Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cyril Boucher"'
Autor:
Antu K. Dey, Angela Lim, Jessica P. Dawson, Adin Ross-Gillespie, Mara Rossi, Mirva Hejjaoui Simoneau, Cyril Boucher, Wolf Palinsky, Mark B. Feinberg, Joseph G. Jardine, Bernhard Valldorf, Hervé Broly, Dennis R. Burton, Thomas Hassell, Philippe Dupraz, Rita Agostinetto, Devin Sok
Publikováno v:
Biotechnology and Bioengineering
Therapeutic proteins, including monoclonal antibodies, are typically manufactured using clonally‐derived, stable host cell lines, since consistent and predictable cell culture performance is highly desirable. However, selecting and preparing banks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51009b838b0fa98ca7b9d372a4dbd04a
https://pubmed.ncbi.nlm.nih.gov/34796474
https://pubmed.ncbi.nlm.nih.gov/34796474
Autor:
Rita Agostinetto, Jessica Dawson, Angela Lim, Mirva Hejjaoui-simoneau, Cyril Boucher, Bernhard Valldorf, Adin Ross-gillespie, Joseph Jardine, Devin Sok, Dennis Burton, Thomas Hassell, Hervé Broly, Wolf Palinsky, Philippe Dupraz, Mark Feinberg, Antu Dey
Therapeutic proteins, including monoclonal antibodies, are typically manufactured using clonally-derived, stable host cell lines, since consistent and predictable cell culture performance is highly desirable. However, selecting and preparing banks of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66208bd81826345146315939eff017c4
https://doi.org/10.22541/au.163251349.96835693/v1
https://doi.org/10.22541/au.163251349.96835693/v1
Publikováno v:
Cellular and Molecular Bioengineering. 1:204-215
Within the last three decades, surface plasmon resonance (SPR)-based optical biosensors have emerged as leading instruments for the study of biomolecular interactions. The rapid dissemination of the technology has provided researchers with versatile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::073f8c99c25e6e6135eda178f5335b9c
https://doi.org/10.1007/s12195-008-0035-5
https://doi.org/10.1007/s12195-008-0035-5
Autor:
Mario Jolicoeur, Antoine Demolliens, Cyril Boucher, Gregory De Crescenzo, Michael D. Buschmann, Yves Durocher
Publikováno v:
Bioconjugate Chemistry. 19:1849-1854
Chitosan has been reported as a promising material for gene and drug delivery as well as for tissue engineering and regenerative medicine. We report here the conjugation of a de novo designed coil peptide (Kcoil) to chitosan ( M(n) = 200 kDa) to achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc6e3d7035da4954641099ed90504e9
https://doi.org/10.1021/bc800066b
https://doi.org/10.1021/bc800066b
Autor:
Benoît Liberelle, Jingkui Chen, Gregory De Crescenzo, Yves Durocher, Mario Jolicoeur, Cyril Boucher
Publikováno v:
Bioconjugate chemistry. 21(12)
In an effort to evaluate the impact of various epidermal growth factor (EGF) grafting strategies upon cell surface receptor activation and cell adhesion, we generated low-fouling surfaces by homogeneously grafting carboxymethylated dextran (CMD) on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705eaa176d0bd9d9ca26787c41e27878
https://pubmed.ncbi.nlm.nih.gov/21058714
https://pubmed.ncbi.nlm.nih.gov/21058714
Autor:
Mario Jolicoeur, Cyril Boucher, Laurence Bartholin, Yves Durocher, Abderrazzak Merzouki, Benoît Liberelle, Gregory De Crescenzo, Frederic Murschel
Publikováno v:
Journal of immunological methods. 362(1-2)
The de novo designed heterodimeric E/K coiled-coil system has been previously demonstrated to be an excellent capture/dimerization system applicable to various needs in both biotechnology and pharmaceutical fields. Those include controlled protein di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9149124f127be375c6b101ee4f805447
https://pubmed.ncbi.nlm.nih.gov/20869967
https://pubmed.ncbi.nlm.nih.gov/20869967
Autor:
Marc Thibault, Mario Jolicoeur, Cyril Boucher, Michael D. Buschmann, Gregory De Crescenzo, Yves Durocher, Michael R. Wertheimer, Juan-Carlos Ruiz
Publikováno v:
Biomaterials. 31(27)
The development of new strategies for protein immobilization to control cell adhesion, growth and differentiation is of prime interest in the field of tissue engineering. Here we propose a versatile approach based on the interaction between two de no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39216a244559ecc5b493b2ebdfb641c6
https://pubmed.ncbi.nlm.nih.gov/20579729
https://pubmed.ncbi.nlm.nih.gov/20579729
Publikováno v:
Analytical biochemistry. 399(1)
We propose an approach for the detection of proteins by Western blot that takes advantage of the high-affinity interaction occurring between two de novo designed peptides, the E and K coils. As a model system, K coil-tagged epidermal growth factor (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f8be3c324bdffdeb6b1d14a279735b
https://pubmed.ncbi.nlm.nih.gov/20005863
https://pubmed.ncbi.nlm.nih.gov/20005863
We have elaborated and validated a novel approach for the oriented tethering of proteins such as the epidermal growth factor (EGF) on aminated surfaces. The grafting reactions were optimized to generate a dense and homogeneous EGF layer. Impact of EG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f073c33ee8ad77369cd321c6ad3a46c
https://nrc-publications.canada.ca/eng/view/object/?id=25695f56-bcf0-4d5b-ab48-f60592a19e6c
https://nrc-publications.canada.ca/eng/view/object/?id=25695f56-bcf0-4d5b-ab48-f60592a19e6c
Autor:
Mario Jolicoeur, Gilles St-Laurent, Cyril Boucher, Martin Loignon, Gregory De Crescenzo, Yves Durocher
For tissue engineering applications, growth factor immobilization on cell culture scaffolds bears the potential to stimulate cell proliferation while minimizing costs associated to soluble growth factor supply. In order to evaluate the potential of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e979e861f2eef52e300be70f2be9297c
https://nrc-publications.canada.ca/eng/view/object/?id=ae5dcf6a-1aaf-48f8-883f-b054652ab960
https://nrc-publications.canada.ca/eng/view/object/?id=ae5dcf6a-1aaf-48f8-883f-b054652ab960