcan, Daniel Hänggi, Niklas Thon, Daniel Schrimpf, Stefan Kaulfuss, Katrin Deumelandt, Jochen Meyer, Richard Harbottle, Jürgen G. Okun, Theresa Bunse, Edward W. Green, Tobias Kessler, Miriam Ratliff, Michael Platten, Jana K. Sonner, Brandon Nicolay, Marion Dorsch, Michael Weller, Anna von Landenberg, Ruslan Al-Ali, Mya Steadman, Matthias Bozza, Holger Hess-Stumpp, Karen Bieback, Dongwei Zhu, Stefan Pusch, Cyril Neftel, Wolfgang Wick, Jessica Eisel, Benedikt Wiestler, Antje Habel, Minou Nadji-Ohl, Axel Benner, Christel Herold-Mende, Anna S. Berghoff, Dalia Alansary, Patrick N. Harter, Lukas Bunse, Kelly Marsh, Gernot Poschet, Barbara A. Niemeyer, Andreas von Deimling, Daniel P. Cahill, Felix Sahm, Simone Karcher-Bausch, Matthias Preusser, Stefanie Uhlig
Publikováno v:
Nature Medicine. 24:1192-1203
The oncometabolite (R)-2-hydroxyglutarate (R-2-HG) produced by isocitrate dehydrogenase (IDH) mutations promotes gliomagenesis via DNA and histone methylation. Here, we identify an additional activity of R-2-HG: tumor cell-derived R-2-HG is taken up
Autor:
Mario L. Suvà, Christine Hebert, Iain A. Drummond, Martin J. Aryee, Luca Pinello, McKenzie Shaw, Caleb A. Lareau, John C. Moore, Riadh Lobbardi, Cyril Neftel, Sowmya Iyer, Andre Bernards, David M. Langenau, Craig J. Ceol, Huidong Chen, Qin Tang
Publikováno v:
The Journal of Experimental Medicine
The work by Tang et al. provides a comprehensive, single-cell, transcriptomic analysis of kidney and blood cells from the adult zebrafish, identifying novel cell types, including two classes of NK immune cells, classically defined and erythroid-prime
Autor:
Nikhil Wagle, Peter K. Sorger, Angela Volorio, Christophe H. Georgescu, Nicolo Riggi, Liliane C. Broye, Lan Nguyen, Ivan Chebib, Brian J. Haas, Nathan Mathewson, Johannes C. Melms, Marni E. Shore, Orit Rozenblatt-Rosen, Joseph M. Beechem, Cyril Neftel, Kai W. Wucherpfennig, Ofir Cohen, Jorge E. Buendia-Buendia, Michael Montemurro, Luisa Cironi, Shaolin Mei, Alyssa R. Richman, Igor Letovanec, Miguel Rivera, Mario L. Suvà, Michael S. Cuoco, Hannah R. Weisman, G. Petur Nielsen, Alex B. Haynes, Livnat Jerby-Arnon, Asa Segerstolpe, Cigall Kadoch, Christina C. Luo, John T. Mullen, Gaylor Boulay, Matthew J. McBride, Gregory M. Cote, Aviv Regev, Ravindra Mylvaganam, Benjamin Izar, Stéphane Cherix, Nicole Ortogero, Simon Gritsch, Danny Labes, Ivan Stamenkovic, Malika Sud, Tu Nguyen-Ngoc, Daniel R. Zollinger, Edwin Choy, Joseph M. Gurski
Publikováno v:
Nat Med
Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18–SSX fusion, and is characterized by low T cell infiltration. Here, we studied the cancer–immune interplay in SyS using an integrative approach that combines single-cell RNA seque
Autor:
