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Alloantibodies against MHC Class I: A Novel Mechanism of Neonatal Pancytopenia Linked to Vaccination
Autor:
Caroline Lacroux, Cécile Caubet, Odile Burlet-Schiltz, C Tasca, Cyrielle Franchi, Catherine Trumel, François Schelcher, Gilles Foucras, Carole Pichereaux, Fabien Corbière
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2011, 187 (12), pp.6564-6570. ⟨10.4049/jimmunol.1102533⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2011, 187 (12), pp.6564-6570. ⟨10.4049/jimmunol.1102533⟩
Fetal/neonatal alloimmune thrombocytopenia is a frequent disease in humans where alloantibodies against platelet Ags lead to platelet destruction and hemorrhage. Although a role in the disease for Abs against MHC has been suspected, this has not been