Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Cyril Denby-Wilkes"'
Autor:
Leo Zeitler, Kévin André, Adriana Alberti, Cyril Denby Wilkes, Julie Soutourina, Arach Goldar
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011799 (2024)
In eukaryotic cells, the one-dimensional DNA molecules need to be tightly packaged into the spatially constraining nucleus. Folding is achieved on its lowest level by wrapping the DNA around nucleosomes. Their arrangement regulates other nuclear proc
Externí odkaz:
https://doaj.org/article/f7ec2bc0d5904c12a5f3d351f9288754
Autor:
Kévin M. André, Nathalie Giordanengo Aiach, Veronica Martinez-Fernandez, Leo Zeitler, Adriana Alberti, Arach Goldar, Michel Werner, Cyril Denby Wilkes, Julie Soutourina
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112465- (2023)
Summary: Chromatin organization is crucial for transcriptional regulation in eukaryotes. Mediator is an essential and conserved co-activator thought to act in concert with chromatin regulators. However, it remains largely unknown how their functions
Externí odkaz:
https://doaj.org/article/f9bbea9526e54585825f206e6c20bd6d
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 9, p e1010488 (2022)
The great advances of sequencing technologies allow the in vivo measurement of nuclear processes-such as DNA repair after UV exposure-over entire cell populations. However, data sets usually contain only a few samples over several hours, missing poss
Externí odkaz:
https://doaj.org/article/8d1831405b1d41e389648e0a1362b0ec
Autor:
Frédéric Guérin, Olivier Arnaiz, Nicole Boggetto, Cyril Denby Wilkes, Eric Meyer, Linda Sperling, Sandra Duharcourt
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background DNA elimination is developmentally programmed in a wide variety of eukaryotes, including unicellular ciliates, and leads to the generation of distinct germline and somatic genomes. The ciliate Paramecium tetraurelia harbors two ty
Externí odkaz:
https://doaj.org/article/20624ba6fe6a449fae4f28084a2394d8
Autor:
Julien Bischerour, Simran Bhullar, Cyril Denby Wilkes, Vinciane Régnier, Nathalie Mathy, Emeline Dubois, Aditi Singh, Estienne Swart, Olivier Arnaiz, Linda Sperling, Mariusz Nowacki, Mireille Bétermier
Publikováno v:
eLife, Vol 7 (2018)
The domestication of transposable elements has repeatedly occurred during evolution and domesticated transposases have often been implicated in programmed genome rearrangements, as remarkably illustrated in ciliates. In Paramecium, PiggyMac (Pgm), a
Externí odkaz:
https://doaj.org/article/b92d5bf9a11e454582d088cafcb4da74
Autor:
Kévin M. André, Nathalie Giordanengo Aiach, Veronica Martinez-Fernandez, Leo Zeitler, Arach Goldar, Michel Werner, Cyril Denby Wilkes, Julie Soutourina
SummaryChromatin organization is crucial for the transcriptional regulation in eukaryotes. Mediator is an essential and conserved coactivator thought to act in concert with chromatin regulators. However, it remains largely unknown how their functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0e463fe484e5aafb78a4bf2704f3793
https://doi.org/10.1101/2022.09.22.509083
https://doi.org/10.1101/2022.09.22.509083
Autor:
Julie Soutourina, Florent Malloggi, Eliet H. Sipos, Adélaïde Léty-Stefanska, Cyril Denby Wilkes
Publikováno v:
Lab on a Chip. 21:2407-2416
Mutations in DNA have large-ranging consequences, from evolution to disease. Many mechanisms contribute to mutational processes such as dysfunctions in DNA repair pathways and exogenous or endogenous mutagen exposures. Model organisms and mutation ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::881925c4a351860c0b57be5a6eccfb74
https://doi.org/10.1039/d1lc00086a
https://doi.org/10.1039/d1lc00086a
Autor:
Diyavarshini Gopaul, Cyril Denby Wilkes, Arach Goldar, Nathalie Giordanengo Aiach, Marie-Bénédicte Barrault, Elizaveta Novikova, Julie Soutourina
Publikováno v:
Genome research.
Mediator is a conserved coregulator playing a key role in RNA polymerase (Pol) II transcription. Mediator also links transcription and nucleotide excision repair (NER) via a direct contact with Rad2/ERCC5(XPG) endonuclease. In this work, we analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b76993879cf92aafaddd1d3f26b008f
https://pubmed.ncbi.nlm.nih.gov/35738899
https://pubmed.ncbi.nlm.nih.gov/35738899
Autor:
Arach Goldar, Marie-Bénédicte Barrault, Julie Soutourina, Elizaveta A. Novikova, Diyavarshini Gopaul, Cyril Denby Wilkes, Nathalie Giordanengo Aiach
Transcription is coupled with DNA repair, especially within nucleotide excision repair (NER). Mediator is a conserved coregulator playing a key role in RNA polymerase (Pol) II transcription. Mediator also links transcription and NER via a direct cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb4f62da16d2a0f391d58257b19ed865
https://doi.org/10.1101/2021.10.20.465181
https://doi.org/10.1101/2021.10.20.465181
Autor:
Kamila Maliszewska-Olejniczak, Julita Gruchota, Robert Gromadka, Cyril Denby Wilkes, Olivier Arnaiz, Nathalie Mathy, Sandra Duharcourt, Mireille Bétermier, Jacek K Nowak
Publikováno v:
PLoS Genetics, Vol 11, Iss 7, p e1005383 (2015)
Because of their nuclear dimorphism, ciliates provide a unique opportunity to study the role of non-coding RNAs (ncRNAs) in the communication between germline and somatic lineages. In these unicellular eukaryotes, a new somatic nucleus develops at ea
Externí odkaz:
https://doaj.org/article/070aad39a73f4fd89b18ba0fab0e1ca2