Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Cyprian O Onyeji"'
Autor:
Xin Hui S Chan, Yan Naung Win, Ilsa L Haeusler, Jireh Y Tan, Shanghavie Loganathan, Sompob Saralamba, Shu Kiat S Chan, Elizabeth A Ashley, Karen I Barnes, Rita Baiden, Peter U Bassi, Abdoulaye Djimde, Grant Dorsey, Stephan Duparc, Borimas Hanboonkunupakarn, Feiko O Ter Kuile, Marcus V G Lacerda, Amit Nasa, François H Nosten, Cyprian O Onyeji, Sasithon Pukrittayakamee, André M Siqueira, Joel Tarning, Walter R J Taylor, Giovanni Valentini, Michèle van Vugt, David Wesche, Nicholas P J Day, Christopher L-H Huang, Josep Brugada, Ric N Price, Nicholas J White
Publikováno v:
PLoS Medicine, Vol 17, Iss 3, p e1003040 (2020)
BackgroundElectrocardiographic QT interval prolongation is the most widely used risk marker for ventricular arrhythmia potential and thus an important component of drug cardiotoxicity assessments. Several antimalarial medicines are associated with QT
Externí odkaz:
https://doaj.org/article/8ea6d1a043354012a21da11481816ea6
Autor:
Ayorinde Adehin, PhD, Sharon I. Igbinoba, PhD, Julius O. Soyinka, PhD, Cyprian O. Onyeji, PhD, Chinedum P. Babalola, PhD, Oluseye O. Bolaji, PhD
Publikováno v:
Current Therapeutic Research, Vol 91, Iss , Pp 33-38 (2019)
ABSTRACT: Background: The varied disposition of the antimalarial quinine partly explains its poor tolerance and toxicity in humans. Objective: Using a population approach, the disposition of quinine in healthy subjects and patients with acute uncompl
Externí odkaz:
https://doaj.org/article/1625d798358d4f67b942c59570f78b94
Autor:
Cyprian .O. ONYEJI
Publikováno v:
African Journal of Traditional, Complementary and Alternative Medicines. 18:27-35
Background: The therapeutic utility of herbal medicinal products including antimalarial herbal remedies has been hampered by some unfavorable biopharmaceutical properties of the bioactive constituents such as low aqueous solubility, poor oral bioavai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e4bf04f1e2f2c49feda91ba198f51a
https://doi.org/10.21010/ajtcamv18i1.3
https://doi.org/10.21010/ajtcamv18i1.3
Autor:
Ezekiel Omotoso, Julius O. Soyinkaa, Adebanjo J. Adegbola, Oluseye O. Bolaji, Olujide O. Olubiyi, Cyprian O. Onyeji
Publikováno v:
Journal of Pharmaceutical Research International. :92-105
Lumefantrine contributes significant roles in artemisinin-based combination therapy for malaria treatment but associated with a limitation of poor aqueous solubility and low permeability. This study investigated lumefantrine-2-hydroxypropyl-β-cyclod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e6b8694bd47e9fc9d5767d30e37ad58
https://doi.org/10.9734/jpri/2020/v32i1330589
https://doi.org/10.9734/jpri/2020/v32i1330589
Autor:
Cyprian O. Onyeji
Publikováno v:
African Journal of Traditional, Complementary and Alternative Medicines; Vol. 17 No. 1 (2020); 33-38
No Abstract.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd31ff76b2da44626db7af73b3402504
https://doi.org/10.21010/ajtcam.v17i1.4
https://doi.org/10.21010/ajtcam.v17i1.4
Publikováno v:
Journal of Pharmaceutical Research International. :15-24
Aim of the Study: Conventional antimalarial drugs are used concurrently with herbal remedies in malarial endemic developing countries. Vernonia amygdalina is one of such popular herbs used in the treatment of malaria. This study aimed at investigatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6fa9e21c5e52036bad948c0dd2b55b
https://doi.org/10.9734/jpri/2020/v32i330410
https://doi.org/10.9734/jpri/2020/v32i330410
Autor:
Oluseye O. Bolaji, Cyprian O. Onyeji, Sharon I. Igbinoba, Julius O. Soyinka, Ayorinde Adehin, Chinedum P. Babalola
Publikováno v:
Current Therapeutic Research, Vol 91, Iss, Pp 33-38 (2019)
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Clinical and Experimental
Highlights • Varied disposition imparts on the tolerance and safety of quinine, and thus constitutes a major limiting consideration for its dosing in uncomplicated malaria. Utilizing a population approach, the effect of body weight and infection st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ba045d0aaef60755fd922876ad642b
http://www.sciencedirect.com/science/article/pii/S0011393X19300165
http://www.sciencedirect.com/science/article/pii/S0011393X19300165
Autor:
Oluseye O. Bolaji, Julius O. Soyinka, Adebanjo J. Adegbola, Ibrahim Adebayo Hassan, Cyprian O. Onyeji
Publikováno v:
Am J Trop Med Hyg
Access to good-quality medicines remains a contentious issue in developing countries. This development is worrisome, particularly in a setting with a high incidence of malaria. Monitoring of antimalarial drugs in the commercial domain becomes necessa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838ccb56a2f2ad4585ce8d5d64f144da
https://pubmed.ncbi.nlm.nih.gov/32588802
https://pubmed.ncbi.nlm.nih.gov/32588802
Autor:
Michèle van Vugt, Marcus V. G. Lacerda, PU Bassi, Amit Nasa, Rita Baiden, Feiko O. ter Kuile, Karen I. Barnes, Xin Hui S Chan, Stephan Duparc, Giovanni Valentini, Nicholas P. J. Day, Cyprian O. Onyeji, Yan Naung Win, Sasithon Pukrittayakamee, Shu Kiat S. Chan, Elizabeth A. Ashley, Nicholas J. White, Christopher L.-H. Huang, François Nosten, Walter R. J. Taylor, Josep Brugada, Joel Tarning, André Siqueira, Ilsa L. Haeusler, Sompob Saralamba, Borimas Hanboonkunupakarn, David Wesche, Grant Dorsey, Jireh Y. Tan, Ric N. Price, Abdoulaye Djimde, Shanghavie Loganathan
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 17, Iss 3, p e1003040 (2020)
PLoS medicine, 17(3). Public Library of Science
PLoS Medicine, Vol 17, Iss 3, p e1003040 (2020)
PLoS medicine, 17(3). Public Library of Science
Background Electrocardiographic QT interval prolongation is the most widely used risk marker for ventricular arrhythmia potential and thus an important component of drug cardiotoxicity assessments. Several antimalarial medicines are associated with Q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769584c6e2b8c9d1327e1bdb58f4c8a3
https://www.repository.cam.ac.uk/handle/1810/303097
https://www.repository.cam.ac.uk/handle/1810/303097
Publikováno v:
Journal of Pharmaceutical Research International. 24:1-23
The oral route of administration is associated with some challenges such as poor aqueous solubility and low intestinal permeability of many active pharmaceutical ingredients resulting in decreased drug absorption and subsequent poor bioavailability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa4fddd68ab9d9fe5ced7f0100ee0d2
https://doi.org/10.9734/jpri/2018/45330
https://doi.org/10.9734/jpri/2018/45330