Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Cyril Leven"'
Autor:
Cyril Leven, Pauline Ménard, Isabelle Gouin-Thibault, Alice Ballerie, Karine Lacut, Edouard Ollier, Jérémie Théreaux
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 665 (2023)
Apixaban and rivaroxaban have first-line use for many patients needing anticoagulation for venous thromboembolism (VTE). The pharmacokinetics of these drugs in non-obese subjects have been extensively studied, and, while changes in pharmacokinetics h
Externí odkaz:
https://doaj.org/article/01f83f47119549369478f547bcfa1775
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 442 (2022)
Model-informed precision dosing is being increasingly used to improve therapeutic drug monitoring. To meet this need, several tools have been developed, but open-source software remains uncommon. Posologyr is a free and open-source R package develope
Externí odkaz:
https://doaj.org/article/ef05eb611866403b9406b85c10fc8111
Autor:
Cyril Leven, Sacha Schutz, Marie-Pierre Audrezet, Emmanuel Nowak, Laurent Meijer, Tristan Montier
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1087 (2020)
Roscovitine (Seliciclib), a new protein kinase inhibitor, was administered orally to adult patients with cystic fibrosis for the first time in the ROSCO-CF trial, a dose-escalation, phase IIa, randomized, controlled trial. Extensive pharmacokinetic s
Externí odkaz:
https://doaj.org/article/8cb0c141079540e792e4ea85827d725c
Publikováno v:
Sages-Femmes. 21:45-49
Autor:
Ianis Cousin, Camille Basmaison, Elie Cousin, Nicolas Lebonvallet, Isabelle Germouty, Cyril Leven, Philine De Vries
Publikováno v:
Journal of pediatric urology. 18(5)
Proximal hypospadias surgery is impacted by a high complication rate. The goal of this work was to assess the overall composite complication rate, fistula rate and stenosis rate following proximal hypospadias surgery realized according to onlay ureth
Autor:
Olivier Huet, Claire Hoffmann, Jean-Luc Carré, Cecile Aubron, Éléonore Bettacchioli, Maël Padelli, Geneviève Héry-Arnaud, Véronique Vermeersch, Cyril Leven, Hadrien Maguet
Publikováno v:
Australian Critical Care. 34:47-54
Background Hypophosphataemia affects up to one-third of patients in the intensive care unit (ICU) and is particularly common during sepsis. Experimental data suggest that hypophosphataemia leads to an acquired dysfunction of leukocytes, thus promotin
Autor:
Charles Roche, Cyril Leven, Clément Hoffmann, Francis Couturaud, Jérémie Thereaux, Karine Lacut
Publikováno v:
Fundamental & Clinical Pharmacology. 35:53-61
The prevalence of obesity has been steadily increasing in recent years worldwide. At the same time bariatric surgery, the best therapeutic strategy to date in terms of sustainable weight loss and improvement of associated comorbidities has been also
Autor:
Laurent Misery, Emilie Brenaut, Claire Abasq-Thomas, Joachim W. Fluhr, Nicolas Lebonvallet, Christelle Le Gall-Ianotto, Ophélie Pierre, Catherine Besner-Morin, Matthieu Talagas, Olivier Gouin, Cyril Leven, Raphaele Le Garrec
Publikováno v:
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2021, ⟨10.1111/bph.15672⟩
British Journal of Pharmacology, Wiley, 2021, ⟨10.1111/bph.15672⟩
Until recently, itch pathophysiology was poorly understood and treatments were poorly effective in relieving itch. Current progress in our knowledge of the itch processing, the numerous mediators and receptors involved has led to a large variety of p
Autor:
Laurent Meijer, Geneviève Hery-Arnaud, Cyril Leven, Emmanuel Nowak, Sophie Hillion, Yves Renaudineau, Isabelle Durieu, Raphaël Chiron, Anne Prevotat, Isabelle Fajac, Dominique Hubert, Marlène Murris-Espin, Sandrine Huge, Isabelle Danner-Boucher, Bruno Ravoninjatovo, Sylvie Leroy, Julie Macey, Thierry Urban, Gilles Rault, Dominique Mottier, Rozenn Le Berre
Publikováno v:
Journal of Cystic Fibrosis
Journal of Cystic Fibrosis, 2022, 21 (3), pp.529-536. ⟨10.1016/j.jcf.2021.10.013⟩
Journal of Cystic Fibrosis, 2021, ⟨10.1016/j.jcf.2021.10.013⟩
Journal of Cystic Fibrosis, 2022, 21 (3), pp.529-536. ⟨10.1016/j.jcf.2021.10.013⟩
Journal of Cystic Fibrosis, 2021, ⟨10.1016/j.jcf.2021.10.013⟩
International audience; Background: The orally available kinase inhibitor R-roscovitine has undergone clinical trials against various cancers and is currently under clinical evaluation against Cushing disease and rheumatoid arthritis. Roscovitine dis
Autor:
Maël Padelli, Jean-Luc Carré, Juliette Chauvet, Christelle Boglione-Kerrien, Cyril Leven, Jean-Baptiste Foulquier
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 57:e192-e195