Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cyril, Robil"'
Autor:
Imelda Raczkiewicz, Céline Rivière, Peggy Bouquet, Lowiese Desmarets, Audrey Tarricone, Charline Camuzet, Nathan François, Gabriel Lefèvre, Fabiola Silva Angulo, Cyril Robil, François Trottein, Sevser Sahpaz, Jean Dubuisson, Sandrine Belouzard, Anne Goffard, Karin Séron
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionThe COVID-19 pandemic caused by the SARS-CoV-2 virus has underscored the urgent necessity for the development of antiviral compounds that can effectively target coronaviruses. In this study, we present the first evidence of the antiviral
Externí odkaz:
https://doaj.org/article/def200eeec564e8ba02ba919bc6e57e1
Autor:
Séverine Heumel, Vinícius de Rezende Rodovalho, Charlotte Urien, Florian Specque, Patrícia Brito Rodrigues, Cyril Robil, Lou Delval, Valentin Sencio, Amandine Descat, Lucie Deruyter, Stéphanie Ferreira, Marina Gomes Machado, Adeline Barthelemy, Fabiola Silva Angulo, Joel. T Haas, Jean François Goosens, Isabelle Wolowczuk, Corinne Grangette, Yves Rouillé, Ghjuvan Grimaud, Marie Lenski, Benjamin Hennart, Marco Aurélio Ramirez Vinolo, François Trottein
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTThe gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, we used high-resolution shotgun metagenomics and targeted metabolomic analysis to characterize influenza-associ
Externí odkaz:
https://doaj.org/article/618c08bdb540421fb74bab6041041e05
Autor:
Loïc Chollet, Séverine Heumel, Lucie Deruyter, Fabrice Bouilloux, Lou Delval, Véronique Robert, Marie-Hélène Gevaert, Muriel Pichavant, Valentin Sencio, Cyril Robil, Isabelle Wolowczuk, Harry Sokol, Sandrine Auger, Alexandre Douablin, Philippe Langella, Jean-Marc Chatel, Corinne Grangette, François Trottein
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The gut-lung axis is critical during viral respiratory infections such as influenza. Gut dysbiosis during infection translates into a massive drop of microbially produced short-chain fatty acids (SCFAs). Among them, butyrate is important during influ
Externí odkaz:
https://doaj.org/article/54c6484d3fd148d894b1ac794e1371e5
Autor:
Gemma Bogard, Johanna Barthelemy, Aline Hantute-Ghesquier, Valentin Sencio, Patricia Brito-Rodrigues, Karin Séron, Cyril Robil, Anne Flourens, Florence Pinet, Delphine Eberlé, François Trottein, Martine Duterque-Coquillaud, Isabelle Wolowczuk
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-16 (2023)
Abstract Coronavirus disease 2019 (COVID-19, caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)) is primarily a respiratory illness. However, various extrapulmonary manifestations have been reported in patients with severe forms o
Externí odkaz:
https://doaj.org/article/8031905ea98f468dbf1ce46702705206
Autor:
Florent Sauve, Sreekala Nampoothiri, Sophie A. Clarke, Daniela Fernandois, Caio Fernando Ferreira Coêlho, Julie Dewisme, Edouard G. Mills, Gaetan Ternier, Ludovica Cotellessa, Cristina Iglesias-Garcia, Helge Mueller-Fielitz, Thibaud Lebouvier, Romain Perbet, Vincent Florent, Marc Baroncini, Ariane Sharif, June Ereño-Orbea, Maria Mercado-Gómez, Asis Palazon, Virginie Mattot, Florence Pasquier, Sophie Catteau-Jonard, Maria Martinez-Chantar, Erik Hrabovszky, Mercé Jourdain, Dominique Deplanque, Annamaria Morelli, Giulia Guarnieri, Laurent Storme, Cyril Robil, François Trottein, Ruben Nogueiras, Markus Schwaninger, Pascal Pigny, Julien Poissy, Konstantina Chachlaki, Claude-Alain Maurage, Paolo Giacobini, Waljit Dhillo, S. Rasika, Vincent Prevot
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104784- (2023)
Summary: Background: We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during pathological aging, including Down syndrome and Alzheim
