Effect of surface chemistry of polymeric nanoparticles on cutaneous penetration of cholecalciferol

Autor: Patrice Hildgen, Jimmy Faivre, Cyrielle Rakotovao, Jean-Michel Rabanel, Marie-Alexandrine Bolzinger, Xavier Banquy, Araceli Garcia Ac, Pierre-Luc Latreille, Stéphanie Briançon, Augustine Lalloz

Publikováno v: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2018, 553 (1-2), pp.120-131. ⟨10.1016/j.ijpharm.2018.09.046⟩

We investigated the influence of nanoparticle (NP) surface composition on different aspects of skin delivery of a lipophilic drug: chemical stability, release and skin penetration. Cholecalciferol was chosen as a labile model drug. Poly(lactic acid)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a02e1737ed2e3d6abbccd20bf56e9f
https://doi.org/10.1016/j.ijpharm.2018.09.046