Joseph M. Beechem, Zollinger, Ivan Stamenkovic, Alyssa R. Richman, Christophe H. Georgescu, Angela Volorio, Peter K. Sorger, Joseph M. Gurski, Cyril Neftel, HR Weissman, Cuoco, Igor Letovanec, Gaylor Boulay, Nikhil Wagle, Orit Rozenblatt-Rosen, Danny Labes, Mario-Luca Suvà, Edwin Choy, Ivan Chebib, Ben Izar, Miguel Rivera, Christina C. Luo, Matthew J. McBride, Gregory M. Cote, Luisa Cironi, Brian J. Haas, Ofir Cohen, Shaolin Mei, Marni E. Shore, Jorge E. Buendia-Buendia, Aviv Regev, Nicolo Riggi, Livnat Jerby-Arnon, Stéphane Cherix, Cigall Kadoch, Ravindra Mylvaganam, John T. Mullen, Liliane C. Broye, Alex B. Haynes, Jc Melms, Gunnlaugur P. Nielsen, Lan T. Nguyen
Synovial sarcoma is an aggressive mesenchymal neoplasm, driven by the SS18-SSX fusion, and characterized by immunogenic antigens expression and exceptionally low T cell infiltration levels. To study the cancer-immune interplay in this disease, we pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15d6fa81c4c5eeaa50d0c025cdff1e6
Autor:
Daniel P. Cahill, Tracy T. Batchelor, Priscilla K. Brastianos, William T. Curry, Orit Rozenblatt-Rosen, Dennis M. Bonal, John M. DeWitt, Ivan Stamenkovic, Anoop P. Patel, Inder M. Verma, Irene Slavc, Aviv Regev, Ravindra Mylvaganam, René Geyeregger, Mario L. Suvà, Christine M. Hebert, Anat Stemmer-Rachamimov, Julia L. Small, Lisa Mayr, Nicholas Druck, Alexander Kaplan, Simon Gritsch, Sarah Becker, L. Nicolas Gonzalez Castro, David N. Louis, Toshiro Hara, Danielle Dionne, Brian V. Nahed, Rachel L. Servis, Xiaoyang Lan, McKenzie Shaw, Keith L. Ligon, Cyril Neftel, Christopher Rodman, Kristine Pelton, Johannes Gojo, Mariella G. Filbin, Matthew P. Frosch, Esther Rheinbay, Tony Hunter, Michelle Monje, Marni E. Shore, Dana Silverbush, Elizabeth M. Perez, Gilbert J. Rahme, Hiroaki Wakimoto, Jeremy M. Fung, Quang-Dé Nguyen, Itay Tirosh, Maria Martinez-Lage, Julie Laffy, Alyssa R. Richman, Mia Bertalan, Thomas Czech, Christine Haberler, Bradley E. Bernstein, Nicolo Riggi, Bob S. Carter
Publikováno v:
Cell
PMC
PMC
Diverse genetic, epigenetic, and developmental programs drive glioblastoma, an incurable and poorly understood tumor, but their precise characterization remains challenging. Here, we use an integrative approach spanning single-cell RNA-sequencing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85367a06752131d82809bde947d45b2f
https://europepmc.org/articles/PMC6703186/
https://europepmc.org/articles/PMC6703186/
Autor:
Cyril Neftel, Tracy T. Batchelor, Angel M. Carcaboso, Gerhard Fritsch, Pratiti Bandopadhayay, Andreas Peyrl, Claire Sinai, Mara Popović, Quang-Dé Nguyen, Orit Rozenblatt-Rosen, Christina C. Luo, Itay Tirosh, Michelle Monje, Kai W. Wucherpfennig, Alexander M. Beck, Peter van Galen, Dennis M. Bonal, Gad Getz, Christian Dorfer, Volker Hovestadt, Nathan Mathewson, Mariella G. Filbin, Mark W. Kieran, Kristine Pelton, Keren Yizhak, Rameen Beroukhim, Maria Martinez-Lage, Ravindra Mylvaganam, Kristof Egervari, Christine Haberler, Jaume Mora, Keith L. Ligon, Johannes Gojo, McKenzie Shaw, Christine M. Hebert, Nelli Frank, Bradley E. Bernstein, Todd R. Golub, Christopher Mount, Matthew P. Frosch, Cinzia Lavarino, Thomas Czech, Amedeo A. Azizi, Mario L. Suvà, David N. Louis, Aviv Regev, Liliana Goumnerova, Irene Slavc, Leah E. Escalante
Publikováno v:
