Výsledky vyhledávání - "Cyril J. Smyth"

Mutagenesis of the Rns regulator of enterotoxigenic Escherichia coli reveals roles for a linker sequence and two helix–turn–helix motifs

Autor: Cyril J. Smyth, Stephen G. J. Smith, Vivienne Mahon

Publikováno v: Microbiology. 156:2796-2806

The pathogenesis of diarrhoeal disease due to human enterotoxigenic Escherichia coli absolutely requires the expression of fimbriae. The expression of CS1 fimbriae is positively regulated by the AraC-like protein Rns. AraC-like proteins are DNA-bindi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff8641ff27554bfffb89509060d69be
https://doi.org/10.1099/mic.0.038521-0

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Inhibition of Noradrenaline-Stimulated Lipolysis and Cyclic AMP Accumulation in Isolated Rat Adipocytes by Purified Phospholipase C and Theta-Toxin from Clostridium Perfringens

Autor: Bertil B. Fredholm, Torsten Malmquist, Per Anderson, Roland Möllby, Cyril J. Smyth

Publikováno v: Acta Pharmacologica et Toxicologica. 42:23-34

Purified phospholipase C (phosphatidylcholine cholinephosphohydrolase, EC 3.1.4.3) and thetatoxin from Clostridium perfringens both inhibited noradrenaline-stimulated lipolysis and cyclic AMP accumulation in isolated rat adipocytes in a dose-dependen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086ae35b50ade7381464d7fb729eb4cc
https://doi.org/10.1111/j.1600-0773.1978.tb02167.x

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Use of immunoprecipitates to obtain monospecific immunoglobulins to nuclease 1 of Tradescantia

Autor: David E. Clapham, Cyril J. Smyth

Publikováno v: Hereditas. 96:69-75

Progressively more specific immunoglobulins were raised in rabbits against nuclease 1 of Tradescantia paludosa, the final antiserum being monospecific. The original antiserum raised against the purified enzyme preparation gave rise to several immunop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::674fee419ab697edc897afb3480eb97b
https://doi.org/10.1111/j.1601-5223.1982.tb00035.x

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Pathogenomic Analysis of the Common BovineStaphylococcus aureusClone (ET3): Emergence of a Virulent Subtype with Potential Risk to Public Health

Autor: Daniel E. Sturdevant, Davida S. Smyth, Michael Otto, Cyril J. Smyth, Vivek Kapur, P.J. Hartigan, Lisa Herron-Olson, Caitriona M. Guinane, J. Ross Fitzgerald, Amer E. Villaruz

Publikováno v: Guinane, C.M., Sturdevant, D.E., Herron-Olson, L., Otto, M., Smyth, D.S., Villaruz, A.E., Kapur, V., Hartigan, P.J., Smyth, C.J., Fitzgerald, J.R., Pathogenomic analysis of the common bovine Staphylococcus aureus clone (ET3): emergence of a virulent subtype with potential risk to public health, The Journal of Infectious Diseases, 197, 2008, 205, 213

A common clone (ET3) of Staphylococcus aureus is responsible for a large proportion of cases of bovine mastitis and occasionally causes zoonotic infections of humans. In the present study, we report the identification of a virulent clonal subtype (ST

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6e8f6c1cd71150003bdde29bb767c0
https://doi.org/10.1086/524689

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Occurrence of ssl genes in isolates of Staphylococcus aureus from animal infection

Autor: Davida S. Smyth, P.J. Hartigan, William J. Meaney, Cyril J. Smyth

Publikováno v: Journal of Medical Microbiology. 56:418-425

The occurrence of 7 of the 11 known ssl genes that are found within the vSaalpha genomic island of Staphylococcus aureus and encode the novel Ssl family of exoproteins was examined in isolates from cows (42 isolates), goats (4 isolates), sheep (1 iso

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https://doi.org/10.1099/jmm.0.46878-0

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Fine-Structure Molecular Typing of Irish Helicobacter pylori Isolates and Their Genetic Relatedness to Strains from Four Different Continents

Autor: Niyaz Ahmed, Sarah M. Beesley, Ian M. Carroll, Cyril J. Smyth, Colm A. Ó. Moráin, Aleem Ahmed Khan, Sheikh Ghousunnissa

Publikováno v: Journal of Clinical Microbiology. 41:5755-5759

Genotyping of 74 Irish Helicobacter pylori isolates was performed at four different loci ( vacA signal sequence and mid-region, insertion-deletion polymorphisms at the 3′ end of the cag pathogenicity island, and cagA ). The predominant vacA alleles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ecd730c0ad8824b370a2d2c008fdf6
https://doi.org/10.1128/jcm.41.12.5755-5759.2003

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Characterization of a Putative Pathogenicity Island from Bovine Staphylococcus aureus Encoding Multiple Superantigens

Autor: Cyril J. Smyth, P.J. Hartigan, Gregory A. Bohach, Steven R. Monday, J. Ross Fitzgerald, William J. Meaney, Timothy J. Foster

Publikováno v: Journal of Bacteriology. 183:63-70

Previous studies have demonstrated that a proportion of Staphylococcus aureus isolates from bovine mastitis coproduce toxic shock syndrome toxin (TSST) and staphylococcal enterotoxin C (SEC). In this study, molecular genetic analysis of one such stra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec018667391ec818dd8e099ba0f77694
https://doi.org/10.1128/jb.183.1.63-70.2001

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Population characteristics of IrishHelicobacter pylori isolates: a tRNA-associated locus

Autor: David G. Marshall, Cyril J. Smyth, William G. Dundon, C. A. Ó’Moráin

Publikováno v: Irish Journal of Medical Science. 169:137-140

A strain-variable transfer RNA-associated-locus (trl) was present in 50% of Irish Helicobacter pylori (H. pylori), isolates and did not correlate with the origin of the isolates.To associate a particular genotype or phenotype to trl status in H. pylo

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https://doi.org/10.1007/bf03166919

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A novel tRNA-associated locus (trl) from Helicobacter pylori is co-transcribed with tRNAGly and reveals genetic diversity

Autor: William G. Dundon, Colm A. Ó. Moráin, David G. Marshall, Cyril J. Smyth

Publikováno v: Microbiology. 145:1289-1298

To date several genes have been identified in Helicobacter pylori that are expressed in only a proportion of strains, some of which are correlated with the pathogenicity of the bacterium. With this in mind, the present study was undertaken to identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bce87b17cf1143d7dae2ac540d6a71f
https://doi.org/10.1099/13500872-145-6-1289

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