Externí odkaz:
https://doaj.org/article/805ae189cc654b398588ba98e00a06f8
Autor:
Valentin Sencio, Arnaud Machelart, Cyril Robil, Nicolas Benech, Eik Hoffmann, Chloé Galbert, Lucie Deryuter, Séverine Heumel, Aline Hantute-Ghesquier, Anne Flourens, Priscille Brodin, Fabrice Infanti, Virgile Richard, Jean Dubuisson, Corinne Grangette, Thierry Sulpice, Isabelle Wolowczuk, Florence Pinet, Vincent Prévot, Sandrine Belouzard, François Briand, Martine Duterque-Coquillaud, Harry Sokol, François Trottein
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral infections. We herein hypothesized that disruption of gut homeostasis during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may associat
Externí odkaz:
https://doaj.org/article/550d4d66dfae45ffb125630022a5aad4
Autor:
Valentin Sencio, Nicolas Benech, Cyril Robil, Lucie Deruyter, Séverine Heumel, Arnaud Machelart, Thierry Sulpice, Antonin Lamazière, Corinne Grangette, François Briand, Harry Sokol, François Trottein
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Obese patientss with nonalcoholic steatohepatitis (NASH) are particularly prone to developing severe forms of coronavirus disease 19 (COVID-19). The gut-to-lung axis is critical during viral infections of the respiratory tract, and a change in the gu
Externí odkaz:
https://doaj.org/article/a5f3a88364964b48ab00ce67879bbede
Autor:
Sandrine Belouzard, Arnaud Machelart, Valentin Sencio, Thibaut Vausselin, Eik Hoffmann, Nathalie Deboosere, Yves Rouillé, Lowiese Desmarets, Karin Séron, Adeline Danneels, Cyril Robil, Loic Belloy, Camille Moreau, Catherine Piveteau, Alexandre Biela, Alexandre Vandeputte, Séverine Heumel, Lucie Deruyter, Julie Dumont, Florence Leroux, Ilka Engelmann, Enagnon Kazali Alidjinou, Didier Hober, Priscille Brodin, Terence Beghyn, François Trottein, Benoit Deprez, Jean Dubuisson
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010498 (2022)
Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in one or several geographical areas, to identify those exhibiting antiviral activity against
Externí odkaz:
https://doaj.org/article/ef24a1fe221949deb66833f87060787b
Autor:
François Briand, Valentin Sencio, Cyril Robil, Séverine Heumel, Lucie Deruyter, Arnaud Machelart, Johanna Barthelemy, Gemma Bogard, Eik Hoffmann, Fabrice Infanti, Oliver Domenig, Audrey Chabrat, Virgile Richard, Vincent Prévot, Ruben Nogueiras, Isabelle Wolowczuk, Florence Pinet, Thierry Sulpice, François Trottein
Publikováno v:
Viruses, Vol 14, Iss 9, p 2067 (2022)
Obese patients with non-alcoholic steatohepatitis (NASH) are prone to severe forms of COVID-19. There is an urgent need for new treatments that lower the severity of COVID-19 in this vulnerable population. To better replicate the human context, we se
Externí odkaz:
https://doaj.org/article/e0f3dac631bc44eea379559d5efb400a
Autor:
Stéphanie Solier, Sebastian Müller, Tatiana Cañeque, Antoine Versini, Arnaud Mansart, Fabien Sindikubwabo, Leeroy Baron, Laila Emam, Pierre Gestraud, G. Dan Pantoș, Vincent Gandon, Christine Gaillet, Ting-Di Wu, Florent Dingli, Damarys Loew, Sylvain Baulande, Sylvère Durand, Valentin Sencio, Cyril Robil, François Trottein, David Péricat, Emmanuelle Näser, Céline Cougoule, Etienne Meunier, Anne-Laure Bègue, Hélène Salmon, Nicolas Manel, Alain Puisieux, Sarah Watson, Mark A. Dawson, Nicolas Servant, Guido Kroemer, Djillali Annane, Raphaël Rodriguez
Publikováno v:
Nature. 617:386-394
Inflammation is a complex physiological process triggered in response to harmful stimuli1. It involves cells of the immune system capable of clearing sources of injury and damaged tissues. Excessive inflammation can occur as a result of infection and