Science
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
The cellular composition of H3K27M gliomas Diffuse midline gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-glioma) are an aggressive type of childhood cancer with few options for treatment. Filbin et al. used a single-cell sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488c4f260a177a7c8e9b5eb440e8f8ef
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14257
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14257
Autor:
McKenzie Shaw, Christopher Mount, Miguel Rivera, Priscilla K. Brastianos, William T. Curry, Todd R. Golub, Matthew P. Frosch, Christina C. Luo, Ravindra Mylvaganam, Orit Rozenblatt-Rosen, Daniel P. Cahill, Danielle Dionne, Volker Hovestadt, Shawn M. Gillespie, Keren Yizhak, Hiroaki Wakimoto, Maristela L. Onozato, Christopher Rodman, Anoop P. Patel, Andrew S. Venteicher, Bradley E. Bernstein, Gad Getz, Mariella G. Filbin, Brian V. Nahed, Christine Hebert, Michelle Monje, A. John Iafrate, David N. Louis, Itay Tirosh, Cyril Neftel, Aviv Regev, Mario L. Suvà, Hiranmayi Ravichandran, Leah E. Escalante
Publikováno v:
Science, vol. 355, no. 6332, pp. 1391
PMC
PMC
Tumor subclasses differ according to the genotypes and phenotypes of malignant cells as well as the composition of the tumor microenvironment (TME).We dissected these influences in isocitrate dehydrogenase (IDH)-mutant gliomas by combining 14,226 sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7d666055f7b5926de64370899646af
https://serval.unil.ch/resource/serval:BIB_0420876AC9F2.P002/REF.pdf
https://serval.unil.ch/resource/serval:BIB_0420876AC9F2.P002/REF.pdf
Autor:
Rahul Satija, Jackson Nyman, Itay Tirosh, Gad Getz, Mariella G. Filbin, David Gennert, Todd R. Golub, Leah E. Escalante, Keren Yizhak, Nicolo Riggi, Benjamin Izar, Christopher Rodman, Robert L. Martuza, Mario L. Suvà, Andrew S. Venteicher, Orit Rozenblatt-Rosen, Maristela L. Onozato, Christopher Mount, Jonathan M. Fisher, Bradley E. Bernstein, William T. Curry, Joshua M. Francis, Christina C. Luo, Matthew P. Frosch, Cyril Neftel, Niyati Desai, Michelle Monje, A. John Iafrate, Aanand A. Patel, Anoop P. Patel, Aviv Regev, Daniel P. Cahill, Kenneth J. Livak, Miguel Rivera, Ravindra Mylvaganam, Christine Hebert, David N. Louis, Brian V. Nahed
Publikováno v:
PMC
Although human tumours are shaped by the genetic evolution of cancer cells, evidence also suggests that they display hierarchies related to developmental pathways and epigenetic programs in which cancer stem cells (CSCs) can drive tumour growth and g
Autor:
Volker Hovestadt, Itay Tirosh, Pratiti Bandopadhayay, Daniel P. Cahill, Leah E. Escalante, Will Curry, Andrew S. Venteicher, David N. Louis, Mariella G. Filbin, Brian V. Nahed, Kristine Pelton, Aviv Regev, Liliana Goumnerova, Irene Slavc, Michelle Monje, Thomas Czech, Cyril Neftel, Keith L. Ligon, Todd R. Golub, Christine Hebert, McKenzie Shaw, Mario L. Suvà
Publikováno v:
Neuro-Oncology. 18:vi77-vi77
Publikováno v:
PrimaryCare. 13:51-52